Protein: YAF2
YY1-associated factor 2

Gene: YAF2
Organism: Homo sapiens
Interactions: 198
UniProt ID: Q8IY57

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003712 - transcription coregulator activity
GO:0003713 - transcription coactivator activity
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

987989

RING1
E3 ubiquitin-protein ligase RING1

10

20

High-throughput

0.980

High

1222214

RING2
E3 ubiquitin-protein ligase RING2

11

20

Small-scale

0.979

High

718000

BMI1
Polycomb complex protein BMI-1

8

20

Small-scale

0.968

High

1197569

PCGF5
Polycomb group RING finger protein 5

7

20

High-throughput

0.963

High

1222217

PCGF1
Polycomb group RING finger protein 1

6

20

Small-scale

0.950

High

718409

PCGF2
Polycomb group RING finger protein 2

6

20

Small-scale

0.945

High

1108516

PCGF3
Polycomb group RING finger protein 3

5

20

High-throughput

0.927

High

1222219

PCGF6
Polycomb group RING finger protein 6

5

20

High-throughput

0.927

High

1222191

RYBP
RING1 and YY1-binding protein

3

3

High-throughput

0.861

High

475095

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

4

High-throughput

0.811

High

586844

CSK22
Casein kinase II subunit alpha'

10

4

High-throughput

0.757

High

934292

CSK21
Casein kinase II subunit alpha

8

4

High-throughput

0.752

High

1167267

BCOR
BCL-6 corepressor

8

8

Small-scale

0.752

High

1218678

MGAP
MAX gene-associated protein

6

3

High-throughput

0.733

High

1222195

KDM2B
Lysine-specific demethylase 2B

6

4

High-throughput

0.733

High

265679

E2F6
Transcription factor E2F6

5

7

High-throughput

0.718

High

931722

CSK2B
Casein kinase II subunit beta

5

1

High-throughput

0.718

High

1125887

BCORL
BCL-6 corepressor-like protein 1

5

8

High-throughput

0.718

High

1222207

LMBL2
Lethal(3)malignant brain tumor-like protein 2

5

4

High-throughput

0.718

High

903357

WDR5
WD repeat-containing protein 5

5

2

High-throughput

0.714

High

1222200

AUTS2
Autism susceptibility gene 2 protein

4

7

Small-scale

0.704

High

1050519

TFDP1
Transcription factor Dp-1

4

2

High-throughput

0.699

High

1222206

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

4

1

High-throughput

0.694

High

1027112

CBX3
Chromobox protein homolog 3

4

12

Small-scale

0.686

High

1079542

NEDD8
NEDD8

1

2

Small-scale

0.681

High

902959

DCAF7
DDB1- and CUL4-associated factor 7

3

7

High-throughput

0.675

High

898154

MAX
Protein max

3

4

Small-scale

0.667

High

1123630

DCAF6
DDB1- and CUL4-associated factor 6

3

3

High-throughput

0.667

High

928982

SKP1
S-phase kinase-associated protein 1

3

2

High-throughput

0.656

High

1222223

FBRS
Probable fibrosin-1

5

6

High-throughput

0.656

High

476031

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

Small-scale

0.647

High

1222189

YAF2
YY1-associated factor 2

1

3

Small-scale

0.647

High

358532

CO1A1
Collagen alpha-1(I) chain

2

1

High-throughput

0.628

High

962856

MDM2
E3 ubiquitin-protein ligase Mdm2

2

1

High-throughput

0.628

High

974495

ENL
Protein ENL

2

2

High-throughput

0.628

High

1019331

TRI26
Tripartite motif-containing protein 26

2

2

High-throughput

0.628

High

1117671

ARI4B
AT-rich interactive domain-containing protein 4B

2

1

High-throughput

0.628

High

1167106

MCAF1
Activating transcription factor 7-interacting protein 1

2

2

High-throughput

0.628

High

1222199

MORC4
MORC family CW-type zinc finger protein 4

2

1

High-throughput

0.628

High

1222226

CHD8
Chromodomain-helicase-DNA-binding protein 8

2

3

High-throughput

0.628

High

1222204

RIT1
GTP-binding protein Rit1

1

10

High-throughput

0.618

High

872286

RD23B
UV excision repair protein RAD23 homolog B

1

2

High-throughput

0.618

High

1072383

ELOB
Elongin-B

1

1

High-throughput

0.618

High

1222227

FBSL
Fibrosin-1-like protein

3

6

High-throughput

0.616

High

1222203

HDAC2
Histone deacetylase 2

2

2

High-throughput

0.611

High

903825

NTF2
Nuclear transport factor 2

2

2

High-throughput

0.606

High

1222202

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

2

3

High-throughput

0.606

High

1222211

EAF1
ELL-associated factor 1

2

1

High-throughput

0.606

High

1222218

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

2

2

High-throughput

0.606

High

1222238

MARE3
Microtubule-associated protein RP/EB family member 3

2

1

High-throughput

0.606

High

979325

UBXN1
UBX domain-containing protein 1

2

0

High-throughput

0.602

High

1086910

UBE2S
Ubiquitin-conjugating enzyme E2 S

2

0

High-throughput

0.602

High

1222192

PAF1
RNA polymerase II-associated factor 1 homolog

2

0

High-throughput

0.602

High

1222208

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

2

0

High-throughput

0.602

High

1222242

FBX7
F-box only protein 7

2

0

High-throughput

0.602

High

923103

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.586

High

347280

MYC
Myc proto-oncogene protein

2

7

Small-scale

0.585

High

246086

PP1RB
E3 ubiquitin-protein ligase PPP1R11

2

0

High-throughput

0.580

High

814988

LEG7
Galectin-7

2

0

High-throughput

0.580

High

1157566

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.580

High

1222222

IN80B
INO80 complex subunit B

2

0

High-throughput

0.580

High

1222230

IFT57
Intraflagellar transport protein 57 homolog

2

0

High-throughput

0.580

High

1222234

TLK1
Serine/threonine-protein kinase tousled-like 1

2

0

High-throughput

0.580

High

921899

RL30
Large ribosomal subunit protein eL30

2

0

High-throughput

0.559

High

158331

PCD17
Protocadherin-17

2

1

High-throughput

0.553

High

1129302

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

2

1

High-throughput

0.553

High

1129328

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

2

1

High-throughput

0.553

High

1222232

MARK1
Serine/threonine-protein kinase MARK1

2

2

High-throughput

0.553

High

632808

TYY1
Transcriptional repressor protein YY1

1

4

Small-scale

0.552

High

1222244

SETBP
SET-binding protein

1

0

High-throughput

0.549

High

890735

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

High-throughput

0.541

High

436038

CO1A2
Collagen alpha-2(I) chain

1

1

High-throughput

0.536

High

912984

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.536

High

949839

CBX1
Chromobox protein homolog 1

1

12

High-throughput

0.536

High

1038517

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.536

High

1071931

PCBP1
Poly(rC)-binding protein 1

1

3

High-throughput

0.536

High

1160939

CTR9
RNA polymerase-associated protein CTR9 homolog

1

1

High-throughput

0.536

High

1201983

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

High-throughput

0.536

High

1222228

XAGE1
X antigen family member 1

1

1

High-throughput

0.523

High

1191448

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

2

High-throughput

0.515

High

147175

FCHO1
F-BAR domain only protein 1

1

0

High-throughput

0.513

High

617216

LORI
Loricrin

1

0

High-throughput

0.513

High

1173076

FBX50
F-box only protein 50

1

0

High-throughput

0.513

High

1222209

ZN689
Zinc finger protein 689

1

0

High-throughput

0.513

High

1222216

DHB14
17-beta-hydroxysteroid dehydrogenase 14

1

0

High-throughput

0.513

High

1190488

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

1

High-throughput

0.489

High

987829

GABP1
GA-binding protein subunit beta-1

1

5

Small-scale

0.481

High

1222212

ZFP42
Zinc finger protein 42 homolog

1

4

Small-scale

0.481

High

123282

CBX4
E3 SUMO-protein ligase CBX4

1

12

High-throughput

0.479

High

171050

TBXT
T-box transcription factor T

1

3

High-throughput

0.479

High

237093

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

1

High-throughput

0.479

High

316090

CBX6
Chromobox protein homolog 6

1

12

High-throughput

0.479

High

432042

HS90A
Heat shock protein HSP 90-alpha

1

1

High-throughput

0.479

High

438339

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.479

High

445465

RSSA
Small ribosomal subunit protein uS2

1

1

High-throughput

0.479

High

449767

HMGB1
High mobility group protein B1

1

2

High-throughput

0.479

High

499911

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

502308

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.479

High

523872

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

524980

XRCC5
X-ray repair cross-complementing protein 5

1

1

High-throughput

0.479

High

555537

H2AX
Histone H2AX

1

2

High-throughput

0.479

High

596784

CD11B
Cyclin-dependent kinase 11B

1

1

High-throughput

0.479

High

620173

PAX7
Paired box protein Pax-7

1

3

High-throughput

0.479

High

620383

GATA2
Endothelial transcription factor GATA-2

1

3

High-throughput

0.479

High

620528

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

3

High-throughput

0.479

High

640537

DDX6
Probable ATP-dependent RNA helicase DDX6

1

5

High-throughput

0.479

High

641475

PAX6
Paired box protein Pax-6

1

3

High-throughput

0.479

High

641850

U2AF2
Splicing factor U2AF 65 kDa subunit

1

2

High-throughput

0.479

High

647095

1433T
14-3-3 protein theta

1

6

High-throughput

0.479

High

678647

METK2
S-adenosylmethionine synthase isoform type-2

1

1

High-throughput

0.479

High

683530

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.479

High

685724

PRDX2
Peroxiredoxin-2

1

2

High-throughput

0.479

High

730308

PRS7
26S proteasome regulatory subunit 7

1

3

High-throughput

0.479

High

850945

HDGF
Hepatoma-derived growth factor

1

2

High-throughput

0.479

High

858649

PPP5
Serine/threonine-protein phosphatase 5

1

1

High-throughput

0.479

High

884202

KLF3
Krueppel-like factor 3

1

4

High-throughput

0.479

High

893084

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

904032

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

3

High-throughput

0.479

High

909793

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.479

High

917566

H4
Histone H4

1

1

High-throughput

0.479

High

927284

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.479

High

943074

PHC1
Polyhomeotic-like protein 1

1

9

High-throughput

0.479

High

964024

SRSF2
Serine/arginine-rich splicing factor 2

1

2

High-throughput

0.479

High

967270

EWS
RNA-binding protein EWS

1

3

High-throughput

0.479

High

982255

1433F
14-3-3 protein eta

1

6

High-throughput

0.479

High

983435

MAD1
Max dimerization protein 1

1

4

Small-scale

0.479

High

985236

HME1
Homeobox protein engrailed-1

1

1

High-throughput

0.479

High

997801

RBBP4
Histone-binding protein RBBP4

1

5

High-throughput

0.479

High

1021319

FOXL1
Forkhead box protein L1

1

1

High-throughput

0.479

High

1043095

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

1059172

CBX2
Chromobox protein homolog 2

1

12

High-throughput

0.479

High

1220849

PHC2
Polyhomeotic-like protein 2

1

7

High-throughput

0.479

High

1222193

PHC3
Polyhomeotic-like protein 3

1

8

High-throughput

0.479

High

1222194

CSK23
Casein kinase II subunit alpha 3

1

4

High-throughput

0.479

High

1222197

SP7
Transcription factor Sp7

1

3

High-throughput

0.479

High

1222201

DDX1
ATP-dependent RNA helicase DDX1

1

6

High-throughput

0.479

High

1222205

TNPO1
Transportin-1

1

2

High-throughput

0.479

High

1222210

SCMH1
Polycomb protein SCMH1

1

11

High-throughput

0.479

High

1222213

SRPK1
SRSF protein kinase 1

1

5

High-throughput

0.479

High

1222221

FOXQ1
Forkhead box protein Q1

1

2

High-throughput

0.479

High

1222225

CBX8
Chromobox protein homolog 8

1

12

High-throughput

0.479

High

1222233

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1222236

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

1222239

CD11A
Cyclin-dependent kinase 11A

1

1

High-throughput

0.479

High

103789

G5E9A7
DM1 locus, WD repeat containing

1

4

High-throughput

0.470

High

660609

GRN
Progranulin

1

1

High-throughput

0.470

High

124626

CLIC1
Chloride intracellular channel protein 1

1

0

High-throughput

0.458

High

153465

PDCD5
Programmed cell death protein 5

1

0

Small-scale

0.458

High

199052

PAPS1
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

1

0

High-throughput

0.458

High

210919

GET3
ATPase GET3

1

0

High-throughput

0.458

High

214987

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

216535

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

0

High-throughput

0.458

High

340489

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.458

High

382065

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

400986

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

414645

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.458

High

444200

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.458

High

453468

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

504372

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

531208

EF2
Elongation factor 2

1

0

High-throughput

0.458

High

546005

MYOD1
Myoblast determination protein 1

1

0

High-throughput

0.458

High

559815

H12
Histone H1.2

1

0

High-throughput

0.458

High

674954

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.458

High

713556

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

759728

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

786386

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

High-throughput

0.458

High

806077

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

843550

PAPOA
Poly(A) polymerase alpha

1

0

High-throughput

0.458

High

898386

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.458

High

905679

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

906528

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

0

High-throughput

0.458

High

931267

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

932776

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.458

High

1078582

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.458

High

1186244

PHF5A
PHD finger-like domain-containing protein 5A

1

0

High-throughput

0.458

High

1222196

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1222215

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.458

High

1222220

API5
Apoptosis inhibitor 5

1

0

High-throughput

0.458

High

1222224

CLK4
Dual specificity protein kinase CLK4

1

0

High-throughput

0.458

High

1222231

CDK12
Cyclin-dependent kinase 12

1

0

High-throughput

0.458

High

1222240

NUDC
Nuclear migration protein nudC

1

0

High-throughput

0.458

High

1222241

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.458

High

1222243

CFA20
Cilia- and flagella-associated protein 20

1

0

High-throughput

0.458

High

1222237

TRI33
E3 ubiquitin-protein ligase TRIM33

1

2

Small-scale

0.445

High

72311

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

5

High-throughput

0.437

High

66409

A2ML1
Alpha-2-macroglobulin-like protein 1

1

5

High-throughput

0.407

High

1222190

AGGF1
Angiogenic factor with G patch and FHA domains 1

2

0

High-throughput

0.328

High

1222198

CLM1
CMRF35-like molecule 1

2

0

High-throughput

0.316

High

1222229

DAAF6
Dynein axonemal assembly factor 6

2

0

High-throughput

0.316

High

1079039

CYTM
Cystatin-M

1

0

High-throughput

0.279

Low

1083757

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

1161177

CXB7
Gap junction beta-7 protein

1

0

High-throughput

0.279

Low

1165457

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

1222235

MYH13
Myosin-13

1

0

High-throughput

0.279

Low

246005

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.249

Low

329827

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

847300

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024