Protein: DCA10
DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32)

Gene: DCA10, DCAF10
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q5QP82

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0016567 - protein ubiquitination
GO:0080008 - Cul4-RING E3 ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1208959

ARP8
Actin-related protein 8

3

11

High-throughput

0.861

High

1157752

DDB1
DNA damage-binding protein 1

3

20

Small-scale

0.847

High

899421

TCPD
T-complex protein 1 subunit delta

2

20

High-throughput

0.776

High

618463

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

3

8

High-throughput

0.770

High

881958

TCPG
T-complex protein 1 subunit gamma

3

20

High-throughput

0.742

High

610699

TCPA
T-complex protein 1 subunit alpha

2

20

High-throughput

0.694

High

1007058

TCPB
T-complex protein 1 subunit beta

2

20

High-throughput

0.694

High

1208951

TCPH
T-complex protein 1 subunit eta

2

20

High-throughput

0.694

High

1115242

CUL4B
Cullin-4B

4

20

Small-scale

0.694

High

1208943

FBXW5
F-box/WD repeat-containing protein 5

1

1

High-throughput

0.691

High

1208938

HDAC7
Histone deacetylase 7

3

18

High-throughput

0.667

High

1208969

ZMAT5
Zinc finger matrin-type protein 5

1

0

High-throughput

0.656

High

1114872

CUL4A
Cullin-4A

3

20

Small-scale

0.656

High

341073

DIRA3
GTP-binding protein Di-Ras3

4

5

High-throughput

0.630

High

1102843

EIF3I
Eukaryotic translation initiation factor 3 subunit I

4

16

High-throughput

0.630

High

1208973

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

4

4

High-throughput

0.630

High

291810

STK16
Serine/threonine-protein kinase 16

2

5

High-throughput

0.628

High

458425

ADRB2
Beta-2 adrenergic receptor

1

2

High-throughput

0.625

High

1208923

CORO6
Coronin-6

1

18

High-throughput

0.618

High

1208941

TCPW
T-complex protein 1 subunit zeta-2

1

20

High-throughput

0.618

High

1208972

DAPP1
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

1

5

High-throughput

0.618

High

194225

R113A
E3 ubiquitin-protein ligase RNF113A

1

2

High-throughput

0.618

High

992789

RACK1
Small ribosomal subunit protein RACK1

1

20

High-throughput

0.618

High

1208952

DDA1
DET1- and DDB1-associated protein 1

1

3

High-throughput

0.618

High

1208956

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

18

High-throughput

0.618

High

350889

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

3

3

High-throughput

0.609

High

1208965

KBRS2
NF-kappa-B inhibitor-interacting Ras-like protein 2

3

6

High-throughput

0.604

High

1208944

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

17

High-throughput

0.575

High

1205813

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

20

High-throughput

0.574

High

1208924

CSN6
COP9 signalosome complex subunit 6

2

2

High-throughput

0.571

High

1208942

LHX4
LIM/homeobox protein Lhx4

2

1

High-throughput

0.553

High

303138

RGS20
Regulator of G-protein signaling 20

1

5

High-throughput

0.553

High

605005

HXB6
Homeobox protein Hox-B6

2

3

High-throughput

0.549

High

258920

DNJA2
DnaJ homolog subfamily A member 2

2

11

High-throughput

0.537

High

885582

PRI2
DNA primase large subunit

1

1

High-throughput

0.536

High

1103049

PPIL2
RING-type E3 ubiquitin-protein ligase PPIL2

1

4

High-throughput

0.536

High

1208934

SLX4
Structure-specific endonuclease subunit SLX4

1

9

High-throughput

0.536

High

1208957

SLAP2
Src-like-adapter 2

1

4

High-throughput

0.536

High

1208968

CSN7A
COP9 signalosome complex subunit 7a

1

1

High-throughput

0.536

High

1208970

HSPB8
Heat shock protein beta-8

1

4

High-throughput

0.536

High

1208918

OTUD1
OTU domain-containing protein 1

1

3

Small-scale

0.528

High

241913

PRKN
E3 ubiquitin-protein ligase parkin

1

18

High-throughput

0.515

High

75567

B3KSW4
Regulator of G protein signaling 20

1

2

High-throughput

0.514

High

821394

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.514

High

875999

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.514

High

1208919

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.514

High

885534

PRI1
DNA primase small subunit

1

0

High-throughput

0.513

High

508100

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

10

High-throughput

0.501

High

1006454

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.501

High

239086

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.489

High

317520

TPPP
Tubulin polymerization-promoting protein

1

1

High-throughput

0.489

High

347081

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.489

High

569251

YJU2B
Probable splicing factor YJU2B

1

2

High-throughput

0.489

High

688702

NKG2D
NKG2-D type II integral membrane protein

1

3

High-throughput

0.489

High

1208920

SE1L3
Protein sel-1 homolog 3

1

5

High-throughput

0.489

High

1208922

FXL19
F-box/LRR-repeat protein 19

1

6

High-throughput

0.489

High

1208931

ZN695
Zinc finger protein 695

1

1

High-throughput

0.489

High

1208935

KLH34
Kelch-like protein 34

1

3

High-throughput

0.489

High

1208936

SLAI1
SLAIN motif-containing protein 1

1

1

High-throughput

0.489

High

1208946

LOXL4
Lysyl oxidase homolog 4

1

1

High-throughput

0.489

High

1208948

WFKN1
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1

1

3

High-throughput

0.489

High

1208950

SCN2A
Sodium channel protein type 2 subunit alpha

1

4

High-throughput

0.489

High

1208962

CABP2
Calcium-binding protein 2

1

1

High-throughput

0.489

High

1208967

AKA7G
A-kinase anchor protein 7 isoform gamma

1

2

High-throughput

0.489

High

1208975

JERKL
Jerky protein homolog-like

1

1

High-throughput

0.489

High

1208960

MYG1
MYG1 exonuclease

1

0

High-throughput

0.479

High

166530

BACH1
Transcription regulator protein BACH1

1

6

Small-scale

0.479

High

447094

NPM
Nucleophosmin

1

4

High-throughput

0.479

High

455793

H10
Histone H1.0

1

1

High-throughput

0.479

High

658221

RS3
Small ribosomal subunit protein uS3

1

7

High-throughput

0.479

High

664761

CCND1
G1/S-specific cyclin-D1

1

5

Small-scale

0.479

High

767061

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

1

High-throughput

0.479

High

830875

CCNF
Cyclin-F

1

7

High-throughput

0.479

High

972443

RS14
Small ribosomal subunit protein uS11

1

5

High-throughput

0.479

High

991040

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

4

High-throughput

0.479

High

1045372

TF65
Transcription factor p65

1

3

High-throughput

0.479

High

1121415

KEAP1
Kelch-like ECH-associated protein 1

1

2

High-throughput

0.479

High

1208958

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1030456

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

1208963

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.458

High

1208971

AGO1
Protein argonaute-1

1

0

High-throughput

0.458

High

1150105

TCEA2
Transcription elongation factor A protein 2

1

3

High-throughput

0.457

High

958653

CSN2
COP9 signalosome complex subunit 2

1

3

High-throughput

0.445

High

1094348

CSN1
COP9 signalosome complex subunit 1

1

3

High-throughput

0.445

High

144272

ACACB
Acetyl-CoA carboxylase 2

1

13

High-throughput

0.437

High

248716

PEPL
Periplakin

1

20

High-throughput

0.437

High

293808

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.437

High

350601

TXD12
Thioredoxin domain-containing protein 12

1

2

High-throughput

0.437

High

425915

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

20

High-throughput

0.437

High

480817

LEG1
Galectin-1

1

8

High-throughput

0.437

High

587687

DESP
Desmoplakin

1

20

High-throughput

0.437

High

637557

FLNA
Filamin-A

1

15

High-throughput

0.437

High

732331

PRDX2
Peroxiredoxin-2

1

6

High-throughput

0.437

High

1010635

DCD
Dermcidin

1

2

High-throughput

0.437

High

1036740

DSG1
Desmoglein-1

1

4

High-throughput

0.437

High

1094188

ACACA
Acetyl-CoA carboxylase 1

1

13

High-throughput

0.437

High

1161009

FSCN1
Fascin

1

4

High-throughput

0.437

High

1178180

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

1208933

MSRB3
Methionine-R-sulfoxide reductase B3

1

2

High-throughput

0.437

High

1208937

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

3

High-throughput

0.437

High

1208939

NUDC2
NudC domain-containing protein 2

1

20

High-throughput

0.437

High

1208961

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

20

High-throughput

0.437

High

1208974

LC7L2
Putative RNA-binding protein Luc7-like 2

1

1

High-throughput

0.437

High

155762

TXND9
Thioredoxin domain-containing protein 9

1

6

High-throughput

0.407

High

844793

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.407

High

1208921

ZNT6
Zinc transporter 6

1

1

High-throughput

0.407

High

1208953

SFXN3
Sideroflexin-3

1

1

High-throughput

0.407

High

1208976

SNX11
Sorting nexin-11

4

0

High-throughput

0.360

High

1208926

NECA2
N-terminal EF-hand calcium-binding protein 2

2

0

High-throughput

0.328

High

1208929

CIR1
Corepressor interacting with RBPJ 1

2

0

High-throughput

0.328

High

165806

TR13B
Tumor necrosis factor receptor superfamily member 13B

2

0

High-throughput

0.313

High

282521

PAGE1
P antigen family member 1

2

0

High-throughput

0.313

High

1106783

VPP3
V-type proton ATPase 116 kDa subunit a 3

2

0

High-throughput

0.313

High

67046

ZN726
Zinc finger protein 726

1

0

High-throughput

0.279

Low

160928

TMG1
Transmembrane gamma-carboxyglutamic acid protein 1

1

0

High-throughput

0.279

Low

252216

ISK4
Serine protease inhibitor Kazal-type 4

1

0

High-throughput

0.279

Low

1208949

SORC2
VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain]

1

0

High-throughput

0.279

Low

1208954

RTF2
Replication termination factor 2

1

0

High-throughput

0.279

Low

1208955

SRXN1
Sulfiredoxin-1

1

0

High-throughput

0.279

Low

1208964

TM160
Transmembrane protein 160

1

0

High-throughput

0.279

Low

590989

LOX15
Polyunsaturated fatty acid lipoxygenase ALOX15

1

0

High-throughput

0.279

Low

1208927

PLPL5
Patatin-like phospholipase domain-containing protein 5

1

0

High-throughput

0.279

Low

1208930

SPA2L
Spermatogenesis-associated protein 2-like protein

1

0

High-throughput

0.279

Low

1208932

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

1208940

SPRY4
SPRY domain-containing protein 4

1

0

High-throughput

0.279

Low

1208947

SPTCS
Spatacsin

1

0

High-throughput

0.279

Low

158641

PRY
PTPN13-like protein, Y-linked

1

0

High-throughput

0.269

Low

716435

PRDX5
Peroxiredoxin-5, mitochondrial

1

0

High-throughput

0.269

Low

445000

S10A9
Protein S100-A9

1

0

High-throughput

0.249

Low

1142484

PLCL1
Inactive phospholipase C-like protein 1

1

0

High-throughput

0.249

Low

1208928

LBN
Limbin

1

0

High-throughput

0.249

Low

1208945

SCRN2
Secernin-2

1

0

High-throughput

0.249

Low

213159

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

Small-scale

0.238

Low

1208925

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

0

High-throughput

0.232

Low

1208966

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025