Protein: LFA3
Lymphocyte function-associated antigen 3 (Ag3) (Surface glycoprotein LFA-3) (CD antigen CD58)

Gene: LFA3, CD58
Organism: Homo sapiens
Interactions: 28
UniProt ID: P19256

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0009986 - cell surface
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

125219

LEG9
Galectin-9

4

3

High-throughput

0.691

High

609569

LEG3
Galectin-3

4

3

High-throughput

0.691

High

127274

LEG8
Galectin-8

3

3

High-throughput

0.667

High

445475

CD2
T-cell surface antigen CD2

2

0

Small-scale

0.592

High

395466

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

619307

DNJA1
DnaJ homolog subfamily A member 1

1

0

High-throughput

0.518

High

619312

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.518

High

212929

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.513

High

431700

ITB1
Integrin beta-1

1

0

High-throughput

0.493

High

421471

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

362746

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

410608

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

High-throughput

0.479

High

217813

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

619309

BASI
Basigin

1

0

High-throughput

0.458

High

619316

TXND5
Thioredoxin domain-containing protein 5

1

0

High-throughput

0.458

High

619318

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.458

High

619314

LEG9C
Galectin-9C

1

3

High-throughput

0.437

High

619317

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

563163

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

619315

AB12B
Protein ABHD12B

3

0

High-throughput

0.342

High

619308

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.279

Low

619321

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.279

Low

371128

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

619310

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

619311

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.249

Low

619313

MIDN
Midnolin

1

0

High-throughput

0.249

Low

619320

FUT9
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9

1

0

High-throughput

0.249

Low

619319

PARP2
Poly [ADP-ribose] polymerase 2

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025