Protein: KMT5B
Histone-lysine N-methyltransferase KMT5B (Lysine N-methyltransferase 5B) (Lysine-specific methyltransferase 5B) (Suppressor of variegation 4-20 homolog 1) (Su(var)4-20 homolog 1) (Suv4-20h1) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.361)

Gene: KMT5B
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q4FZB7

Gene Ontology (top 5):
GO:0000779 - condensed chromosome, centromeric region
GO:0001650 - fibrillar center
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

979757

H4
Histone H4

2

5

Small-scale

0.778

High

1194048

MIB1
E3 ubiquitin-protein ligase MIB1

1

1

High-throughput

0.618

High

1194047

KMT5B
Histone-lysine N-methyltransferase KMT5B

1

0

Small-scale

0.614

High

1091410

ANK3
Ankyrin-3

1

0

High-throughput

0.586

High

260043

BRD4
Bromodomain-containing protein 4

2

3

High-throughput

0.584

High

1194051

TSYL2
Testis-specific Y-encoded-like protein 2

2

0

High-throughput

0.580

High

691066

1433T
14-3-3 protein theta

1

2

High-throughput

0.515

High

990291

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.515

High

342206

BRD1
Bromodomain-containing protein 1

1

0

Small-scale

0.513

High

884593

SYCC
Cysteine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

1194052

MOB1A
MOB kinase activator 1A

1

0

High-throughput

0.513

High

1194054

OGDHL
2-oxoglutarate dehydrogenase-like, mitochondrial

1

0

High-throughput

0.513

High

1194055

GRIP1
Glutamate receptor-interacting protein 1

1

0

Small-scale

0.504

High

1194050

H4G
Histone H4-like protein type G

1

5

Small-scale

0.501

High

396241

ESR1
Estrogen receptor

1

0

Small-scale

0.480

High

674189

BRD2
Bromodomain-containing protein 2

1

3

High-throughput

0.479

High

966394

1433G
14-3-3 protein gamma

1

2

High-throughput

0.479

High

1141151

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.479

High

1194053

HERC5
E3 ISG15--protein ligase HERC5

1

1

High-throughput

0.470

High

1194049

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

0

High-throughput

0.460

High

610352

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

1045356

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1144820

RABE1
Rab GTPase-binding effector protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025