Protein: RGS5
Regulator of G-protein signaling 5 (RGS5)

Gene: RGS5
Organism: Homo sapiens
Interactions: 16
UniProt ID: O15539

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

193876

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

2

20

Small-scale

0.768

High

193879

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

2

20

Small-scale

0.768

High

193880

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

2

20

Small-scale

0.768

High

193883

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

20

Small-scale

0.618

High

193887

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

20

Small-scale

0.618

High

193882

OMP
Olfactory marker protein

1

0

High-throughput

0.513

High

193877

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

193878

ADRB2
Beta-2 adrenergic receptor

1

8

Small-scale

0.481

High

193885

RAB5C
Ras-related protein Rab-5C

1

1

High-throughput

0.479

High

193888

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

193886

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.458

High

193890

AEDO
2-aminoethanethiol dioxygenase

1

1

Small-scale

0.445

High

193884

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

193875

CST8
Cystatin-8

1

0

High-throughput

0.279

Low

193889

RP25L
Ribonuclease P protein subunit p25-like protein

1

0

High-throughput

0.279

Low

193881

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025