Protein: STH1
Nuclear protein STH1/NPS1 (EC 3.6.4.12) (ATP-dependent helicase STH1) (Chromatin structure-remodeling complex protein STH1) (SNF2 homolog)

Gene: STH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 155
UniProt ID: P32597

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

696260

RSC2
Chromatin structure-remodeling complex subunit RSC2

23

19

Small-scale

0.989

High

696264

RSC58
Chromatin structure-remodeling complex protein RSC58

11

2

Small-scale

0.977

High

696241

RSC4
Chromatin structure-remodeling complex subunit RSC4

12

20

Small-scale

0.976

High

696256

ARP9
Actin-like protein ARP9

10

20

Small-scale

0.975

High

696272

ARP7
Actin-related protein 7

11

20

Small-scale

0.974

High

696232

RSC1
Chromatin structure-remodeling complex subunit RSC1

10

19

Small-scale

0.970

High

696239

H3
Histone H3

7

20

Small-scale

0.961

High

356344

H4
Histone H4

5

15

Small-scale

0.928

High

355406

H2B1
Histone H2B.1

3

20

Small-scale

0.871

High

392357

H2A2
Histone H2A.2

4

20

Small-scale

0.867

High

355832

H2B2
Histone H2B.2

3

20

High-throughput

0.830

High

687673

BTAF1
TATA-binding protein-associated factor MOT1

2

18

Small-scale

0.789

High

696223

RSC8
Chromatin structure-remodeling complex protein RSC8

13

20

Small-scale

0.761

High

696233

RT102
Regulator of Ty1 transposition protein 102

11

2

Small-scale

0.757

High

696261

RSC3
Chromatin structure-remodeling complex protein RSC3

11

2

Small-scale

0.756

High

635493

RSC6
Chromatin structure-remodeling complex protein RSC6

11

20

Small-scale

0.756

High

696185

RSC7
Chromatin structure-remodeling complex subunit RSC7

9

3

Small-scale

0.754

High

696258

SFH1
Chromatin structure-remodeling complex subunit SFH1

9

11

Small-scale

0.752

High

696276

HTL1
High temperature lethal protein 1

7

2

Small-scale

0.746

High

696244

RSC9
Chromatin structure-remodeling complex subunit RSC9

8

2

Small-scale

0.745

High

696197

CENPA
Histone H3-like centromeric protein CSE4

2

20

Small-scale

0.743

High

696193

TAF14
Transcription initiation factor TFIID subunit 14

6

3

Small-scale

0.740

High

696275

H2AZ
Histone H2A.Z

2

20

High-throughput

0.737

High

696245

GCN5
Histone acetyltransferase GCN5

2

20

High-throughput

0.712

High

696207

RSC30
Chromatin structure-remodeling complex protein RSC30

5

2

Small-scale

0.711

High

603293

SNF2
Transcription regulatory protein SNF2

1

16

High-throughput

0.691

High

696202

LDB7
Chromatin structure-remodeling complex protein RSC14

4

2

Small-scale

0.689

High

696270

SCC1
Sister chromatid cohesion protein 1

4

7

Small-scale

0.686

High

696215

ATAD2
ATPase histone chaperone YTA7

4

5

Small-scale

0.672

High

696212

SCC4
MAU2 chromatid cohesion factor homolog

3

4

Small-scale

0.664

High

696249

SCC2
Sister chromatid cohesion protein 2

3

3

Small-scale

0.664

High

375326

RPB1
DNA-directed RNA polymerase II subunit RPB1

3

9

Small-scale

0.640

High

490681

HSP71
Heat shock protein SSA1

3

20

High-throughput

0.633

High

557954

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

4

High-throughput

0.618

High

606593

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.618

High

696184

CHD1
Chromo domain-containing protein 1

1

16

High-throughput

0.618

High

696196

BDF1
Bromodomain-containing factor 1

1

20

High-throughput

0.618

High

696200

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

17

High-throughput

0.618

High

696248

RUVB1
RuvB-like protein 1

1

8

High-throughput

0.618

High

696262

BDF2
Bromodomain-containing factor 2

1

20

High-throughput

0.618

High

696273

RUVB2
RuvB-like protein 2

1

8

High-throughput

0.618

High

696259

YL455
PWWP domain-containing protein YLR455W

2

10

Small-scale

0.611

High

510662

SSB1
Ribosome-associated molecular chaperone SSB1

2

20

High-throughput

0.601

High

514161

NHP6A
Non-histone chromosomal protein 6A

2

20

Small-scale

0.601

High

514244

NHP6B
Non-histone chromosomal protein 6B

2

20

High-throughput

0.588

High

696229

RFX1
RFX-like DNA-binding protein RFX1

2

7

High-throughput

0.588

High

375591

RPC1
DNA-directed RNA polymerase III subunit RPC1

2

9

Small-scale

0.584

High

689851

ASF1
Histone chaperone ASF1

1

10

High-throughput

0.575

High

696254

RCO1
Transcriptional regulatory protein RCO1

1

20

High-throughput

0.575

High

696257

SWR1
Helicase SWR1

1

15

High-throughput

0.575

High

696192

SAS3
Histone acetyltransferase SAS3

2

9

High-throughput

0.571

High

696194

SPT10
Protein SPT10

2

4

High-throughput

0.571

High

696237

APJ1
J domain-containing protein APJ1

2

9

High-throughput

0.571

High

696243

HOS3
Histone deacetylase HOS3

2

20

High-throughput

0.571

High

696253

POB3
FACT complex subunit POB3

2

8

High-throughput

0.571

High

599434

VPS1
Vacuolar protein sorting-associated protein 1

1

4

High-throughput

0.536

High

696271

HSP42
Heat shock protein 42

1

3

High-throughput

0.536

High

691005

HOG1
Mitogen-activated protein kinase HOG1

1

1

Small-scale

0.515

High

696203

TCM62
Mitochondrial chaperone TCM62

1

2

High-throughput

0.515

High

696221

RIM15
Serine/threonine-protein kinase RIM15

1

5

High-throughput

0.515

High

696201

NU170
Nucleoporin NUP170

1

0

Small-scale

0.513

High

696236

DMA2
E3 ubiquitin-protein ligase DMA2

1

0

High-throughput

0.513

High

368725

GCN4
General control transcription factor GCN4

1

1

Small-scale

0.479

High

406901

RS3
Small ribosomal subunit protein uS3

1

5

High-throughput

0.479

High

420101

TOP2
DNA topoisomerase 2

1

9

High-throughput

0.479

High

501341

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

9

Small-scale

0.479

High

526973

TBP
TATA-box-binding protein

1

3

High-throughput

0.479

High

534516

HAP4
Transcriptional activator HAP4

1

1

Small-scale

0.479

High

554600

HSP26
Heat shock protein 26

1

3

Small-scale

0.479

High

607235

RFA1
Replication factor A protein 1

1

9

Small-scale

0.479

High

661681

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

680549

HS104
Heat shock protein 104

1

4

High-throughput

0.479

High

688159

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

692720

SPT16
FACT complex subunit SPT16

1

5

High-throughput

0.479

High

696186

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

11

High-throughput

0.479

High

696187

SMC1
Structural maintenance of chromosomes protein 1

1

8

Small-scale

0.479

High

696195

SPT21
Protein SPT21

1

3

High-throughput

0.479

High

696199

GBLP
Small ribosomal subunit protein RACK1

1

16

High-throughput

0.479

High

696205

LEO1
RNA polymerase-associated protein LEO1

1

5

Small-scale

0.479

High

696216

MAM33
Mitochondrial acidic protein MAM33

1

1

High-throughput

0.479

High

696217

SCC3
Cohesin subunit SCC3

1

1

Small-scale

0.479

High

696219

DSN1
Kinetochore-associated protein DSN1

1

4

High-throughput

0.479

High

696226

SMC3
Structural maintenance of chromosomes protein 3

1

8

Small-scale

0.479

High

696230

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.479

High

696242

XRN2
5'-3' exoribonuclease 2

1

3

High-throughput

0.479

High

696250

IOC4
ISWI one complex protein 4

1

2

High-throughput

0.479

High

696252

DPB4
DNA polymerase epsilon subunit D

1

5

Small-scale

0.479

High

696265

MED7
Mediator of RNA polymerase II transcription subunit 7

1

1

Small-scale

0.479

High

696266

SGO1
Shugoshin

1

2

High-throughput

0.479

High

696267

ESA1
Histone acetyltransferase ESA1

1

9

Small-scale

0.479

High

696269

IOC2
ISWI one complex protein 2

1

2

High-throughput

0.479

High

690900

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

5

High-throughput

0.470

High

597107

IME1
Meiosis-inducing protein 1

1

0

Small-scale

0.458

High

689034

TFC1
Transcription factor tau 95 kDa subunit

1

0

High-throughput

0.458

High

696227

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

366003

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.445

High

419322

HAP2
Transcriptional activator HAP2

1

5

High-throughput

0.445

High

449972

HSP73
Heat shock protein SSA3

1

20

High-throughput

0.445

High

457006

SWI6
Regulatory protein SWI6

1

9

High-throughput

0.445

High

493493

HSP72
Heat shock protein SSA2

1

20

High-throughput

0.445

High

515047

MCM1
Pheromone receptor transcription factor

1

10

High-throughput

0.445

High

516287

RAP1
DNA-binding protein RAP1

1

2

High-throughput

0.445

High

535757

ABF1
ARS-binding factor 1

1

1

High-throughput

0.445

High

605219

AFT1
Iron-regulated transcriptional activator AFT1

1

2

High-throughput

0.445

High

609060

SIN3
Transcriptional regulatory protein SIN3

1

16

High-throughput

0.445

High

612215

HSP12
12 kDa heat shock protein

1

1

High-throughput

0.445

High

628850

SWI4
Regulatory protein SWI4

1

9

High-throughput

0.445

High

633057

MAS5
Mitochondrial protein import protein MAS5

1

9

High-throughput

0.445

High

691886

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

1

High-throughput

0.445

High

694335

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

695922

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.445

High

696189

IXR1
Intrastrand cross-link recognition protein

1

20

High-throughput

0.445

High

696191

MSN2
Zinc finger protein MSN2

1

13

High-throughput

0.445

High

696198

SET3
SET domain-containing protein 3

1

18

High-throughput

0.445

High

696208

SSZ1
Ribosome-associated complex subunit SSZ1

1

15

High-throughput

0.445

High

696209

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

20

High-throughput

0.445

High

696211

HSP7E
Heat shock protein SSC3, mitochondrial

1

16

High-throughput

0.445

High

696213

SSB2
Ribosome-associated molecular chaperone SSB2

1

20

High-throughput

0.445

High

696214

RT106
Histone chaperone RTT106

1

3

High-throughput

0.445

High

696220

AZF1
Transcription factor AZF1

1

3

High-throughput

0.445

High

696224

TAF1
Transcription initiation factor TFIID subunit 1

1

4

High-throughput

0.445

High

696238

MOT3
Transcriptional activator/repressor MOT3

1

1

High-throughput

0.445

High

696247

GIS1
Transcriptional activator/repressor GIS1

1

8

High-throughput

0.445

High

696263

BRE1
E3 ubiquitin-protein ligase BRE1

1

15

High-throughput

0.445

High

696274

RLF2
Chromatin assembly factor 1 subunit p90

1

13

High-throughput

0.445

High

357957

RS17A
Small ribosomal subunit protein eS17A

1

4

High-throughput

0.437

High

383028

RL25
Large ribosomal subunit protein uL23

1

4

High-throughput

0.437

High

407810

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.437

High

413393

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.437

High

425838

RS19A
Small ribosomal subunit protein eS19A

1

6

High-throughput

0.437

High

470943

RS22A
Small ribosomal subunit protein uS8A

1

4

High-throughput

0.437

High

472094

RL31A
Large ribosomal subunit protein eL31A

1

4

High-throughput

0.437

High

480559

RS8A
Small ribosomal subunit protein eS8A

1

4

High-throughput

0.437

High

482157

RS18A
Small ribosomal subunit protein uS13A

1

4

High-throughput

0.437

High

631754

RS2
Small ribosomal subunit protein uS5

1

5

High-throughput

0.437

High

696188

SMY2
Protein SMY2

1

2

High-throughput

0.437

High

696190

RS3A1
Small ribosomal subunit protein eS1A

1

5

High-throughput

0.437

High

696206

RS20
Small ribosomal subunit protein uS10

1

4

High-throughput

0.437

High

696228

RS12
Small ribosomal subunit protein eS12

1

4

High-throughput

0.437

High

696240

RS15
Small ribosomal subunit protein uS19

1

4

High-throughput

0.437

High

696268

RS10A
Small ribosomal subunit protein eS10A

1

4

High-throughput

0.437

High

696183

RTG1
Retrograde regulation protein 1

1

0

High-throughput

0.426

High

696210

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.426

High

696225

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

696231

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

696255

YM94
Uncharacterized protein YMR315W

1

0

High-throughput

0.426

High

367877

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.407

High

696218

DJP1
DnaJ-like protein 1

1

6

High-throughput

0.407

High

696234

JJJ1
J protein JJJ1

1

5

High-throughput

0.407

High

696251

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.407

High

696246

NUP53
Nucleoporin NUP53

1

0

Small-scale

0.279

Low

693771

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.269

Low

696222

BUD27
Bud site selection protein 27

1

0

Small-scale

0.249

Low

696204

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.232

Low

696235

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024