Protein: LIGO2
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 (Leucine-rich repeat neuronal protein 3) (Leucine-rich repeat neuronal protein 6C)

Gene: LIGO2, LINGO2
Organism: Homo sapiens
Interactions: 18
UniProt ID: Q7L985

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0031012 - extracellular matrix
GO:0051965 - positive regulation of synapse assembly
GO:0097060 - synaptic membrane
GO:0098978 - glutamatergic synapse

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1273096

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

3

17

High-throughput

0.861

High

658900

PTPRD
Receptor-type tyrosine-protein phosphatase delta

2

5

High-throughput

0.811

High

480840

LEG1
Galectin-1

2

7

High-throughput

0.628

High

1273091

S11IP
Serine/threonine-protein kinase 11-interacting protein

2

18

High-throughput

0.574

High

1273095

TRI11
E3 ubiquitin-protein ligase TRIM11

2

1

High-throughput

0.574

High

1273097

CNPY3
Protein canopy homolog 3

2

9

High-throughput

0.574

High

1273098

LMA2L
VIP36-like protein

2

1

High-throughput

0.574

High

1273099

SMUF2
E3 ubiquitin-protein ligase SMURF2

2

4

High-throughput

0.574

High

1036576

SEMG2
Semenogelin-2

1

0

High-throughput

0.513

High

422424

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

1037234

H11
Histone H1.1

1

1

High-throughput

0.489

High

1273100

UQCC1
Ubiquinol-cytochrome c reductase complex assembly factor 1

1

1

High-throughput

0.489

High

1273094

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

High-throughput

0.457

High

156300

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

2

0

High-throughput

0.328

High

337112

NPT2B
Sodium-dependent phosphate transport protein 2B

2

0

High-throughput

0.328

High

1273090

NNRD
ATP-dependent

2

0

High-throughput

0.328

High

1273092

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.279

Low

1273093

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025