Protein: PLEK
Pleckstrin (Platelet 47 kDa protein) (p47)

Gene: PLEK
Organism: Homo sapiens
Interactions: 19
UniProt ID: P08567

Gene Ontology (top 5):
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0002576 - platelet degranulation
GO:0005080 - protein kinase C binding
GO:0005576 - extracellular region
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

471466

ARHG1
Rho guanine nucleotide exchange factor 1

1

10

High-throughput

0.665

High

471462

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.647

High

471461

A16L1
Autophagy-related protein 16-1

1

14

High-throughput

0.618

High

471460

I5P1
Inositol polyphosphate-5-phosphatase A

1

8

Small-scale

0.579

High

471463

WDR75
WD repeat-containing protein 75

2

7

High-throughput

0.558

High

346728

CAVN2
Caveolae-associated protein 2

1

1

Small-scale

0.536

High

471454

ACTN1
Alpha-actinin-1

1

7

Small-scale

0.484

High

471457

MOES
Moesin

1

17

Small-scale

0.484

High

471458

RADI
Radixin

1

16

Small-scale

0.484

High

471459

DHB4
Peroxisomal multifunctional enzyme type 2

1

2

Small-scale

0.484

High

471464

NHLC2
NHL repeat-containing protein 2

1

2

High-throughput

0.479

High

471465

LNX1
E3 ubiquitin-protein ligase LNX

1

18

Small-scale

0.479

High

390354

PLF4
Platelet factor 4

1

0

Small-scale

0.464

High

464402

TSP1
Thrombospondin-1

1

0

Small-scale

0.464

High

391118

HEMO
Hemopexin

1

0

High-throughput

0.458

High

471455

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.458

High

471456

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.458

High

361686

F13A
Coagulation factor XIII A chain

1

2

Small-scale

0.445

High

471467

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025