HitPredict

Interactor 1: SMC3 (O42649)
Structural maintenance of chromosomes protein 3 (Cohesin complex Psm3 subunit)
Gene: psm3

Interactor 2: PDS5 (Q9HFF5)
Sister chromatid cohesion protein pds5 (Precocious dissociation of sisters protein 5)
Gene: PDS5

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26687354
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0007064 - mitotic sister chromatid cohesion GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1194 Sp			1 1205
+	Mm
		93885 SMC3_MOUSE (1-1193): 7.92e-96: 335: 38.23		E9QPI5_MOUSE (11-1196): 0: 1226: 21.56
+	Hs
		1100586 SMC3_HUMAN (1-1193): 1.2e-95: 334: 38.23		PDS5A_HUMAN (11-1194): 0: 1221: 21.43
+	Hs
		1345702 SMC3_HUMAN (1-1193): 1.2e-95: 334: 38.23		PDS5B_HUMAN (11-1202): 0: 1213: 21.92
+	Xl
		292739 SMC3_XENLA (1-1193): 3.47e-98: 341: 37.76		PD5AA_XENLA (7-1200): 0: 1201: 21.07
+	Xl
		1117310 Q8AW91_XENLA (1-1193): 9.49e-98: 340: 37.66		PD5AB_XENLA (10-1200): 0: 1201: 21.12
+	Xl
		292740 SMC3_XENLA (1-1193): 3.47e-98: 341: 37.76		PD5BB_XENLA (11-1201): 0: 1186: 21.75
+	Xl
		292738 SMC3_XENLA (1-1193): 3.47e-98: 341: 37.76		PD5BA_XENLA (11-1201): 0: 1173: 21.45
+	Xl
		1115499 Q8AW91_XENLA (1-1193): 9.49e-98: 340: 37.66		PD5BA_XENLA (11-1201): 0: 1173: 21.45
+	Mm
		93884 SMC1A_MOUSE (2-1183): 7.91e-77: 279: 16.52		E9QPI5_MOUSE (11-1196): 0: 1226: 21.56
+	Hs
		1057273 SMC1A_HUMAN (2-1183): 1.13e-76: 279: 16.52		PDS5A_HUMAN (11-1194): 0: 1221: 21.43
+	Mm
		1118817 SMC1A_MOUSE (2-1183): 7.91e-77: 279: 16.52		PDS5B_MOUSE (11-1202): 0: 1215: 21.96
+	Hs
		1057405 SMC1A_HUMAN (2-1183): 1.13e-76: 279: 16.52		PDS5B_HUMAN (11-1202): 0: 1213: 21.92
+	Mm
		1149127 SMC1A_MOUSE (2-1183): 7.91e-77: 279: 16.52		PDS5A_MOUSE (11-1196): 0: 1208: 21.48
+	Xl
		292729 SMC1A_XENLA (2-1183): 1.34e-71: 263: 16.93		PD5AB_XENLA (10-1200): 0: 1201: 21.12
+	Xl
		292730 SMC1A_XENLA (2-1183): 1.34e-71: 263: 16.93		PD5AA_XENLA (7-1200): 0: 1201: 21.07
+	Sp
		293288 SMC1_SCHPO (2-1186): 1.82e-66: 248: 15.19		PDS5_SCHPO (1-1205): 0: 1212: 100.00
+	Xl
		292728 SMC1A_XENLA (2-1183): 1.34e-71: 263: 16.93		PD5BA_XENLA (11-1201): 0: 1173: 21.45
+	Sc
		810772 SMC3_YEAST (1-1194): 7.3e-82: 294: 33.20		PDS5_YEAST (3-1197): 0: 976: 22.33
+	Sc
		700799 SMC1_YEAST (2-1186): 2e-63: 238: 16.84		PDS5_YEAST (3-1197): 0: 976: 22.33
+	Hs
		69118 SMC1A_HUMAN (2-1183): 1.13e-76: 279: 16.52		A9IYQ1_HUMAN (1028-1202): 1.69e-36: 142: 23.44