Protein: TPIS
Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase)

Gene: TPIS, TPI1
Organism: Saccharomyces cerevisiae S288C
Interactions: 140
UniProt ID: P00942

Gene Ontology (top 5):
GO:0004807 - triose-phosphate isomerase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

343314

TPIS
Triosephosphate isomerase

4

6

Small-scale

0.893

High

343358

SIS1
Protein SIS1

4

1

High-throughput

0.678

High

343339

HSP71
Heat shock protein SSA1

3

2

High-throughput

0.624

High

343347

HSC82
ATP-dependent molecular chaperone HSC82

2

3

High-throughput

0.611

High

343402

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

343340

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.571

High

343371

HSP7F
Heat shock protein homolog SSE1

2

3

High-throughput

0.571

High

343417

FAR11
Factor arrest protein 11

2

0

High-throughput

0.563

High

343331

LTE1
Guanine nucleotide exchange factor LTE1

1

1

High-throughput

0.536

High

343352

GAP1
General amino-acid permease GAP1

1

0

Small-scale

0.529

High

343415

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

343422

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

343428

ACL4
Assembly chaperone of RPL4

1

0

High-throughput

0.513

High

343336

NFT1
ABC transporter NFT1

1

1

High-throughput

0.494

High

343416

RHO5
GTP-binding protein RHO5

1

1

Small-scale

0.481

High

334391

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.479

High

334564

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.479

High

334852

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.479

High

336643

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.479

High

342600

ENO1
Enolase 1

1

3

High-throughput

0.479

High

342797

ENO2
Enolase 2

1

3

High-throughput

0.479

High

343317

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.479

High

343325

SC160
Protein SCP160

1

1

High-throughput

0.479

High

343326

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

343332

FUMH
Fumarate hydratase, mitochondrial

1

1

High-throughput

0.479

High

343349

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.479

High

343355

HSP74
Heat shock protein SSA4

1

2

High-throughput

0.479

High

343368

PYC2
Pyruvate carboxylase 2

1

1

High-throughput

0.479

High

343381

MCM7
DNA replication licensing factor MCM7

1

1

High-throughput

0.479

High

343392

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.479

High

343393

HMF1
Protein HMF1

1

1

High-throughput

0.479

High

343395

MMF1
Protein MMF1, mitochondrial

1

1

High-throughput

0.479

High

343411

VID30
Vacuolar import and degradation protein 30

1

1

High-throughput

0.479

High

343421

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.479

High

343425

COFI
Cofilin

1

1

High-throughput

0.479

High

343426

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

343430

PUR8
Adenylosuccinate lyase

1

1

High-throughput

0.479

High

336170

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

Small-scale

0.458

High

339942

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.458

High

340565

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

343315

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.458

High

343316

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

343318

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

343319

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

343320

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

343321

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.458

High

343322

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

343323

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

343324

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

343327

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

343328

KAD2
Adenylate kinase

1

0

High-throughput

0.458

High

343329

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.458

High

343330

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

343333

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

343334

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

343335

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

343338

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

343342

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

343343

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

343345

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.458

High

343346

TAL1
Transaldolase

1

0

High-throughput

0.458

High

343348

STI1
Heat shock protein STI1

1

0

High-throughput

0.458

High

343351

PGTB1
Geranylgeranyl transferase type-1 subunit beta

1

0

High-throughput

0.458

High

343353

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.458

High

343354

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

343356

TKT1
Transketolase 1

1

0

High-throughput

0.458

High

343357

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.458

High

343359

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

343360

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.458

High

343361

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

343363

HIBCH
Small ribosomal subunit protein mS47

1

0

High-throughput

0.458

High

343366

DHOM
Homoserine dehydrogenase

1

0

High-throughput

0.458

High

343367

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

343369

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.458

High

343370

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

343373

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

343375

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

343377

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.458

High

343379

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

343380

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.458

High

343383

GID4
Vacuolar import and degradation protein 24

1

0

High-throughput

0.458

High

343384

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

343385

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

High-throughput

0.458

High

343386

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

0

High-throughput

0.458

High

343387

DNPEP
Aspartyl aminopeptidase 4

1

0

High-throughput

0.458

High

343388

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

343390

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

343391

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

343397

TM108
Protein TMA108

1

0

High-throughput

0.458

High

343400

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.458

High

343401

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.458

High

343403

DUG1
Cys-Gly metallodipeptidase DUG1

1

0

High-throughput

0.458

High

343406

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.458

High

343407

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.458

High

343408

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

343409

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.458

High

343410

SAP4
SIT4-associating protein SAP4

1

0

High-throughput

0.458

High

343413

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

343414

SHY1
Cytochrome oxidase assembly protein SHY1

1

0

Small-scale

0.458

High

343418

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

343419

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.458

High

343423

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

343427

OYE2
NADPH dehydrogenase 2

1

0

High-throughput

0.458

High

343433

VPS13
Intermembrane lipid transfer protein VPS13

1

0

High-throughput

0.458

High

343435

ZEO1
Protein ZEO1

1

0

High-throughput

0.458

High

343436

SGO1
Shugoshin

1

0

High-throughput

0.458

High

343437

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

343439

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

343443

HSP42
Heat shock protein 42

1

0

High-throughput

0.458

High

343341

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

343394

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

343337

YK104
Putative uncharacterized protein YKR104W

1

1

High-throughput

0.439

High

343364

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

343365

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

343420

ACT
Actin

1

1

Small-scale

0.437

High

343442

SMT3
Ubiquitin-like protein SMT3

1

1

High-throughput

0.437

High

343441

MAM3
Protein MAM3

1

0

High-throughput

0.426

High

343344

BPT1
Bile pigment transporter 1

1

0

High-throughput

0.282

High

343376

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.282

High

343434

YO075
Uncharacterized ABC transporter ATP-binding protein/permease YOL075C

1

0

High-throughput

0.282

High

343424

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.251

Low

343350

TPM1
Tropomyosin-1

1

0

Small-scale

0.249

Low

343362

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

343372

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

343374

IXR1
Intrastrand cross-link recognition protein

1

0

Small-scale

0.249

Low

343382

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

343399

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.249

Low

343405

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

343412

YGL7
Uncharacterized protein YGL117W

1

0

High-throughput

0.249

Low

343429

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.249

Low

343431

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

343432

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

343438

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

343440

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

343378

YET1
Endoplasmic reticulum transmembrane protein 1

1

0

High-throughput

0.232

Low

343389

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low

343396

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.232

Low

343398

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.232

Low

343404

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024