HitPredict

Interactor 1: RAB7L (O14966)
Ras-related protein Rab-7L1 (Rab-7-like protein 1) (Ras-related protein Rab-29)
Gene: RAB29

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.883

The method score is based on:

Property Details
Experiments 24510904, 35266954, 31552791
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy, protein array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Ras, Ras~Roc
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005764 - lysosome
and 12 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024