HitPredict

Interactor 1: ACTC (P68033)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: Actc1

Interactor 2: RN138 (Q9CQE0)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: Rnf138

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36800290
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 377 Mm			1 245
+	Mm
		1295885 ACTBL_MOUSE (4-377): 0: 721: 89.57		RING2_MOUSE (2-188): 1.17e-31: 120: 19.68
+	Mm
		993113 ACTG_MOUSE (4-377): 0: 598: 94.39		RN138_MOUSE (1-245): 1.63e-58: 187: 100.00
+	Hs
		953211 ACTB_HUMAN (4-377): 0: 598: 94.12		TRAF6_HUMAN (12-245): 1.56e-34: 131: 17.08
+	Hs
		993398 ACTG_HUMAN (4-377): 0: 598: 94.39		TRAF6_HUMAN (12-245): 1.56e-34: 131: 17.08
+	Mm
		953232 ACTB_MOUSE (4-377): 0: 598: 94.12		TRAF6_MOUSE (12-227): 5.69e-34: 129: 17.33
+	Hs
		953029 ACTB_HUMAN (4-377): 0: 598: 94.12		RN125_HUMAN (2-245): 2.12e-35: 127: 27.05
+	Hs
		993302 ACTG_HUMAN (4-377): 0: 598: 94.39		RING2_HUMAN (2-188): 6.23e-32: 121: 19.68
+	Mm
		953287 ACTB_MOUSE (4-377): 0: 598: 94.12		RING2_MOUSE (2-188): 1.17e-31: 120: 19.68
+	Mm
		993115 ACTG_MOUSE (4-377): 0: 598: 94.39		RING2_MOUSE (2-188): 1.17e-31: 120: 19.68
+	Hs
		623266 ACTS_HUMAN (1-377): 0: 599: 98.94		RO52_HUMAN (3-151): 3.4e-30: 118: 14.38
+	Hs
		623217 ACTB_HUMAN (4-377): 0: 598: 94.12		RO52_HUMAN (3-151): 3.4e-30: 118: 14.38
+	Hs
		623263 ACTG_HUMAN (4-377): 0: 598: 94.39		RO52_HUMAN (3-151): 3.4e-30: 118: 14.38
+	Hs
		952786 ACTB_HUMAN (4-377): 0: 598: 94.12		TRI26_HUMAN (3-184): 7.74e-30: 118: 17.24
+	Hs
		623244 ACTA_HUMAN (1-377): 0: 597: 98.41		RO52_HUMAN (3-151): 3.4e-30: 118: 14.38
+	Hs
		996548 ACTS_HUMAN (1-377): 0: 599: 98.94		RAD18_HUMAN (7-245): 2.26e-27: 111: 12.00
+	Hs
		953133 ACTB_HUMAN (4-377): 0: 598: 94.12		RAD18_HUMAN (7-245): 2.26e-27: 111: 12.00
+	Hs
		952965 ACTB_HUMAN (4-377): 0: 598: 94.12		TRI58_HUMAN (3-181): 2.11e-26: 108: 14.58