Protein: CATO
Cathepsin O (EC 3.4.22.42)

Gene: CATO, CTSO
Organism: Homo sapiens
Interactions: 18
UniProt ID: P43234

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0005764 - lysosome
GO:0006508 - proteolysis
GO:0051603 - proteolysis involved in protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

370404

KNG1
Kininogen-1

3

15

High-throughput

0.861

High

370033

CYTC
Cystatin-C

1

15

High-throughput

0.691

High

370279

CYTA
Cystatin-A

1

8

High-throughput

0.691

High

402755

CYTB
Cystatin-B

1

8

High-throughput

0.691

High

705268

GRN
Progranulin

3

1

High-throughput

0.667

High

846118

DCAF6
DDB1- and CUL4-associated factor 6

1

1

High-throughput

0.489

High

846124

PGRP3
Peptidoglycan recognition protein 3

1

2

High-throughput

0.489

High

846115

1433G
14-3-3 protein gamma

1

1

High-throughput

0.470

High

846119

AMZ2
Archaemetzincin-2

1

0

High-throughput

0.458

High

288849

LYPA1
Acyl-protein thioesterase 1

3

0

High-throughput

0.347

High

332287

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.279

Low

846120

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.279

Low

846117

MTFR1
Mitochondrial fission regulator 1

1

0

High-throughput

0.269

Low

603200

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.268

Low

846116

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.268

Low

846121

LMO3
LIM domain only protein 3

1

0

High-throughput

0.268

Low

846123

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.268

Low

846122

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025