Protein: DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (ATP-dependent RNA helicase #3) (DEAH-box protein 16)

Gene: DHX16
Organism: Homo sapiens
Interactions: 142
UniProt ID: O60231

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0004386 - helicase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

224823

GPKOW
G-patch domain and KOW motifs-containing protein

4

2

Small-scale

0.919

High

224820

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

15

High-throughput

0.740

High

224847

SYF1
Pre-mRNA-splicing factor SYF1

1

15

High-throughput

0.740

High

224740

RIGI
Antiviral innate immune response receptor RIG-I

1

13

Small-scale

0.724

High

224809

CD20B
Cell division cycle protein 20 homolog B

1

8

High-throughput

0.691

High

224849

ANLN
Anillin

3

3

High-throughput

0.656

High

224754

TOP2A
DNA topoisomerase 2-alpha

1

0

High-throughput

0.631

High

224834

SETB2
Histone-lysine N-methyltransferase SETDB2

2

3

High-throughput

0.628

High

224856

TFP11
Tuftelin-interacting protein 11

1

8

High-throughput

0.621

High

224765

RECQ1
ATP-dependent DNA helicase Q1

1

12

High-throughput

0.618

High

224790

DHX8
ATP-dependent RNA helicase DHX8

1

15

High-throughput

0.618

High

224807

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.618

High

224811

DHX40
Probable ATP-dependent RNA helicase DHX40

1

14

High-throughput

0.618

High

224839

DDX23
Probable ATP-dependent RNA helicase DDX23

1

9

High-throughput

0.618

High

224842

TRIM6
Tripartite motif-containing protein 6

1

1

Small-scale

0.618

High

224764

COIL
Coilin

2

3

High-throughput

0.614

High

224737

CDKL5
Cyclin-dependent kinase-like 5

2

5

High-throughput

0.611

High

224818

SERB1
SERPINE1 mRNA-binding protein 1

2

3

High-throughput

0.611

High

224817

TTC29
Tetratricopeptide repeat protein 29

2

0

High-throughput

0.585

High

224734

BRD4
Bromodomain-containing protein 4

2

10

High-throughput

0.584

High

224786

SF3B2
Splicing factor 3B subunit 2

1

2

High-throughput

0.573

High

224776

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.569

High

224752

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

Small-scale

0.561

High

224733

ANM3
Protein arginine N-methyltransferase 3

1

3

High-throughput

0.536

High

224750

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.536

High

224753

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

224760

FOXN2
Forkhead box protein N2

1

4

High-throughput

0.536

High

224761

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.536

High

224769

JAK3
Tyrosine-protein kinase JAK3

1

4

High-throughput

0.536

High

224770

FOXL2
Forkhead box protein L2

1

3

High-throughput

0.536

High

224773

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.536

High

224774

SUMO1
Small ubiquitin-related modifier 1

1

2

High-throughput

0.536

High

224777

SERF2
Small EDRK-rich factor 2

1

1

High-throughput

0.536

High

224781

KPCD
Protein kinase C delta type

1

2

High-throughput

0.536

High

224784

SRSF6
Serine/arginine-rich splicing factor 6

1

8

High-throughput

0.536

High

224788

NOG2
Nucleolar GTP-binding protein 2

1

4

High-throughput

0.536

High

224792

RNPS1
RNA-binding protein with serine-rich domain 1

1

11

High-throughput

0.536

High

224793

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

6

High-throughput

0.536

High

224798

LBH
Protein LBH

1

1

High-throughput

0.536

High

224815

TXLNB
Beta-taxilin

1

5

High-throughput

0.536

High

224822

EZH1
Histone-lysine N-methyltransferase EZH1

1

5

High-throughput

0.536

High

224832

BIRC8
Baculoviral IAP repeat-containing protein 8

1

4

High-throughput

0.536

High

224833

NUDC1
NudC domain-containing protein 1

1

5

High-throughput

0.536

High

224843

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

5

High-throughput

0.536

High

204253

MS18B
Protein Mis18-beta

1

0

High-throughput

0.513

High

224744

FRIH
Ferritin heavy chain

1

0

High-throughput

0.513

High

224789

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.513

High

224797

AKIR2
Akirin-2

1

0

High-throughput

0.513

High

224801

ZFY27
Protrudin

1

0

High-throughput

0.513

High

224803

LEG9C
Galectin-9C

1

0

High-throughput

0.513

High

224805

CPLX2
Complexin-2

1

0

High-throughput

0.513

High

224830

AJUBA
LIM domain-containing protein ajuba

1

0

High-throughput

0.513

High

224838

TCAL7
Transcription elongation factor A protein-like 7

1

0

High-throughput

0.513

High

224846

CSR2B
Cysteine-rich protein 2-binding protein

1

0

High-throughput

0.513

High

224859

FBX5
F-box only protein 5

1

0

High-throughput

0.513

High

224862

POLH
DNA polymerase eta

1

0

High-throughput

0.513

High

224865

MB212
Protein mab-21-like 2

1

0

High-throughput

0.513

High

224826

ESS2
Splicing factor ESS-2 homolog

1

2

High-throughput

0.508

High

224763

DEK
Protein DEK

1

0

High-throughput

0.493

High

224806

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

1

High-throughput

0.489

High

224855

PEN2
Gamma-secretase subunit PEN-2

1

1

High-throughput

0.489

High

224748

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

133249

NOP56
Nucleolar protein 56

1

4

High-throughput

0.479

High

148179

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

162239

XPO1
Exportin-1

1

4

High-throughput

0.479

High

179477

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

2

High-throughput

0.479

High

224731

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

224735

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.479

High

224736

TAD2A
Transcriptional adapter 2-alpha

1

3

High-throughput

0.479

High

224739

KI20A
Kinesin-like protein KIF20A

1

7

High-throughput

0.479

High

224741

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

224742

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

224743

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

High-throughput

0.479

High

224745

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

224746

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.479

High

224747

P53
Cellular tumor antigen p53

1

3

High-throughput

0.479

High

224751

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

224755

XRCC6
X-ray repair cross-complementing protein 6

1

2

High-throughput

0.479

High

224756

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

224758

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

224762

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

224767

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

224771

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

224772

H2B1C
Histone H2B type 1-C/E/F/G/I

1

7

High-throughput

0.479

High

224775

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.479

High

224778

H33
Histone H3.3

1

4

High-throughput

0.479

High

224779

VIGLN
Vigilin

1

3

High-throughput

0.479

High

224780

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

224782

EP300
Histone acetyltransferase p300

1

10

High-throughput

0.479

High

224783

CBX3
Chromobox protein homolog 3

1

2

High-throughput

0.479

High

224785

TIF1B
Transcription intermediary factor 1-beta

1

9

High-throughput

0.479

High

224787

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

224791

CUL7
Cullin-7

1

2

High-throughput

0.479

High

224794

IF16
Gamma-interferon-inducible protein 16

1

6

High-throughput

0.479

High

224799

HABP4
Intracellular hyaluronan-binding protein 4

1

3

High-throughput

0.479

High

224804

IFIX
Pyrin and HIN domain-containing protein 1

1

6

High-throughput

0.479

High

224808

MAVS
Mitochondrial antiviral-signaling protein

1

2

Small-scale

0.479

High

224812

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.479

High

224813

SRRM1
Serine/arginine repetitive matrix protein 1

1

3

High-throughput

0.479

High

224824

FBXW7
F-box/WD repeat-containing protein 7

1

4

High-throughput

0.479

High

224827

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

8

High-throughput

0.479

High

224829

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

224835

CDC5L
Cell division cycle 5-like protein

1

11

High-throughput

0.479

High

224840

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

4

High-throughput

0.479

High

224845

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

224848

BRD7
Bromodomain-containing protein 7

1

12

High-throughput

0.479

High

224850

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

224852

ARGL1
Arginine and glutamate-rich protein 1

1

3

High-throughput

0.479

High

224853

AATF
Protein AATF

1

1

High-throughput

0.479

High

224854

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

224857

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

224860

NUP50
Nuclear pore complex protein Nup50

1

3

High-throughput

0.479

High

224861

SRRM2
Serine/arginine repetitive matrix protein 2

1

4

High-throughput

0.479

High

224864

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

224831

MEG10
Multiple epidermal growth factor-like domains protein 10

1

2

Small-scale

0.464

High

224810

HOMEZ
Homeobox and leucine zipper protein Homez

1

0

High-throughput

0.460

High

224821

APBP2
Amyloid protein-binding protein 2

1

0

High-throughput

0.460

High

224828

MYO19
Unconventional myosin-XIX

1

0

High-throughput

0.460

High

224759

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

224836

CTIP
DNA endonuclease RBBP8

1

0

Small-scale

0.458

High

224851

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

224858

TNIK
TRAF2 and NCK-interacting protein kinase

1

1

High-throughput

0.457

High

224749

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

224796

NCBP3
Nuclear cap-binding protein subunit 3

1

2

High-throughput

0.445

High

224800

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

224819

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

2

High-throughput

0.445

High

224738

RHBT1
Rho-related BTB domain-containing protein 1

1

1

High-throughput

0.437

High

224837

LZTS2
Leucine zipper putative tumor suppressor 2

1

7

High-throughput

0.437

High

224844

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

6

High-throughput

0.437

High

224757

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.407

High

224766

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

224802

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

224814

CT197
Putative uncharacterized protein encoded by LINC02910

1

0

High-throughput

0.279

Low

224816

CB073
Uncharacterized protein C2orf73

1

0

High-throughput

0.279

Low

224825

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

224863

AP3M1
AP-3 complex subunit mu-1

1

0

High-throughput

0.279

Low

224866

FADS3
Fatty acid desaturase 3

1

0

High-throughput

0.279

Low

224867

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

224732

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

0

High-throughput

0.269

Low

224768

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

High-throughput

0.269

Low

224795

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

224841

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024