Interactor 1: CASP8 (O89110)
Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
Gene: CASP8

Interactor 2: IL1B (P10749)
Interleukin-1 beta (IL-1 beta)
Gene: IL1B

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.80 0.659

The method score is based on:

Property Details
Experiments 25607459, 18725521
Identification Methods affinity chromatography technology, protease assay
Interaction Type physical association, cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL1~Peptidase_C14
Common GO terms -
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 480
Mm

1 269
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025