Protein: TMG1
Transmembrane gamma-carboxyglutamic acid protein 1 (Proline-rich gamma-carboxyglutamic acid protein 1) (Proline-rich Gla protein 1)

Gene: TMG1, PRRG1
Organism: Homo sapiens
Interactions: 13
UniProt ID: O14668

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0007596 - blood coagulation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

160926

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

14

High-throughput

0.619

High

160933

NED4L
E3 ubiquitin-protein ligase NEDD4-like

2

14

High-throughput

0.565

High

160924

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

2

1

High-throughput

0.553

High

160925

VKGC
Vitamin K-dependent gamma-carboxylase

1

2

High-throughput

0.536

High

160927

YAP1
Transcriptional coactivator YAP1

1

18

High-throughput

0.536

High

160932

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

14

High-throughput

0.536

High

160934

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

14

High-throughput

0.536

High

160929

STXB4
Syntaxin-binding protein 4

1

1

High-throughput

0.489

High

160930

HECW1
E3 ubiquitin-protein ligase HECW1

1

14

High-throughput

0.489

High

160935

HECW2
E3 ubiquitin-protein ligase HECW2

1

14

High-throughput

0.489

High

160928

DCA10
DDB1- and CUL4-associated factor 10

1

0

High-throughput

0.279

Low

160936

FBX10
F-box only protein 10

1

0

High-throughput

0.279

Low

160931

FBX25
F-box only protein 25

1

0

Small-scale

0.261

Low


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Last updated: 11Aug2025