Protein: HCD2
3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-hydroxysteroid dehydrogenase 10) (17-beta-HSD 10) (EC 1.1.1.51, EC 1.1.1.62) (3-hydroxyacyl-CoA dehydrogenase type II) (Hydroxysteroid dehydrogenase) (EC 1.1.1.-, EC 1.1.1.53) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Scully protein) (Type II HADH)

Gene: HCD2, scu
Organism: Drosophila melanogaster
Interactions: 85
UniProt ID: O18404

Gene Ontology (top 5):
GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity
GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006631 - fatty acid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

185971

MRRP1
Mitochondrial ribonuclease P protein 1 homolog

2

1

Small-scale

0.775

High

185965

Q0E8E8
MIP08013p1

1

2

High-throughput

0.508

High

116298

M9PI17
Aldo-keto reductase 1B, isoform D

1

1

High-throughput

0.479

High

185953

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.479

High

185955

ENO
Enolase

1

2

High-throughput

0.479

High

185961

MOEH
Moesin/ezrin/radixin homolog 1

1

1

High-throughput

0.479

High

185962

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

2

High-throughput

0.479

High

185967

DIAP2
Death-associated inhibitor of apoptosis 2

1

3

High-throughput

0.479

High

185973

Q7JX87
Peroxiredoxin 2540-2

1

6

High-throughput

0.479

High

185975

Q7K148
Proteasome subunit beta

1

1

High-throughput

0.479

High

185983

Q8MT58
Carnosine dipeptidase 2, isoform A

1

1

High-throughput

0.479

High

185986

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

2

High-throughput

0.479

High

185987

Q95RF6
LD34461p

1

1

High-throughput

0.479

High

185994

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

2

High-throughput

0.479

High

185997

THIO2
Thioredoxin-2

1

1

High-throughput

0.479

High

185999

Q9VEB1
Malate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

186003

Q9VHN7
transketolase

1

1

High-throughput

0.479

High

186005

Q9VKW5
Prolyl endopeptidase

1

1

High-throughput

0.479

High

186006

Q9VL70
HL08109p

1

2

High-throughput

0.479

High

186013

Q9VTY2
Uncharacterized protein, isoform A

1

1

High-throughput

0.479

High

186015

Q9VU35
RH34413p

1

1

High-throughput

0.479

High

186016

Q9VW59
LD16419p

1

1

High-throughput

0.479

High

186018

PGPLE
Peptidoglycan-recognition protein LE

1

2

High-throughput

0.479

High

186020

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.479

High

186021

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

1

Small-scale

0.479

High

185949

O61604
Fimbrin

1

0

High-throughput

0.458

High

185964

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

185977

IMD
Protein immune deficiency

1

0

High-throughput

0.458

High

185980

Q8IRD3
Glutathione peroxidase

1

0

High-throughput

0.458

High

185981

Q8IRS7
Ciboulot, isoform C

1

0

High-throughput

0.458

High

185982

CASP8
Caspase-8

1

0

High-throughput

0.458

High

185991

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.458

High

185993

FADD
Fas-associated death domain protein

1

0

High-throughput

0.458

High

185998

Q9VAN7
Phosphoglycerate mutase

1

0

High-throughput

0.458

High

186000

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

0

High-throughput

0.458

High

186002

Q9VGM2
Fatty acid binding protein, isoform B

1

0

High-throughput

0.458

High

186004

ZUC
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.458

High

185951

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

1

High-throughput

0.445

High

185966

Q0KHS0
Katanin p80 WD40 repeat-containing subunit B1

1

4

High-throughput

0.445

High

48149

A0AVV3
Dorsal root ganglia homeobox, isoform E

1

2

High-throughput

0.439

High

51590

A1Z6P8
Exchange protein directly activated by cAMP, isoform E

1

1

High-throughput

0.439

High

186023

X2JCD3
Uncharacterized protein, isoform D

1

2

High-throughput

0.439

High

55745

A1ZB71
Glutathione S transferase E6

1

1

High-throughput

0.437

High

115035

M9PE30
Transgelin

1

2

High-throughput

0.437

High

185665

O18335
Rab11

1

1

High-throughput

0.437

High

185950

O97102
Small ubiquitin-related modifier

1

1

High-throughput

0.437

High

185956

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.437

High

185957

ANX10
Annexin B10

1

1

High-throughput

0.437

High

185960

UCHL
Ubiquitin carboxyl-terminal hydrolase

1

1

High-throughput

0.437

High

185963

PDI
Protein disulfide-isomerase

1

1

High-throughput

0.437

High

185974

Q7K0B6
Glutathione S transferase T1

1

1

High-throughput

0.437

High

185984

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

1

1

High-throughput

0.437

High

185985

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.437

High

185989

PGPLC
Peptidoglycan-recognition protein LC

1

2

High-throughput

0.437

High

185995

Q9V3V2
peptidylprolyl isomerase

1

2

High-throughput

0.437

High

186001

Q9VGK3
peptidylprolyl isomerase

1

2

High-throughput

0.437

High

186007

Q9VPN5
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.437

High

186011

Q9VRD6
NTF2-related export protein

1

1

High-throughput

0.437

High

186012

Q9VSL2
Glutathione S transferase O3

1

1

High-throughput

0.437

High

185976

Q7K3Z6
Exchange protein directly activated by cAMP, isoform D

1

1

High-throughput

0.417

High

186014

Q9VU13
LD45603p

1

2

High-throughput

0.417

High

185970

Q6QU65
ADAM metalloprotease

1

1

High-throughput

0.407

High

55053

A1ZAC8
Uncharacterized protein, isoform B

1

0

High-throughput

0.265

Low

185972

Q7JWN2
RE25177p

1

0

High-throughput

0.265

Low

186009

Q9VQ94
LP05220p

1

0

High-throughput

0.265

Low

186017

Q9VXA7
C2H2-type domain-containing protein

1

0

High-throughput

0.265

Low

53792

A1Z921
Frazzled, isoform B

1

0

Small-scale

0.249

Low

55794

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.249

Low

183513

O16043
Anon1A4

1

0

High-throughput

0.249

Low

185952

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.249

Low

185954

NDKA
Nucleoside diphosphate kinase

1

0

High-throughput

0.249

Low

185958

PROF
Profilin

1

0

High-throughput

0.249

Low

185959

CALR
Calreticulin

1

0

High-throughput

0.249

Low

185968

NLP
Nucleoplasmin-like protein

1

0

High-throughput

0.249

Low

185969

Q6NQZ7
LD40663p

1

0

High-throughput

0.249

Low

185978

Q86BM5
A kinase anchor protein 200, isoform D

1

0

High-throughput

0.249

Low

185988

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.249

Low

185990

IF5A
Eukaryotic translation initiation factor 5A

1

0

High-throughput

0.249

Low

185992

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

0

High-throughput

0.249

Low

185996

Q9V3V9
Endonuclease G inhibitor, isoform A

1

0

High-throughput

0.249

Low

186008

Q9VPX6
Adenylyl cyclase-associated protein

1

0

High-throughput

0.249

Low

186010

BACC
Bacchus

1

0

High-throughput

0.249

Low

186019

Q9VYR1
Regucalcin homologue

1

0

High-throughput

0.249

Low

186022

Q9XZ57
Eb1, isoform E

1

0

High-throughput

0.249

Low

185979

Q8IPU8
BNIP3, isoform B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024