Protein: FCL
GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1)

Gene: FCL, GFUS
Organism: Homo sapiens
Interactions: 21
UniProt ID: Q13630

Gene Ontology (top 5):
GO:0001913 - T cell mediated cytotoxicity
GO:0005829 - cytosol
GO:0007159 - leukocyte cell-cell adhesion
GO:0009055 - electron transfer activity
GO:0010595 - positive regulation of endothelial cell migration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1116184

FCL
GDP-L-fucose synthase

3

15

Small-scale

0.849

High

944800

PCBP3
Poly(rC)-binding protein 3

3

0

High-throughput

0.629

High

1023770

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.536

High

1036514

ID2
DNA-binding protein inhibitor ID-2

1

0

High-throughput

0.518

High

1116190

RIOK2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.518

High

602783

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

943046

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

507945

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.501

High

1116191

TB22B
TBC1 domain family member 22B

1

1

High-throughput

0.489

High

861600

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.480

High

241625

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

347691

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.479

High

872309

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

1116188

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1116189

KLH15
Kelch-like protein 15

1

2

High-throughput

0.470

High

1116186

CLVS2
Clavesin-2

1

1

High-throughput

0.470

High

537122

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

1116185

KEAP1
Kelch-like ECH-associated protein 1

1

1

High-throughput

0.445

High

1116187

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.445

High

325315

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025