Protein: PHF1
PHD finger protein 1 (Protein PHF1) (hPHF1) (Polycomb-like protein 1) (hPCl1)

Gene: PHF1
Organism: Homo sapiens
Interactions: 162
UniProt ID: O43189

Gene Ontology (top 5):
GO:0001222 - transcription corepressor binding
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

198032

RBPMS
RNA-binding protein with multiple splicing

4

0

High-throughput

0.864

High

198001

PHF19
PHD finger protein 19

2

10

High-throughput

0.789

High

198027

DPF1
Zinc finger protein neuro-d4

2

13

High-throughput

0.783

High

197991

EZH2
Histone-lysine N-methyltransferase EZH2

15

20

Small-scale

0.763

High

197988

SUZ12
Polycomb protein SUZ12

10

6

Small-scale

0.756

High

197938

MTA2
Metastasis-associated protein MTA2

2

9

Small-scale

0.754

High

197979

MTA1
Metastasis-associated protein MTA1

2

9

Small-scale

0.754

High

198050

MTA3
Metastasis-associated protein MTA3

2

9

Small-scale

0.754

High

197934

EED
Polycomb protein EED

7

13

Small-scale

0.748

High

197993

RBBP7
Histone-binding protein RBBP7

6

14

Small-scale

0.733

High

198028

EZH1
Histone-lysine N-methyltransferase EZH1

4

20

Small-scale

0.699

High

198047

DHB14
17-beta-hydroxysteroid dehydrogenase 14

4

1

High-throughput

0.698

High

197941

P53
Cellular tumor antigen p53

4

2

Small-scale

0.694

High

197973

RBBP4
Histone-binding protein RBBP4

4

14

Small-scale

0.694

High

197990

NAB2
NGFI-A-binding protein 2

4

0

High-throughput

0.668

High

198063

THAP1
THAP domain-containing protein 1

3

3

High-throughput

0.667

High

62811

EPOP
Elongin BC and Polycomb repressive complex 2-associated protein

3

9

High-throughput

0.667

High

198037

LCOR
Ligand-dependent corepressor

3

2

High-throughput

0.667

High

198035

ZBT10
Zinc finger and BTB domain-containing protein 10

3

2

High-throughput

0.665

High

198018

BOLL
Protein boule-like

2

0

High-throughput

0.655

High

197975

TFCP2
Alpha-globin transcription factor CP2

2

2

High-throughput

0.640

High

198061

PDLI7
PDZ and LIM domain protein 7

2

2

High-throughput

0.628

High

197992

DDB1
DNA damage-binding protein 1

2

1

Small-scale

0.619

High

197926

PHF1
PHD finger protein 1

1

10

Small-scale

0.618

High

197976

BPTF
Nucleosome-remodeling factor subunit BPTF

1

11

High-throughput

0.618

High

197977

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

9

High-throughput

0.618

High

197986

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

9

High-throughput

0.618

High

198029

JARD2
Protein Jumonji

1

9

High-throughput

0.618

High

198075

MTF2
Metal-response element-binding transcription factor 2

1

10

High-throughput

0.618

High

197928

ZN500
Zinc finger protein 500

2

1

High-throughput

0.606

High

197943

ZN688
Zinc finger protein 688

2

1

High-throughput

0.606

High

197958

LBX1
Transcription factor LBX1

2

3

High-throughput

0.606

High

197959

FOSB
Protein FosB

2

2

High-throughput

0.606

High

197966

ARI5A
AT-rich interactive domain-containing protein 5A

2

7

High-throughput

0.606

High

197967

ZBT16
Zinc finger and BTB domain-containing protein 16

2

1

High-throughput

0.606

High

197983

FHL2
Four and a half LIM domains protein 2

2

5

High-throughput

0.606

High

198004

TENS2
Tensin-2

2

2

High-throughput

0.606

High

198005

K1C40
Keratin, type I cytoskeletal 40

2

1

High-throughput

0.606

High

198007

MORN3
MORN repeat-containing protein 3

2

1

High-throughput

0.606

High

198041

TOX2
TOX high mobility group box family member 2

2

1

High-throughput

0.606

High

198049

LZTS2
Leucine zipper putative tumor suppressor 2

2

2

High-throughput

0.606

High

198057

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

1

High-throughput

0.606

High

198062

DISC1
Disrupted in schizophrenia 1 protein

2

1

High-throughput

0.606

High

198069

ZRAN1
Ubiquitin thioesterase ZRANB1

2

3

High-throughput

0.606

High

198077

MAGD1
Melanoma-associated antigen D1

2

1

High-throughput

0.606

High

197963

H31
Histone H3.1

2

8

Small-scale

0.602

High

197953

TRI23
E3 ubiquitin-protein ligase TRIM23

2

0

High-throughput

0.601

High

198034

BIRC7
Baculoviral IAP repeat-containing protein 7

2

0

High-throughput

0.601

High

197994

H31T
Histone H3.1t

1

8

Small-scale

0.586

High

197933

SAP30
Histone deacetylase complex subunit SAP30

2

1

Small-scale

0.584

High

197980

HDAC1
Histone deacetylase 1

2

4

Small-scale

0.584

High

197996

ARI4B
AT-rich interactive domain-containing protein 4B

2

4

Small-scale

0.584

High

198026

HDAC2
Histone deacetylase 2

2

4

Small-scale

0.584

High

198042

SIN3A
Paired amphipathic helix protein Sin3a

2

2

Small-scale

0.584

High

146435

BHE40
Class E basic helix-loop-helix protein 40

2

0

High-throughput

0.580

High

197930

VINEX
Vinexin

2

0

High-throughput

0.580

High

197970

TLE5
TLE family member 5

2

0

High-throughput

0.580

High

197974

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

198003

IKBP1
Interleukin-1 receptor-associated kinase 1-binding protein 1

2

0

High-throughput

0.580

High

198009

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.580

High

198022

ZN526
Zinc finger protein 526

2

0

High-throughput

0.580

High

198031

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.580

High

198043

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.580

High

198044

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

198046

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.580

High

198052

SMG9
Nonsense-mediated mRNA decay factor SMG9

2

0

High-throughput

0.580

High

198060

ZNF71
Endothelial zinc finger protein induced by tumor necrosis factor alpha

2

0

High-throughput

0.580

High

198065

ABI2
Abl interactor 2

2

0

High-throughput

0.580

High

198066

ZIM2
Zinc finger imprinted 2

2

0

High-throughput

0.580

High

198068

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.580

High

197981

CUL4B
Cullin-4B

2

2

Small-scale

0.571

High

153498

ANM5
Protein arginine N-methyltransferase 5

1

2

Small-scale

0.561

High

197961

H4
Histone H4

1

4

Small-scale

0.561

High

198033

ARRD3
Arrestin domain-containing protein 3

2

1

High-throughput

0.553

High

197984

HIC1
Hypermethylated in cancer 1 protein

1

2

Small-scale

0.552

High

197972

VAC14
Protein VAC14 homolog

1

0

High-throughput

0.549

High

197978

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.549

High

197931

DJC13
DnaJ homolog subfamily C member 13

1

1

High-throughput

0.536

High

197935

WDHD1
WD repeat and HMG-box DNA-binding protein 1

1

6

High-throughput

0.536

High

197955

TCPQ
T-complex protein 1 subunit theta

1

1

High-throughput

0.536

High

197957

ZN131
Zinc finger protein 131

1

1

High-throughput

0.536

High

198073

DICER
Endoribonuclease Dicer

1

1

High-throughput

0.536

High

198072

AT7L1
Ataxin-7-like protein 1

1

4

High-throughput

0.523

High

197968

Q05BL1
TP53BP2 protein

1

2

High-throughput

0.515

High

198006

Q6FHY5
MEOX2 protein

1

3

High-throughput

0.515

High

197949

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.513

High

197952

DEK
Protein DEK

1

0

High-throughput

0.513

High

197989

TRBP2
RISC-loading complex subunit TARBP2

1

0

High-throughput

0.513

High

198008

BORA
Protein aurora borealis

1

0

High-throughput

0.513

High

198038

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

0

High-throughput

0.513

High

198045

MIPEP
Mitochondrial intermediate peptidase

1

0

High-throughput

0.513

High

198058

NEK6
Serine/threonine-protein kinase Nek6

1

0

Small-scale

0.504

High

197964

PR20D
Proline-rich protein 20D

1

1

High-throughput

0.483

High

197954

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.481

High

197982

ASPP2
Apoptosis-stimulating of p53 protein 2

1

4

High-throughput

0.481

High

198016

HOMEZ
Homeobox and leucine zipper protein Homez

1

4

High-throughput

0.481

High

198025

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

198064

ZSC32
Zinc finger and SCAN domain-containing protein 32

1

1

High-throughput

0.481

High

146774

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

1

High-throughput

0.479

High

197927

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

9

High-throughput

0.479

High

197929

KDM1A
Lysine-specific histone demethylase 1A

1

3

Small-scale

0.479

High

197939

MBD3
Methyl-CpG-binding domain protein 3

1

3

High-throughput

0.479

High

197944

MYBB
Myb-related protein B

1

3

High-throughput

0.479

High

197945

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

Small-scale

0.479

High

197946

XRCC6
X-ray repair cross-complementing protein 6

1

1

Small-scale

0.479

High

197947

XRCC5
X-ray repair cross-complementing protein 5

1

1

Small-scale

0.479

High

197950

SMCA1
Probable global transcription activator SNF2L1

1

9

High-throughput

0.479

High

197969

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

Small-scale

0.479

High

197971

DHX9
ATP-dependent RNA helicase A

1

1

Small-scale

0.479

High

197987

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

13

High-throughput

0.479

High

197999

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

3

High-throughput

0.479

High

198002

LIN9
Protein lin-9 homolog

1

1

High-throughput

0.479

High

198010

AEBP2
Zinc finger protein AEBP2

1

5

High-throughput

0.479

High

198015

P66A
Transcriptional repressor p66-alpha

1

3

High-throughput

0.479

High

198017

BAP18
Chromatin complexes subunit BAP18

1

1

High-throughput

0.479

High

198021

HJURP
Holliday junction recognition protein

1

1

High-throughput

0.479

High

198023

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

198024

P66B
Transcriptional repressor p66-beta

1

3

High-throughput

0.479

High

198030

RAD50
DNA repair protein RAD50

1

2

Small-scale

0.479

High

198036

LIN37
Protein lin-37 homolog

1

1

High-throughput

0.479

High

198039

Z512B
Zinc finger protein 512B

1

3

High-throughput

0.479

High

198040

PWP2A
PWWP domain-containing protein 2A

1

3

High-throughput

0.479

High

198048

MEP50
Methylosome protein WDR77

1

7

Small-scale

0.479

High

198051

SP130
Histone deacetylase complex subunit SAP130

1

6

High-throughput

0.479

High

198053

BC11A
B-cell lymphoma/leukemia 11A

1

1

High-throughput

0.479

High

198056

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

3

High-throughput

0.479

High

198059

EXOS4
Exosome complex component RRP41

1

1

High-throughput

0.479

High

198067

MBD2
Methyl-CpG-binding domain protein 2

1

3

High-throughput

0.479

High

198070

HMGX4
HMG domain-containing protein 4

1

4

High-throughput

0.479

High

198071

LIMA1
LIM domain and actin-binding protein 1

1

1

Small-scale

0.479

High

198079

NCOA3
Nuclear receptor coactivator 3

1

2

Small-scale

0.479

High

197995

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

158708

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.458

High

197932

ZN217
Zinc finger protein 217

1

0

Small-scale

0.458

High

197948

DDX5
Probable ATP-dependent RNA helicase DDX5

1

0

Small-scale

0.458

High

197951

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

197960

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

Small-scale

0.458

High

197962

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.458

High

197985

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

Small-scale

0.458

High

197997

LIN52
Protein lin-52 homolog

1

0

High-throughput

0.458

High

198055

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

198074

GRIP1
Glutamate receptor-interacting protein 1

1

0

Small-scale

0.458

High

197965

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.439

High

197942

CALCA
Calcitonin gene-related peptide 1

1

1

High-throughput

0.437

High

197956

AFF2
AF4/FMR2 family member 2

1

5

Small-scale

0.437

High

198011

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

197940

CALC
Calcitonin [Cleaved into: Calcitonin; Katacalcin

1

1

High-throughput

0.407

High

198014

PRSR2
Proline and serine-rich protein 2

2

0

High-throughput

0.328

High

198012

K0408
Uncharacterized protein KIAA0408

2

0

High-throughput

0.320

High

62245

GG6L9
Golgin subfamily A member 6-like protein 9

2

0

High-throughput

0.316

High

197998

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

198000

AVPI1
Arginine vasopressin-induced protein 1

2

0

High-throughput

0.316

High

198013

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

2

0

High-throughput

0.316

High

198020

RB8NL
RBBP8 N-terminal-like protein

2

0

High-throughput

0.316

High

198054

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

2

0

High-throughput

0.316

High

197936

DYSF
Dysferlin

1

0

High-throughput

0.282

High

198019

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

1

0

High-throughput

0.279

Low

198076

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.279

Low

198078

S4A7
Sodium bicarbonate cotransporter 3

1

0

High-throughput

0.279

Low

100279

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

197937

NCTR1
Natural cytotoxicity triggering receptor 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024