Protein: IL12B
Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40)

Gene: IL12B
Organism: Mus musculus
Interactions: 15
UniProt ID: P43432

Gene Ontology (top 5):
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002230 - positive regulation of defense response to virus by host
GO:0002827 - positive regulation of T-helper 1 type immune response
GO:0002860 - positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002862 - negative regulation of inflammatory response to antigenic stimulus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849297

IL23A
Interleukin-23 subunit alpha

1

2

Small-scale

0.730

High

660930

IRF8
Interferon regulatory factor 8

4

8

Small-scale

0.687

High

849292

TF65
Transcription factor p65

4

6

Small-scale

0.676

High

583136

IRF1
Interferon regulatory factor 1

3

8

Small-scale

0.640

High

681968

NFKB1
Nuclear factor NF-kappa-B p105 subunit

3

4

Small-scale

0.640

High

849294

I12R1
Interleukin-12 receptor subunit beta-1

1

18

Small-scale

0.553

High

849289

IRF5
Interferon regulatory factor 5

1

8

Small-scale

0.479

High

849293

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

6

Small-scale

0.479

High

849295

IRF4
Interferon regulatory factor 4

1

8

Small-scale

0.479

High

849296

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

1

6

Small-scale

0.479

High

148218

NFIL3
Nuclear factor interleukin-3-regulated protein

1

5

Small-scale

0.437

High

482129

JUNB
Transcription factor JunB

1

6

Small-scale

0.437

High

849298

NCOR2
Nuclear receptor corepressor 2

1

1

Small-scale

0.437

High

849290

TF2B
Transcription initiation factor IIB

1

0

Small-scale

0.249

Low

849291

ETV6
Transcription factor ETV6

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025