HitPredict

Interactor 1: ACTN2 (Q9JI91)
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)
Gene: ACTN2

Interactor 2: ACTN2 (Q9JI91)
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)
Gene: ACTN2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29199018
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, CH~EF-hand_7, CH~EFhand_Ca_insen, CH~Spectrin, EF-hand_7~EF-hand_7, EF-hand_7~EFhand_Ca_insen, EF-hand_7~Spectrin, EFhand_Ca_insen~EFhand_Ca_insen, EFhand_Ca_insen~Spectrin, Spectrin~Spectrin
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005509 - calcium ion binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005865 - striated muscle thin filament
GO:0005925 - focal adhesion
and 32 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 894
Mm

1 894
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Last updated: 11Aug2025