Protein: RP25L
Ribonuclease P protein subunit p25-like protein (RNase P protein subunit-like p25) (Rpp25-like protein)

Gene: RP25L, RPP25L
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q8N5L8

Gene Ontology (top 5):
GO:0000172 - ribonuclease MRP complex
GO:0001682 - tRNA 5'-leader removal
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

294939

POP7
Ribonuclease P protein subunit p20

6

1

High-throughput

0.948

High

1005809

RPP30
Ribonuclease P protein subunit p30

4

1

High-throughput

0.697

High

342445

RPP29
Ribonuclease P protein subunit p29

4

1

High-throughput

0.691

High

447218

NPM
Nucleophosmin

3

3

High-throughput

0.667

High

1239124

NEPRO
Nucleolus and neural progenitor protein

3

1

High-throughput

0.650

High

1328039

RPP21
Ribonuclease P protein subunit p21

2

1

High-throughput

0.628

High

1328035

KLDC3
Kelch domain-containing protein 3

3

1

High-throughput

0.609

High

1181325

CR021
UPF0711 protein C18orf21

3

1

High-throughput

0.604

High

953938

IF4A1
Eukaryotic initiation factor 4A-I

2

0

High-throughput

0.602

High

294987

RPP40
Ribonuclease P protein subunit p40

2

1

High-throughput

0.601

High

325440

RPP14
Ribonuclease P protein subunit p14

2

1

High-throughput

0.601

High

1005747

RPP38
Ribonuclease P protein subunit p38

2

1

High-throughput

0.601

High

1328025

POP5
Ribonuclease P/MRP protein subunit POP5

2

2

High-throughput

0.601

High

1328033

POP1
Ribonucleases P/MRP protein subunit POP1

2

1

High-throughput

0.601

High

1150667

TRBP2
RISC-loading complex subunit TARBP2

2

0

High-throughput

0.576

High

1328046

DICER
Endoribonuclease Dicer

2

0

High-throughput

0.576

High

1126623

GRB7
Growth factor receptor-bound protein 7

2

0

High-throughput

0.547

High

51458

FSD2
Fibronectin type III and SPRY domain-containing protein 2

1

1

High-throughput

0.536

High

288702

NPM3
Nucleoplasmin-3

1

3

High-throughput

0.536

High

338902

CBX6
Chromobox protein homolog 6

1

1

High-throughput

0.536

High

431188

LA
Lupus La protein

1

2

High-throughput

0.536

High

1016516

SRSF3
Serine/arginine-rich splicing factor 3

1

5

High-throughput

0.536

High

1130785

RRP5
Protein RRP5 homolog

1

1

High-throughput

0.536

High

1156641

ENOX2
Ecto-NOX disulfide-thiol exchanger 2

1

1

High-throughput

0.536

High

1328020

ENOX1
Ecto-NOX disulfide-thiol exchanger 1

1

1

High-throughput

0.536

High

1328032

MPP8
M-phase phosphoprotein 8

1

1

High-throughput

0.536

High

1328034

RBM4B
RNA-binding protein 4B

1

3

High-throughput

0.536

High

1328037

RBM4
RNA-binding protein 4

1

3

High-throughput

0.536

High

1328044

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

1328019

PNMA1
Paraneoplastic antigen Ma1

1

1

High-throughput

0.523

High

1328028

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

1

High-throughput

0.523

High

1328043

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

1

High-throughput

0.523

High

920115

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.513

High

1027589

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.513

High

1104848

SNTB2
Beta-2-syntrophin

1

0

High-throughput

0.513

High

1113688

CUL3
Cullin-3

1

0

High-throughput

0.513

High

1328026

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

1228437

FTM
Protein fantom

1

2

High-throughput

0.489

High

372576

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

406389

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

1194215

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

1258347

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.479

High

352490

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

401139

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

831064

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

1024699

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1290587

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1328023

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1328029

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1328031

DNJC2
DnaJ homolog subfamily C member 2

1

0

High-throughput

0.458

High

1328042

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1328045

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

1328027

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

124943

GTPB1
GTP-binding protein 1

1

0

High-throughput

0.426

High

1328024

ARHG2
Rho guanine nucleotide exchange factor 2

6

0

High-throughput

0.383

High

1328040

IBTK
Inhibitor of Bruton tyrosine kinase

4

0

High-throughput

0.360

High

1199004

KLH12
Kelch-like protein 12

3

0

High-throughput

0.352

High

193889

RGS5
Regulator of G-protein signaling 5

1

0

High-throughput

0.279

Low

607702

DCAM
S-adenosylmethionine decarboxylase proenzyme

1

0

High-throughput

0.279

Low

702406

CYTD
Cystatin-D

1

0

High-throughput

0.279

Low

1127429

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1328036

FEM1A
Protein fem-1 homolog A

1

0

High-throughput

0.279

Low

1328041

CTNL1
Alpha-catulin

1

0

High-throughput

0.279

Low

1328048

DTNA
Dystrobrevin alpha

1

0

High-throughput

0.279

Low

210587

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

0

High-throughput

0.249

Low

273078

CLU
Clustered mitochondria protein homolog

1

0

High-throughput

0.249

Low

273355

NPHP4
Nephrocystin-4

1

0

High-throughput

0.249

Low

1087672

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

0

High-throughput

0.249

Low

1217438

GKAP1
G kinase-anchoring protein 1

1

0

High-throughput

0.249

Low

1295489

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.249

Low

1328021

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.249

Low

1328038

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

227111

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

869288

XDH
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase

1

0

High-throughput

0.232

Low

1217539

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

0

High-throughput

0.232

Low

1328022

PXDN
Peroxidasin homolog

1

0

High-throughput

0.232

Low

1328030

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low

1328047

NISCH
Nischarin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025