Protein: DOT5
Peroxiredoxin DOT5 (Prx) (EC 1.11.1.24) (Disrupter of telomere silencing protein 5) (Nuclear thiol peroxidase) (nTPx) (Thioredoxin peroxidase) (Thioredoxin-dependent peroxiredoxin DOT5)

Gene: DOT5
Organism: Saccharomyces cerevisiae S288C
Interactions: 23
UniProt ID: P40553

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008379 - thioredoxin peroxidase activity
GO:0034599 - cellular response to oxidative stress

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

704612

SBA1
Co-chaperone protein SBA1

2

0

Small-scale

0.583

High

602505

PHO85
Cyclin-dependent protein kinase PHO85

1

11

High-throughput

0.501

High

656498

KC11
Casein kinase I homolog 1

1

3

High-throughput

0.501

High

692373

KCC1
Calcium/calmodulin-dependent protein kinase I

1

2

High-throughput

0.501

High

808637

AURK
Aurora kinase

1

3

High-throughput

0.501

High

826307

GIN4
Serine/threonine-protein kinase GIN4

1

4

High-throughput

0.501

High

826308

CMR1
DNA damage-binding protein CMR1

1

5

High-throughput

0.481

High

594412

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

679777

CDC48
Cell division control protein 48

1

7

High-throughput

0.479

High

707327

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

826303

HFM1
ATP-dependent DNA helicase MER3

1

1

Small-scale

0.479

High

365787

KTHY
Thymidylate kinase

1

0

High-throughput

0.458

High

808835

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

826305

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.458

High

826306

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

524201

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

526901

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

545177

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

741742

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

818966

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

513510

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.437

High

812381

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

826304

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025