Protein: TCAM1
TIR domain-containing adapter molecule 1 (TICAM-1) (Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta) (TIR domain-containing adapter protein inducing IFN-beta)

Gene: TCAM1, Ticam1
Organism: Mus musculus
Interactions: 23
UniProt ID: Q80UF7

Gene Ontology (top 5):
GO:0002281 - macrophage activation involved in immune response
GO:0002735 - positive regulation of myeloid dendritic cell cytokine production
GO:0002756 - MyD88-independent toll-like receptor signaling pathway
GO:0005739 - mitochondrion
GO:0005769 - early endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1282026

TLR4
Toll-like receptor 4

5

9

Small-scale

0.712

High

1221520

TRAF3
TNF receptor-associated factor 3

4

13

Small-scale

0.686

High

1282028

TBK1
Serine/threonine-protein kinase TBK1

4

4

Small-scale

0.683

High

1221635

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

13

Small-scale

0.618

High

1282027

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

4

Small-scale

0.618

High

999853

TRAF6
TNF receptor-associated factor 6

2

12

Small-scale

0.611

High

1282022

TLR3
Toll-like receptor 3

2

9

Small-scale

0.584

High

1189581

CBLB
E3 ubiquitin-protein ligase CBL-B

1

6

Small-scale

0.554

High

778173

BTK
Tyrosine-protein kinase BTK

1

11

Small-scale

0.536

High

869547

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.536

High

522172

BCL2
Apoptosis regulator Bcl-2

1

1

Small-scale

0.515

High

312662

BECN1
Beclin-1

1

0

Small-scale

0.493

High

1000256

TANK
TRAF family member-associated NF-kappa-B activator

1

1

Small-scale

0.479

High

1000530

IRF3
Interferon regulatory factor 3

1

5

Small-scale

0.479

High

1282020

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

2

Small-scale

0.479

High

1282021

DDX1
ATP-dependent RNA helicase DDX1

1

6

Small-scale

0.479

High

1282025

DDX21
Nucleolar RNA helicase 2

1

6

Small-scale

0.479

High

1282017

RNF41
E3 ubiquitin-protein ligase NRDP1

1

11

Small-scale

0.470

High

1282018

PAR12
Protein mono-ADP-ribosyltransferase PARP12

1

5

Small-scale

0.437

High

1282024

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

12

Small-scale

0.437

High

1190005

TRAD1
TRAF-type zinc finger domain-containing protein 1

1

0

Small-scale

0.249

Low

1282019

I17RD
Interleukin-17 receptor D

1

0

Small-scale

0.249

Low

1282023

Q9DAD3
WD repeat and FYVE domain containing 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025