Protein: DPYL5
Dihydropyrimidinase-related protein 5 (DRP-5) (CRMP3-associated molecule) (CRAM) (Collapsin response mediator protein 5) (CRMP-5) (UNC33-like phosphoprotein 6) (ULIP-6)

Gene: DPYL5, DPYSL5
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q9BPU6

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0007399 - nervous system development
GO:0007411 - axon guidance
GO:0016812 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1158698

DPYL2
Dihydropyrimidinase-related protein 2

7

18

High-throughput

0.971

High

1123272

DPYL3
Dihydropyrimidinase-related protein 3

4

16

High-throughput

0.902

High

155874

DPYL4
Dihydropyrimidinase-related protein 4

3

18

High-throughput

0.855

High

1120604

DPYS
Dihydropyrimidinase

2

16

High-throughput

0.811

High

1164233

DGUOK
Deoxyguanosine kinase, mitochondrial

3

4

High-throughput

0.667

High

1409534

KLDC3
Kelch domain-containing protein 3

3

5

High-throughput

0.667

High

1409536

KTU
Protein kintoun

3

5

High-throughput

0.667

High

1409538

NUFP1
FMR1-interacting protein NUFIP1

3

4

High-throughput

0.667

High

124464

HAX1
HCLS1-associated protein X-1

3

5

High-throughput

0.609

High

187398

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

2

0

High-throughput

0.602

High

760844

GLYC
Serine hydroxymethyltransferase, cytosolic

2

0

High-throughput

0.602

High

1168951

LONF2
LON peptidase N-terminal domain and RING finger protein 2

2

4

High-throughput

0.574

High

1279022

TAFA3
Chemokine-like protein TAFA-3

2

1

High-throughput

0.574

High

1307243

TF2LY
Homeobox protein TGIF2LY

2

1

High-throughput

0.574

High

537793

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.571

High

868763

LEG7
Galectin-7

2

3

High-throughput

0.558

High

691374

1433T
14-3-3 protein theta

1

7

High-throughput

0.536

High

906923

GPM6A
Neuronal membrane glycoprotein M6-a

1

4

High-throughput

0.536

High

966805

1433G
14-3-3 protein gamma

1

7

High-throughput

0.536

High

1049717

1433F
14-3-3 protein eta

1

7

High-throughput

0.536

High

1115957

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.536

High

1293406

CARM1
Histone-arginine methyltransferase CARM1

1

2

High-throughput

0.536

High

1310781

CUL9
Cullin-9

1

4

High-throughput

0.536

High

106551

APRIO
Alternative prion protein

2

4

High-throughput

0.533

High

1409539

DP13A
DCC-interacting protein 13-alpha

1

0

High-throughput

0.518

High

167376

KLF11
Krueppel-like factor 11

1

3

High-throughput

0.515

High

231755

PEX1
Peroxisomal ATPase PEX1

1

10

High-throughput

0.515

High

246117

KIF1B
Kinesin-like protein KIF1B

1

2

High-throughput

0.515

High

301658

WFS1
Wolframin

1

1

High-throughput

0.515

High

415820

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.515

High

442459

GELS
Gelsolin

1

1

High-throughput

0.515

High

843916

HD
Huntingtin

1

6

High-throughput

0.515

High

981668

RAN
GTP-binding nuclear protein Ran

1

1

High-throughput

0.515

High

1133916

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

7

High-throughput

0.515

High

1409540

UBQL1
Ubiquilin-1

1

3

High-throughput

0.515

High

1146398

LRC41
Leucine-rich repeat-containing protein 41

1

0

High-throughput

0.513

High

1244579

SYDM
Aspartate--tRNA ligase, mitochondrial

1

3

High-throughput

0.494

High

131009

HIP1
Huntingtin-interacting protein 1

1

0

High-throughput

0.493

High

937098

CASP6
Caspase-6

1

0

High-throughput

0.493

High

946087

ANTR2
Anthrax toxin receptor 2

1

1

High-throughput

0.489

High

1390095

MMAB
Corrinoid adenosyltransferase MMAB

1

2

High-throughput

0.489

High

242723

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

412512

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.479

High

457650

TBB5
Tubulin beta chain

1

7

High-throughput

0.479

High

462595

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.479

High

831315

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

905077

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.479

High

970974

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

995792

ACTC
Actin, alpha cardiac muscle 1

1

4

High-throughput

0.479

High

1140753

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1259456

TBA1A
Tubulin alpha-1A chain

1

13

High-throughput

0.479

High

1350428

BICD2
Protein bicaudal D homolog 2

1

5

High-throughput

0.479

High

1408469

VRK1
Serine/threonine-protein kinase VRK1

1

2

High-throughput

0.479

High

1409537

ARMC1
Armadillo repeat-containing protein 1

1

3

High-throughput

0.479

High

280798

PR40A
Pre-mRNA-processing factor 40 homolog A

1

8

High-throughput

0.470

High

650378

FGFR3
Fibroblast growth factor receptor 3

1

9

High-throughput

0.470

High

1341304

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.470

High

223287

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

849399

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.458

High

914332

EFNA4
Ephrin-A4

1

0

High-throughput

0.458

High

1132930

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

1338338

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

535458

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.457

High

404885

PRIO
Major prion protein

1

1

High-throughput

0.445

High

530288

TAU
Microtubule-associated protein tau

1

10

High-throughput

0.445

High

935059

TERA
Transitional endoplasmic reticulum ATPase

1

10

High-throughput

0.445

High

1288914

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

3

High-throughput

0.445

High

1398339

CEP63
Centrosomal protein of 63 kDa

1

3

High-throughput

0.445

High

331265

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.437

High

406558

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.437

High

589524

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

696333

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

769007

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1255252

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

1290255

MGDP1
Magnesium-dependent phosphatase 1

1

2

High-throughput

0.437

High

1409535

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

1169431

SAMTR
S-adenosylmethionine sensor upstream of mTORC1

1

0

High-throughput

0.426

High

1409541

S12A4
Solute carrier family 12 member 4

1

1

High-throughput

0.407

High

1243085

CF161
Cilia- and flagella-associated protein 161

3

0

High-throughput

0.340

High

1280273

AP2D
Transcription factor AP-2-delta

1

0

High-throughput

0.279

Low

562353

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

702670

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.268

Low

1409542

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low

1409543

Q9Y649
GW128

1

0

High-throughput

0.268

Low

1065019

FGL1
Fibrinogen-like protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025