Protein: PARG
Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143)

Gene: PARG
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q86W56

Gene Ontology (top 5):
GO:0004649 - poly(ADP-ribose) glycohydrolase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

487489

PARP1
Poly [ADP-ribose] polymerase 1

2

5

Small-scale

0.571

High

185824

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

Small-scale

0.537

High

1292090

SPSB4
SPRY domain-containing SOCS box protein 4

1

1

High-throughput

0.536

High

617318

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

0

High-throughput

0.513

High

799262

BRCA1
Breast cancer type 1 susceptibility protein

1

2

Small-scale

0.501

High

840075

CASP3
Caspase-3

1

0

Small-scale

0.480

High

551139

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.458

High

582860

EZRI
Ezrin

1

0

High-throughput

0.458

High

589073

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

687450

PTBP1
Polypyrimidine tract-binding protein 1

1

0

High-throughput

0.458

High

768571

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

831006

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

853327

CBX5
Chromobox protein homolog 5

1

0

High-throughput

0.458

High

980893

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1067479

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1100080

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1113585

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1136097

PAF15
PCNA-associated factor

1

0

Small-scale

0.458

High

1254475

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1289432

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1292089

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

1292091

BARD1
BRCA1-associated RING domain protein 1

1

0

Small-scale

0.458

High

1292092

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1292094

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1292097

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1292098

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1292095

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

1292096

CENPM
Centromere protein M

1

0

High-throughput

0.426

High

412198

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1292093

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025