Protein: OSM1
Fumarate reductase 2 (FRDS2) (EC 1.3.1.6) (NADH-dependent fumarate reductase) (Osmotic sensitivity protein 1) (Soluble fumarate reductase, mitochondrial isozyme)

Gene: OSM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 34
UniProt ID: P21375

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum
GO:0010181 - FMN binding
GO:0016156 - fumarate reductase (NADH) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

638114

ERO1
Endoplasmic oxidoreductin-1

1

0

Small-scale

0.537

High

638098

ERV1
Mitochondrial FAD-linked sulfhydryl oxidase ERV1

1

0

Small-scale

0.480

High

638104

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

Small-scale

0.480

High

558581

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

578839

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

638101

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.479

High

638110

TOM22
Mitochondrial import receptor subunit TOM22

1

2

High-throughput

0.479

High

638111

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.479

High

638112

HST2
NAD-dependent protein deacetylase HST2

1

2

High-throughput

0.479

High

638113

CDC14
Tyrosine-protein phosphatase CDC14

1

3

High-throughput

0.479

High

365558

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

638097

BUD14
Bud site selection protein 14

1

0

High-throughput

0.458

High

638100

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.458

High

638115

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

638118

YM87
Uncharacterized membrane protein YMR253C

1

0

High-throughput

0.458

High

392223

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.445

High

481479

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

523050

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

525914

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

543806

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

638096

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

638099

HS104
Heat shock protein 104

1

5

High-throughput

0.445

High

638103

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

638105

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

638106

DJP1
DnaJ-like protein 1

1

3

High-throughput

0.445

High

638108

TCPQ
T-complex protein 1 subunit theta

1

2

High-throughput

0.445

High

638109

DPH4
Diphthamide biosynthesis protein 4

1

2

High-throughput

0.445

High

638119

RBX1
RING-box protein HRT1

1

0

High-throughput

0.438

High

638102

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

638107

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

638095

SIS1
Protein SIS1

1

2

High-throughput

0.407

High

638120

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.269

Low

638117

AIM32
Altered inheritance of mitochondria protein 32

1

0

Small-scale

0.261

Low

638116

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025