Protein: HERC6
Probable E3 ubiquitin-protein ligase HERC6 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 6) (HECT-type E3 ubiquitin transferase HERC6)

Gene: HERC6
Organism: Homo sapiens
Interactions: 18
UniProt ID: Q8IVU3

Gene Ontology (top 5):
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

168549

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

2

20

High-throughput

0.789

High

995988

UB2L3
Ubiquitin-conjugating enzyme E2 L3

2

20

Small-scale

0.778

High

1138972

HERC3
Probable E3 ubiquitin-protein ligase HERC3

1

17

Small-scale

0.665

High

1309275

HERC6
Probable E3 ubiquitin-protein ligase HERC6

1

17

Small-scale

0.647

High

1204533

HERC4
Probable E3 ubiquitin-protein ligase HERC4

1

16

Small-scale

0.618

High

1309276

ASB11
Ankyrin repeat and SOCS box protein 11

1

5

High-throughput

0.618

High

1309279

UBQL2
Ubiquilin-2

1

16

Small-scale

0.618

High

1309278

LATS2
Serine/threonine-protein kinase LATS2

1

20

High-throughput

0.536

High

648192

NDKB
Nucleoside diphosphate kinase B

1

3

Small-scale

0.481

High

404194

GCR
Glucocorticoid receptor

1

17

High-throughput

0.479

High

414156

P53
Cellular tumor antigen p53

1

17

High-throughput

0.479

High

461678

HS90A
Heat shock protein HSP 90-alpha

1

15

High-throughput

0.479

High

468571

HS90B
Heat shock protein HSP 90-beta

1

15

High-throughput

0.479

High

775183

FUS
RNA-binding protein FUS

1

13

High-throughput

0.479

High

958986

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

4

High-throughput

0.479

High

1227010

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.445

High

1309277

KCD15
BTB/POZ domain-containing protein KCTD15

1

4

Small-scale

0.437

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025