Protein: DUS10
Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5)

Gene: DUS10, DUSP10
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q9Y6W6

Gene Ontology (top 5):
GO:0002819 - regulation of adaptive immune response
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

853875

MK09
Mitogen-activated protein kinase 9

6

20

Small-scale

0.942

High

1158217

MK14
Mitogen-activated protein kinase 14

5

20

Small-scale

0.937

High

853763

MK08
Mitogen-activated protein kinase 8

5

20

Small-scale

0.932

High

168778

CSKP
Peripheral plasma membrane protein CASK

2

6

High-throughput

0.789

High

1198292

FND3B
Fibronectin type III domain-containing protein 3B

2

2

High-throughput

0.700

High

923404

MK10
Mitogen-activated protein kinase 10

1

20

Small-scale

0.665

High

953224

ACTB
Actin, cytoplasmic 1

2

18

High-throughput

0.628

High

977871

ACTA
Actin, aortic smooth muscle

2

17

High-throughput

0.628

High

1201103

ACTBL
Beta-actin-like protein 2

2

17

High-throughput

0.628

High

703759

MK01
Mitogen-activated protein kinase 1

1

20

High-throughput

0.618

High

1153385

MK11
Mitogen-activated protein kinase 11

1

20

Small-scale

0.618

High

1366690

SORL
Sortilin-related receptor

1

3

High-throughput

0.618

High

885460

HXA1
Homeobox protein Hox-A1

2

3

High-throughput

0.606

High

1419129

KRA32
Keratin-associated protein 3-2

2

0

High-throughput

0.580

High

1414534

EFHD1
EF-hand domain-containing protein D1

2

3

High-throughput

0.574

High

389591

FINC
Fibronectin

1

1

High-throughput

0.555

High

255512

SNX2
Sorting nexin-2

1

1

High-throughput

0.541

High

465705

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.541

High

844150

HD
Huntingtin

1

1

High-throughput

0.541

High

1034394

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.541

High

1101799

PTK7
Inactive tyrosine-protein kinase 7

1

12

High-throughput

0.541

High

1145801

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.541

High

995926

ACTC
Actin, alpha cardiac muscle 1

1

13

High-throughput

0.536

High

1032452

OTUD4
OTU domain-containing protein 4

1

1

High-throughput

0.536

High

973644

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.518

High

375062

RASH
GTPase HRas

1

11

High-throughput

0.515

High

384594

CRYAA
Alpha-crystallin A chain

1

6

High-throughput

0.515

High

442539

GELS
Gelsolin

1

3

High-throughput

0.515

High

1124104

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

High-throughput

0.515

High

1289908

Q86V38
Atrophin 1

1

2

High-throughput

0.515

High

1462111

UBQL1
Ubiquilin-1

1

3

High-throughput

0.515

High

1123189

FHL2
Four and a half LIM domains protein 2

1

2

High-throughput

0.481

High

155819

TXND9
Thioredoxin domain-containing protein 9

1

3

High-throughput

0.479

High

281272

CDC45
Cell division control protein 45 homolog

1

1

High-throughput

0.479

High

289199

PRDM1
PR domain zinc finger protein 1

1

2

Small-scale

0.479

High

299809

MPDZ
Multiple PDZ domain protein

1

5

High-throughput

0.479

High

303010

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

2

High-throughput

0.479

High

344050

HS74L
Heat shock 70 kDa protein 4L

1

9

High-throughput

0.479

High

607681

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

6

High-throughput

0.479

High

718077

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

5

High-throughput

0.479

High

764479

CTNA1
Catenin alpha-1

1

2

High-throughput

0.479

High

862739

UTRN
Utrophin

1

3

High-throughput

0.479

High

991138

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

4

High-throughput

0.479

High

994440

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

5

High-throughput

0.479

High

1006131

DLG4
Disks large homolog 4

1

6

High-throughput

0.479

High

1060944

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

2

High-throughput

0.479

High

1091606

DLG1
Disks large homolog 1

1

6

High-throughput

0.479

High

1105120

TCOF
Treacle protein

1

3

High-throughput

0.479

High

1116630

FHL3
Four and a half LIM domains protein 3

1

2

High-throughput

0.479

High

1149484

SKI2
Superkiller complex protein 2

1

5

High-throughput

0.479

High

1204824

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

3

High-throughput

0.479

High

1212222

MPP7
MAGUK p55 subfamily member 7

1

5

High-throughput

0.479

High

1226763

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

4

High-throughput

0.479

High

1244395

SKI3
Superkiller complex protein 3

1

7

High-throughput

0.479

High

1365931

NU205
Nuclear pore complex protein Nup205

1

4

High-throughput

0.479

High

1369808

RAD50
DNA repair protein RAD50

1

13

High-throughput

0.479

High

1428712

SKI8
Superkiller complex protein 8

1

2

High-throughput

0.479

High

1439592

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

7

High-throughput

0.479

High

1450024

LIN7C
Protein lin-7 homolog C

1

10

High-throughput

0.479

High

1460975

FBX3
F-box only protein 3

1

1

High-throughput

0.479

High

1462624

DICER
Endoribonuclease Dicer

1

8

High-throughput

0.479

High

1491316

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

2

High-throughput

0.479

High

650519

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.470

High

1133935

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

2

High-throughput

0.470

High

1410245

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.460

High

892966

MRE11
Double-strand break repair protein MRE11

1

0

High-throughput

0.458

High

964785

DCAF7
DDB1- and CUL4-associated factor 7

1

0

High-throughput

0.458

High

1081792

FP100
Fanconi anemia core complex-associated protein 100

1

0

High-throughput

0.458

High

1287506

PRUN1
Exopolyphosphatase PRUNE1

1

0

High-throughput

0.458

High

1458311

SPRR3
Small proline-rich protein 3

1

0

High-throughput

0.458

High

1380315

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

4

Small-scale

0.457

High

837373

ECI1
Enoyl-CoA delta isomerase 1, mitochondrial

1

2

High-throughput

0.437

High

1312098

DJC10
DnaJ homolog subfamily C member 10

1

4

High-throughput

0.437

High

1453416

HPBP1
Hsp70-binding protein 1

1

2

High-throughput

0.437

High

1491783

BACE2
Beta-secretase 2

1

0

High-throughput

0.268

Low

1451911

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.265

Low

772354

FBN2
Fibrillin-2 [Cleaved into: Placensin]

1

0

High-throughput

0.249

Low

1193593

CE022
UPF0489 protein C5orf22

1

0

High-throughput

0.249

Low

1461444

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025