Protein: TIM44
Mitochondrial import inner membrane translocase subunit TIM44 (Inner membrane import site protein 45) (ISP45) (Membrane import machinery protein MIM44) (Mitochondrial protein import protein 1)

Gene: TIM44
Organism: Saccharomyces cerevisiae S288C
Interactions: 61
UniProt ID: Q01852

Gene Ontology (top 5):
GO:0001405 - PAM complex, Tim23 associated import motor
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

699970

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

37

2

Small-scale

0.770

High

478445

HSP77
Import motor subunit, mitochondrial

23

3

Small-scale

0.767

High

792675

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

10

1

Small-scale

0.755

High

761886

TIM17
Mitochondrial import inner membrane translocase subunit TIM17

7

1

Small-scale

0.745

High

967653

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

6

3

Small-scale

0.726

High

750720

GRPE
GrpE protein homolog, mitochondrial

5

0

Small-scale

0.684

High

826171

TOM22
Mitochondrial import receptor subunit TOM22

4

0

Small-scale

0.648

High

860224

TIM21
Mitochondrial import inner membrane translocase subunit TIM21

3

0

Small-scale

0.628

High

967644

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

0

Small-scale

0.614

High

967645

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

2

1

Small-scale

0.584

High

494735

HSP72
Heat shock protein SSA2

2

1

Small-scale

0.571

High

705545

HSP78
Heat shock protein 78, mitochondrial

2

0

High-throughput

0.559

High

333598

CYB2
L-lactate dehydrogenase

2

0

Small-scale

0.547

High

588197

HSP60
Heat shock protein 60, mitochondrial

1

1

Small-scale

0.501

High

492157

HSP71
Heat shock protein SSA1

1

1

Small-scale

0.479

High

576003

ADT2
ADP,ATP carrier protein 2

1

2

Small-scale

0.479

High

628375

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

737200

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

967646

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

967650

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

5

Small-scale

0.479

High

967658

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

339796

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.458

High

357355

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

423897

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

649918

CDC15
Cell division control protein 15

1

0

High-throughput

0.458

High

864355

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

967647

PDR15
ATP-dependent permease PDR15

1

0

High-throughput

0.458

High

967649

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

633495

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

695324

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

766162

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.445

High

791142

MDJ2
Mitochondrial DnaJ homolog 2

1

3

Small-scale

0.445

High

663064

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

758694

TEM1
Protein TEM1

1

1

High-throughput

0.437

High

765933

SIT1
Siderophore iron transporter 1

1

1

High-throughput

0.437

High

865291

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

961461

CDC14
Tyrosine-protein phosphatase CDC14

1

1

High-throughput

0.437

High

967654

ENB1
Siderophore iron transporter ENB1

1

1

High-throughput

0.437

High

334781

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

715373

SPT7
Transcriptional activator SPT7

1

0

High-throughput

0.426

High

769214

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

382789

RL24A
Large ribosomal subunit protein eL24A

1

0

High-throughput

0.279

Low

700575

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.279

Low

837451

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.279

Low

558209

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

689286

SP110
Spindle pole body component 110

1

0

High-throughput

0.249

Low

692879

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

748174

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

762476

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

775824

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

967648

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

967651

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

967652

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

967657

UBX3
UBX domain-containing protein 3

1

0

High-throughput

0.238

Low

613743

RS3A2
Small ribosomal subunit protein eS1B

1

0

High-throughput

0.232

Low

757454

SPT8
Transcription factor SPT8

1

0

High-throughput

0.232

Low

829673

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.232

Low

866122

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.232

Low

967655

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

High-throughput

0.232

Low

967656

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024