Protein: HNS
DNA-binding protein H-NS (Heat-stable nucleoid-structuring protein) (Histone-like protein HLP-II) (Protein B1) (Protein H1)

Gene: HNS
Organism: Escherichia coli K-12
Interactions: 71
UniProt ID: P0ACF8

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0001217 - DNA-binding transcription repressor activity
GO:0003680 - minor groove of adenine-thymine-rich DNA binding
GO:0003681 - bent DNA binding
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

467191

STPA
DNA-binding protein StpA

4

6

High-throughput

0.697

High

467190

HNS
DNA-binding protein H-NS

3

6

Small-scale

0.680

High

467219

CNU
OriC-binding nucleoid-associated protein

3

1

Small-scale

0.650

High

467094

DBHA
DNA-binding protein HU-alpha

2

1

High-throughput

0.588

High

467150

DBHB
DNA-binding protein HU-beta

2

1

High-throughput

0.588

High

462980

TIG
Trigger factor

2

0

High-throughput

0.563

High

467201

SECA
Protein translocase subunit SecA

2

0

High-throughput

0.563

High

467216

RL24
Large ribosomal subunit protein uL24

2

0

High-throughput

0.563

High

467222

NFI
Endonuclease V

2

0

High-throughput

0.563

High

467082

HHA
Hemolysin expression-modulating protein Hha

1

1

Small-scale

0.561

High

467200

SSB
Single-stranded DNA-binding protein

2

0

High-throughput

0.547

High

463377

UVRB
UvrABC system protein B

2

1

High-throughput

0.537

High

459662

KPRS
Ribose-phosphate pyrophosphokinase

1

1

High-throughput

0.536

High

463229

YEEN
Probable transcriptional regulatory protein YeeN

1

1

High-throughput

0.536

High

467221

YQCA
Flavodoxin YqcA

1

1

High-throughput

0.536

High

461377

RS12
Small ribosomal subunit protein uS12

1

0

High-throughput

0.513

High

463469

YQGF
Putative pre-16S rRNA nuclease

1

0

High-throughput

0.513

High

466137

YCED
Large ribosomal RNA subunit accumulation protein YceD

1

0

High-throughput

0.513

High

467196

RL14
Large ribosomal subunit protein uL14

1

0

High-throughput

0.513

High

467206

PEPT
Peptidase T

1

0

High-throughput

0.513

High

467208

YIIS
UPF0381 protein YiiS

1

0

High-throughput

0.513

High

467214

OBG
GTPase ObgE/CgtA

1

0

High-throughput

0.513

High

467218

FLAV
Flavodoxin 1

1

0

High-throughput

0.513

High

467192

ROB
Right origin-binding protein

1

1

High-throughput

0.500

High

467205

SCPA
Methylmalonyl-CoA mutase

1

1

High-throughput

0.489

High

467209

TORA
Trimethylamine-N-oxide reductase 1

1

1

High-throughput

0.489

High

467202

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.479

High

467204

MAK
Fructokinase

1

0

High-throughput

0.479

High

467210

TKT2
Transketolase 2

1

2

High-throughput

0.479

High

336969

PHSM
Maltodextrin phosphorylase

1

0

High-throughput

0.464

High

340919

DPO1
DNA polymerase I

1

0

High-throughput

0.464

High

368648

UVRD
DNA helicase II

1

0

High-throughput

0.464

High

415763

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.464

High

460282

PYRH
Uridylate kinase

1

0

High-throughput

0.464

High

463860

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.464

High

463946

RPOB
DNA-directed RNA polymerase subunit beta

1

0

High-throughput

0.464

High

466598

HOLE
DNA polymerase III subunit theta

1

0

High-throughput

0.464

High

467198

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.464

High

467203

MALQ
4-alpha-glucanotransferase

1

0

High-throughput

0.464

High

467217

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

467225

YNBC
Uncharacterized protein YnbC

1

0

High-throughput

0.464

High

343218

THRC
Threonine synthase

1

0

High-throughput

0.458

High

452029

PUTA
Bifunctional protein PutA [Includes: Proline dehydrogenase

1

0

High-throughput

0.458

High

460227

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.458

High

466685

EXBB
Biopolymer transport protein ExbB

1

0

High-throughput

0.458

High

467207

YAFC
Uncharacterized HTH-type transcriptional regulator YafC

1

0

High-throughput

0.458

High

467226

KDGR
HTH-type transcriptional regulator KdgR

1

0

High-throughput

0.458

High

467228

YFFS
Uncharacterized protein YffS

1

0

High-throughput

0.458

High

466768

FLIG
Flagellar motor switch protein FliG

1

1

Small-scale

0.437

High

467215

TORZ
Trimethylamine-N-oxide reductase 2

1

1

High-throughput

0.437

High

421197

PRIB
Primosomal replication protein N

1

0

High-throughput

0.279

Low

457199

YIDB
Uncharacterized protein YidB

1

0

High-throughput

0.279

Low

462776

RUVC
Crossover junction endodeoxyribonuclease RuvC

1

0

High-throughput

0.279

Low

467194

YEJG
Uncharacterized protein YejG

1

0

High-throughput

0.279

Low

467211

YCHJ
UPF0225 protein YchJ

1

0

High-throughput

0.279

Low

467223

SXY
Protein Sxy

1

0

High-throughput

0.279

Low

467224

VXIS
Prophage excisionase-like protein

1

0

High-throughput

0.279

Low

467229

PAAY
Phenylacetic acid degradation protein PaaY

1

0

High-throughput

0.279

Low

467230

YDJF
Uncharacterized HTH-type transcriptional regulator YdjF

1

0

High-throughput

0.279

Low

467199

YBBO
Uncharacterized oxidoreductase YbbO

1

0

High-throughput

0.261

Low

461781

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.253

Low

467197

CEDA
Cell division activator CedA

1

0

High-throughput

0.253

Low

367380

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.249

Low

404181

APAH
Bis(5'-nucleosyl)-tetraphosphatase [symmetrical]

1

0

High-throughput

0.249

Low

467193

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.249

Low

467195

NLPD
Murein hydrolase activator NlpD

1

0

High-throughput

0.249

Low

467212

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

467213

AG43
Antigen 43

1

0

High-throughput

0.249

Low

467220

YODD
Uncharacterized protein YodD

1

0

High-throughput

0.249

Low

467227

YEGH
UPF0053 protein YegH

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024