Protein: WDR75
WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog)

Gene: WDR75
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q8IWA0

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0032040 - small-subunit processome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1309697

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

5

18

Small-scale

0.709

High

643922

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

11

High-throughput

0.667

High

1309721

UTP16
U3 small nucleolar RNA-associated protein NOL7

3

0

High-throughput

0.634

High

749787

CADH5
Cadherin-5

2

3

High-throughput

0.628

High

1119063

C1D
Nuclear nucleic acid-binding protein C1D

2

2

High-throughput

0.628

High

1141393

WDR43
WD repeat-containing protein 43

2

20

High-throughput

0.628

High

1309687

WDFY3
WD repeat and FYVE domain-containing protein 3

2

16

High-throughput

0.628

High

1309706

RBM4
RNA-binding protein 4

2

12

High-throughput

0.628

High

1309714

EXOS5
Exosome complex component RRP46

2

19

High-throughput

0.628

High

1161527

IF16
Gamma-interferon-inducible protein 16

2

15

High-throughput

0.611

High

1309589

SPA12
Serpin A12

3

4

High-throughput

0.604

High

372504

MYC
Myc proto-oncogene protein

2

19

High-throughput

0.584

High

1087446

GRSF1
G-rich sequence factor 1

2

11

High-throughput

0.584

High

1309716

ANLN
Anillin

2

7

High-throughput

0.584

High

1038025

CACB1
Voltage-dependent L-type calcium channel subunit beta-1

2

1

High-throughput

0.574

High

1309711

ASB7
Ankyrin repeat and SOCS box protein 7

2

8

High-throughput

0.574

High

396461

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

471463

PLEK
Pleckstrin

2

7

High-throughput

0.558

High

228727

U3IP2
U3 small nucleolar RNA-interacting protein 2

1

19

High-throughput

0.536

High

301111

RL1D1
Ribosomal L1 domain-containing protein 1

1

11

High-throughput

0.536

High

833137

MNDA
Myeloid cell nuclear differentiation antigen

1

15

High-throughput

0.536

High

1016506

SRSF3
Serine/arginine-rich splicing factor 3

1

17

High-throughput

0.536

High

1118300

EXOS2
Exosome complex component RRP4

1

5

High-throughput

0.536

High

1144704

PWP2
Periodic tryptophan protein 2 homolog

1

19

High-throughput

0.536

High

1309691

UTP15
U3 small nucleolar RNA-associated protein 15 homolog

1

18

High-throughput

0.536

High

1309694

PSPC1
Paraspeckle component 1

1

17

High-throughput

0.536

High

1309704

MPH6
M-phase phosphoprotein 6

1

2

High-throughput

0.536

High

1309705

RBM4B
RNA-binding protein 4B

1

12

High-throughput

0.536

High

1309710

HEAT1
HEAT repeat-containing protein 1

1

6

High-throughput

0.536

High

1309713

NOL11
Nucleolar protein 11

1

3

High-throughput

0.536

High

1309715

EXOS3
Exosome complex component RRP40

1

5

High-throughput

0.536

High

1309720

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.513

High

1309722

FAN1
Fanconi-associated nuclease 1

1

0

High-throughput

0.513

High

269459

KI21B
Kinesin-like protein KIF21B

1

2

High-throughput

0.489

High

718424

CD6
T-cell differentiation antigen CD6

1

2

High-throughput

0.489

High

909081

NEK4
Serine/threonine-protein kinase Nek4

1

5

High-throughput

0.489

High

961190

FGF12
Fibroblast growth factor 12

1

1

High-throughput

0.489

High

1036666

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

1

High-throughput

0.489

High

1238999

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.489

High

1309698

ARRD3
Arrestin domain-containing protein 3

1

4

High-throughput

0.489

High

129238

MEN1
Menin

1

5

High-throughput

0.479

High

190985

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

223167

PRC1
Protein regulator of cytokinesis 1

1

9

High-throughput

0.479

High

247991

NUPR1
Nuclear protein 1

1

5

High-throughput

0.479

High

298409

DNJC8
DnaJ homolog subfamily C member 8

1

8

High-throughput

0.479

High

315756

RECQ4
ATP-dependent DNA helicase Q4

1

17

High-throughput

0.479

High

331122

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

346037

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

14

High-throughput

0.479

High

404196

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

414159

P53
Cellular tumor antigen p53

1

7

High-throughput

0.479

High

447196

NPM
Nucleophosmin

1

7

High-throughput

0.479

High

589096

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

695880

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

714251

PML
Protein PML

1

14

High-throughput

0.479

High

731440

STIP1
Stress-induced-phosphoprotein 1

1

13

High-throughput

0.479

High

766677

PHB1
Prohibitin 1

1

5

High-throughput

0.479

High

768592

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

879252

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

883275

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

7

High-throughput

0.479

High

937811

FOXA1
Hepatocyte nuclear factor 3-alpha

1

15

High-throughput

0.479

High

965075

WDR5
WD repeat-containing protein 5

1

16

High-throughput

0.479

High

979941

H4
Histone H4

1

10

High-throughput

0.479

High

1007729

RAE1L
mRNA export factor RAE1

1

18

High-throughput

0.479

High

1032194

EXOSX
Exosome complex component 10

1

8

High-throughput

0.479

High

1035757

KIF23
Kinesin-like protein KIF23

1

14

High-throughput

0.479

High

1045481

TF65
Transcription factor p65

1

2

High-throughput

0.479

High

1107002

BIRC3
Baculoviral IAP repeat-containing protein 3

1

9

High-throughput

0.479

High

1107890

SQSTM
Sequestosome-1

1

4

High-throughput

0.479

High

1113622

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1114926

CUL4A
Cullin-4A

1

20

High-throughput

0.479

High

1309690

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.479

High

1309692

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1309695

DNJC9
DnaJ homolog subfamily C member 9

1

15

High-throughput

0.479

High

1309696

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1309699

CHCH1
Small ribosomal subunit protein mS37

1

3

High-throughput

0.479

High

1309700

DCPS
m7GpppX diphosphatase

1

3

High-throughput

0.479

High

1309708

XRN2
5'-3' exoribonuclease 2

1

4

High-throughput

0.479

High

1309712

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

1309717

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

1309718

TLS1
Splicing factor C9orf78

1

5

High-throughput

0.479

High

1309719

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

11

High-throughput

0.479

High

1309689

MCPH1
Microcephalin

1

0

Small-scale

0.460

High

321850

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

0

High-throughput

0.458

High

374738

RASH
GTPase HRas

1

4

High-throughput

0.445

High

1006524

SRPK2
SRSF protein kinase 2

1

16

High-throughput

0.445

High

1130328

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

7

High-throughput

0.445

High

1309693

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

11

High-throughput

0.445

High

1309701

AURKB
Aurora kinase B

1

6

High-throughput

0.445

High

157585

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.437

High

272303

OBSL1
Obscurin-like protein 1

1

7

High-throughput

0.437

High

302886

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

20

High-throughput

0.437

High

1134977

CUL7
Cullin-7

1

7

High-throughput

0.437

High

1140519

KIF14
Kinesin-like protein KIF14

1

11

High-throughput

0.437

High

1246870

RICTR
Rapamycin-insensitive companion of mTOR

1

5

High-throughput

0.437

High

1254527

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.437

High

1276452

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.437

High

1309703

CI072
Guanine nucleotide exchange factor C9orf72

1

3

High-throughput

0.437

High

1309707

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

3

High-throughput

0.437

High

1309709

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1244318

PSRC1
Proline/serine-rich coiled-coil protein 1

1

0

High-throughput

0.426

High

1309431

APLF
Aprataxin and PNK-like factor

1

0

High-throughput

0.426

High

1309688

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.426

High

1309702

C170L
Cep170-like protein

1

1

High-throughput

0.407

High

292680

RENR
Renin receptor

1

0

High-throughput

0.279

Low

1178236

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

664884

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.232

Low

1010942

BAT1
b(0,+)-type amino acid transporter 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025