Protein: EPN4
Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR)

Gene: EPN4, CLINT1
Organism: Homo sapiens
Interactions: 207
UniProt ID: Q14677

Gene Ontology (top 5):
GO:0005543 - phospholipid binding
GO:0005654 - nucleoplasm
GO:0005768 - endosome
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1036403

PICAL
Phosphatidylinositol-binding clathrin assembly protein

3

12

High-throughput

0.871

High

1057127

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

3

High-throughput

0.866

High

1057132

GGA2
ADP-ribosylation factor-binding protein GGA2

4

7

Small-scale

0.698

High

1014011

AP1B1
AP-1 complex subunit beta-1

4

20

Small-scale

0.696

High

880411

AP1S2
AP-1 complex subunit sigma-2

3

4

High-throughput

0.675

High

317727

STABP
STAM-binding protein

3

1

High-throughput

0.671

High

1057083

STALP
AMSH-like protease

3

1

High-throughput

0.671

High

321545

AP2A1
AP-2 complex subunit alpha-1

3

20

Small-scale

0.670

High

1057074

SMAP2
Stromal membrane-associated protein 2

3

2

High-throughput

0.667

High

1057080

AP2M1
AP-2 complex subunit mu

3

5

High-throughput

0.667

High

451676

CLCB
Clathrin light chain B

3

8

High-throughput

0.656

High

212629

AP1G1
AP-1 complex subunit gamma-1

3

20

Small-scale

0.651

High

925867

AP2B1
AP-2 complex subunit beta

3

20

Small-scale

0.651

High

960794

CLH1
Clathrin heavy chain 1

3

13

Small-scale

0.651

High

1057041

EPN4
Clathrin interactor 1

1

7

Small-scale

0.647

High

128853

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

2

1

High-throughput

0.628

High

164894

SC16A
Protein transport protein Sec16A

2

8

High-throughput

0.628

High

302148

AP2A2
AP-2 complex subunit alpha-2

2

20

High-throughput

0.628

High

863938

CLH2
Clathrin heavy chain 2

2

13

High-throughput

0.628

High

928298

DYL1
Dynein light chain 1, cytoplasmic

2

5

High-throughput

0.628

High

1057045

RBP1
RalA-binding protein 1

2

4

High-throughput

0.628

High

1057075

STON2
Stonin-2

2

5

High-throughput

0.628

High

1057081

REPS1
RalBP1-associated Eps domain-containing protein 1

2

20

High-throughput

0.628

High

1057097

DNJC7
DnaJ homolog subfamily C member 7

2

6

High-throughput

0.628

High

1057108

CSTFT
Cleavage stimulation factor subunit 2 tau variant

2

2

High-throughput

0.628

High

1057135

STX8
Syntaxin-8

2

4

High-throughput

0.628

High

1057120

BMP2K
BMP-2-inducible protein kinase

3

6

Small-scale

0.625

High

451438

CLCA
Clathrin light chain A

2

8

High-throughput

0.611

High

885371

LOXL3
Lysyl oxidase homolog 3

2

2

High-throughput

0.611

High

1057112

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

2

11

Small-scale

0.611

High

1057119

ANLN
Anillin

2

1

High-throughput

0.611

High

261661

VAMP4
Vesicle-associated membrane protein 4

2

0

High-throughput

0.602

High

1057131

RABX5
Rab5 GDP/GTP exchange factor

2

0

High-throughput

0.602

High

205395

TGON2
Trans-Golgi network integral membrane protein 2

2

7

High-throughput

0.588

High

1057105

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

11

High-throughput

0.586

High

1057109

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

11

High-throughput

0.586

High

227461

PRKN
E3 ubiquitin-protein ligase parkin

2

14

High-throughput

0.584

High

552729

RFA2
Replication protein A 32 kDa subunit

2

4

High-throughput

0.584

High

591849

RAB4A
Ras-related protein Rab-4A

2

2

High-throughput

0.584

High

651209

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

3

High-throughput

0.584

High

720470

RFA3
Replication protein A 14 kDa subunit

2

3

High-throughput

0.584

High

912904

ARF6
ADP-ribosylation factor 6

2

5

High-throughput

0.584

High

914074

RB11A
Ras-related protein Rab-11A

2

2

High-throughput

0.584

High

1057091

MA7D2
MAP7 domain-containing protein 2

2

7

High-throughput

0.574

High

253743

AUXI
Auxilin

1

4

High-throughput

0.536

High

369608

ESR1
Estrogen receptor

1

20

High-throughput

0.536

High

529123

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

557693

NCK1
SH2/SH3 adapter protein NCK1

1

10

High-throughput

0.536

High

598121

FLNA
Filamin-A

1

2

High-throughput

0.536

High

609863

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

3

High-throughput

0.536

High

653975

MAP4
Microtubule-associated protein 4

1

10

High-throughput

0.536

High

724832

MYH9
Myosin-9

1

1

High-throughput

0.536

High

809306

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

6

High-throughput

0.536

High

844522

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.536

High

906456

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

3

High-throughput

0.536

High

1041582

CUL3
Cullin-3

1

2

High-throughput

0.536

High

1057048

DREB
Drebrin

1

3

High-throughput

0.536

High

1057058

SCYL2
SCY1-like protein 2

1

2

High-throughput

0.536

High

1057070

SYNPO
Synaptopodin

1

5

High-throughput

0.536

High

1057077

MY18A
Unconventional myosin-XVIIIa

1

2

High-throughput

0.536

High

1057078

TFG
Protein TFG

1

6

High-throughput

0.536

High

1057084

DYL2
Dynein light chain 2, cytoplasmic

1

5

High-throughput

0.536

High

1057093

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.536

High

1057094

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.536

High

1057103

WNK3
Serine/threonine-protein kinase WNK3

1

1

High-throughput

0.536

High

1057111

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

1

High-throughput

0.536

High

1057129

LIMA1
LIM domain and actin-binding protein 1

1

2

High-throughput

0.536

High

1057073

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.518

High

203938

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

275004

RENR
Renin receptor

1

0

High-throughput

0.513

High

813030

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

901672

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.513

High

1057060

MBOA1
Lysophospholipid acyltransferase 1

1

0

High-throughput

0.513

High

1057116

CPNE5
Copine-5

1

0

High-throughput

0.513

High

306176

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

11

High-throughput

0.501

High

402008

JUN
Transcription factor Jun

1

5

Small-scale

0.501

High

787913

EPS15
Epidermal growth factor receptor substrate 15

1

20

Small-scale

0.501

High

891148

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

11

High-throughput

0.501

High

1057102

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

1

11

High-throughput

0.501

High

1057100

OSB10
Oxysterol-binding protein-related protein 10

1

0

High-throughput

0.493

High

522614

MYH7
Myosin-7

1

1

High-throughput

0.489

High

796082

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.489

High

945771

M3K9
Mitogen-activated protein kinase kinase kinase 9

1

1

High-throughput

0.489

High

1057052

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

1

High-throughput

0.489

High

1057088

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

1057090

ARX
Homeobox protein ARX

1

10

High-throughput

0.489

High

1057092

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

1057115

PAAT
ATPase PAAT

1

3

High-throughput

0.489

High

1057138

MB212
Protein mab-21-like 2

1

1

High-throughput

0.489

High

983375

DYN1
Dynamin-1

1

0

Small-scale

0.480

High

120441

RHOD
Rho-related GTP-binding protein RhoD

1

13

High-throughput

0.479

High

160566

AURKA
Aurora kinase A

1

3

High-throughput

0.479

High

161657

GAK
Cyclin-G-associated kinase

1

7

High-throughput

0.479

High

162745

XPO1
Exportin-1

1

7

High-throughput

0.479

High

169459

BET1
BET1 homolog

1

4

High-throughput

0.479

High

178535

STX7
Syntaxin-7

1

4

High-throughput

0.479

High

212833

STX6
Syntaxin-6

1

4

High-throughput

0.479

High

232883

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

2

High-throughput

0.479

High

308712

KI20A
Kinesin-like protein KIF20A

1

7

High-throughput

0.479

High

322632

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

350174

RASK
GTPase KRas

1

10

High-throughput

0.479

High

374236

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

384843

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.479

High

397968

ISG15
Ubiquitin-like protein ISG15

1

16

High-throughput

0.479

High

434196

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

19

High-throughput

0.479

High

497022

TAU
Microtubule-associated protein tau

1

11

High-throughput

0.479

High

507020

LAMP1
Lysosome-associated membrane glycoprotein 1

1

5

High-throughput

0.479

High

508002

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

521933

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

527455

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.479

High

574677

ARF4
ADP-ribosylation factor 4

1

5

High-throughput

0.479

High

601512

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.479

High

607969

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

668686

PML
Protein PML

1

10

High-throughput

0.479

High

670028

MARCS
Myristoylated alanine-rich C-kinase substrate

1

4

High-throughput

0.479

High

684723

STIP1
Stress-induced-phosphoprotein 1

1

5

High-throughput

0.479

High

776115

ARL1
ADP-ribosylation factor-like protein 1

1

6

High-throughput

0.479

High

808610

YAP1
Transcriptional coactivator YAP1

1

12

High-throughput

0.479

High

845481

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

872443

EPHA5
Ephrin type-A receptor 5

1

4

High-throughput

0.479

High

881507

ARL4C
ADP-ribosylation factor-like protein 4C

1

8

High-throughput

0.479

High

884490

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.479

High

897360

ARF3
ADP-ribosylation factor 3

1

5

High-throughput

0.479

High

908543

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

950492

ARF1
ADP-ribosylation factor 1

1

5

High-throughput

0.479

High

950613

ARF5
ADP-ribosylation factor 5

1

5

High-throughput

0.479

High

959419

VIGLN
Vigilin

1

2

High-throughput

0.479

High

967174

EWS
RNA-binding protein EWS

1

2

High-throughput

0.479

High

982013

1433F
14-3-3 protein eta

1

11

High-throughput

0.479

High

998711

EP300
Histone acetyltransferase p300

1

8

High-throughput

0.479

High

1016176

FOXO1
Forkhead box protein O1

1

4

High-throughput

0.479

High

1024332

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

1

High-throughput

0.479

High

1026410

RFA4
Replication protein A 30 kDa subunit

1

4

High-throughput

0.479

High

1057043

TNIP1
TNFAIP3-interacting protein 1

1

10

High-throughput

0.479

High

1057044

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1057046

EPHA7
Ephrin type-A receptor 7

1

2

High-throughput

0.479

High

1057047

NTRK3
NT-3 growth factor receptor

1

13

High-throughput

0.479

High

1057050

ODFP2
Outer dense fiber protein 2

1

3

High-throughput

0.479

High

1057053

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.479

High

1057055

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

1057057

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

3

High-throughput

0.479

High

1057062

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

1057064

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1057066

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

1057067

SLX4
Structure-specific endonuclease subunit SLX4

1

6

High-throughput

0.479

High

1057068

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

1057069

RHG18
Rho GTPase-activating protein 18

1

3

High-throughput

0.479

High

1057071

ARL14
ADP-ribosylation factor-like protein 14

1

6

High-throughput

0.479

High

1057072

BICD2
Protein bicaudal D homolog 2

1

12

High-throughput

0.479

High

1057079

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.479

High

1057082

RNF31
E3 ubiquitin-protein ligase RNF31

1

6

High-throughput

0.479

High

1057085

BICD1
Protein bicaudal D homolog 1

1

7

High-throughput

0.479

High

1057086

AURKB
Aurora kinase B

1

3

High-throughput

0.479

High

1057087

MYO19
Unconventional myosin-XIX

1

5

High-throughput

0.479

High

1057095

RING2
E3 ubiquitin-protein ligase RING2

1

7

High-throughput

0.479

High

1057099

CP250
Centrosome-associated protein CEP250

1

6

High-throughput

0.479

High

1057101

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.479

High

1057106

WWTR1
WW domain-containing transcription regulator protein 1

1

11

High-throughput

0.479

High

1057110

RAB1B
Ras-related protein Rab-1B

1

1

High-throughput

0.479

High

1057113

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.479

High

1057123

GTSE1
G2 and S phase-expressed protein 1

1

4

High-throughput

0.479

High

1057126

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1057128

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1057130

UBQL2
Ubiquilin-2

1

9

High-throughput

0.479

High

1057134

MYO6
Unconventional myosin-VI

1

4

Small-scale

0.479

High

1057136

SMAG1
Protein Smaug homolog 1

1

1

High-throughput

0.479

High

1057137

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

231521

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.470

High

281626

WFS1
Wolframin

1

1

High-throughput

0.470

High

233452

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

541253

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

0

High-throughput

0.458

High

758233

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.458

High

813475

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

1035736

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1057049

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.458

High

1057054

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.458

High

1057059

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1057076

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

1057089

FMNL2
Formin-like protein 2

1

0

High-throughput

0.458

High

1057107

SHRPN
Sharpin

1

0

Small-scale

0.458

High

1057114

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1057117

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

1057118

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.458

High

1057125

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

82343

B9A025
Lysyl oxidase homolog

1

2

High-throughput

0.445

High

102401

G3V2R1
Sterile alpha motif domain containing 4A

1

1

High-throughput

0.445

High

717824

BMI1
Polycomb complex protein BMI-1

1

8

High-throughput

0.445

High

1043795

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.445

High

1057042

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

1057056

PKHA7
Pleckstrin homology domain-containing family A member 7

1

14

High-throughput

0.445

High

1057096

ZBT18
Zinc finger and BTB domain-containing protein 18

1

1

High-throughput

0.445

High

1057104

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

1049027

TRI14
Tripartite motif-containing protein 14

1

6

High-throughput

0.437

High

1057061

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.437

High

1057063

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.437

High

1057065

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

1057122

ARL15
ADP-ribosylation factor-like protein 15

1

6

High-throughput

0.437

High

1057139

ARL5A
ADP-ribosylation factor-like protein 5A

1

7

High-throughput

0.437

High

968140

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.426

High

1057051

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.426

High

831327

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.408

High

1057124

GGA3
ADP-ribosylation factor-binding protein GGA3

1

8

Small-scale

0.408

High

1057133

GGA1
ADP-ribosylation factor-binding protein GGA1

1

7

Small-scale

0.408

High

1057098

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.279

Low

1057121

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

1057140

CCD61
Centrosomal protein CCDC61

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024