Protein: DPYS
Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase)

Gene: DPYS
Organism: Homo sapiens
Interactions: 19
UniProt ID: Q14117

Gene Ontology (top 5):
GO:0004157 - dihydropyrimidinase activity
GO:0005829 - cytosol
GO:0006208 - pyrimidine nucleobase catabolic process
GO:0006210 - thymine catabolic process
GO:0006212 - uracil catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1120598

DPYL3
Dihydropyrimidinase-related protein 3

2

16

High-throughput

0.811

High

1120600

DPYL2
Dihydropyrimidinase-related protein 2

2

16

High-throughput

0.811

High

1120604

DPYL5
Dihydropyrimidinase-related protein 5

2

16

High-throughput

0.811

High

155849

DPYL4
Dihydropyrimidinase-related protein 4

1

17

High-throughput

0.691

High

1120602

APBP2
Amyloid protein-binding protein 2

2

1

High-throughput

0.553

High

167265

KLF11
Krueppel-like factor 11

1

3

High-throughput

0.515

High

442314

GELS
Gelsolin

1

1

High-throughput

0.515

High

856683

BAG6
Large proline-rich protein BAG6

1

3

High-throughput

0.515

High

1120607

UBQL1
Ubiquilin-1

1

3

High-throughput

0.515

High

374592

RASH
GTPase HRas

1

0

High-throughput

0.493

High

702437

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

1120603

ZDH15
Palmitoyltransferase ZDHHC15

1

1

Small-scale

0.479

High

650160

FGFR3
Fibroblast growth factor receptor 3

1

9

High-throughput

0.470

High

1120599

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

7

High-throughput

0.470

High

1120605

NUP58
Nucleoporin p58/p45

1

1

High-throughput

0.470

High

1120601

TM41B
Transmembrane protein 41B

1

1

High-throughput

0.437

High

1120606

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

159971

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.268

Low

770662

ADML
Pro-adrenomedullin [Cleaved into: Adrenomedullin

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025