Protein: THG1
tRNA(His) guanylyltransferase (EC 2.7.7.79) (tRNA-histidine guanylyltransferase)

Gene: THG1
Organism: Saccharomyces cerevisiae S288C
Interactions: 83
UniProt ID: P53215

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006400 - tRNA modification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

918259

THG1
tRNA(His) guanylyltransferase

4

2

Small-scale

0.878

High

918267

IMA1
Importin subunit alpha

2

0

High-throughput

0.582

High

802841

YHR2
Uncharacterized trans-sulfuration enzyme YHR112C

2

0

High-throughput

0.565

High

745659

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.529

High

722117

XPO1
Exportin-1

1

0

High-throughput

0.513

High

918268

GDE1
Glycerophosphocholine phosphodiesterase GDE1

1

0

High-throughput

0.486

High

800738

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.480

High

393072

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

579783

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

741022

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

707722

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

805152

YHP7
Uncharacterized protein YHR097C

1

0

High-throughput

0.458

High

918274

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

892967

SART3
U4/U6 snRNA-associated-splicing factor PRP24

1

1

High-throughput

0.457

High

403589

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.438

High

416461

HXKA
Hexokinase-1

1

0

High-throughput

0.438

High

448592

RHO2
GTP-binding protein RHO2

1

0

High-throughput

0.438

High

548788

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.438

High

632099

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.438

High

632393

CG11
G1/S-specific cyclin CLN1

1

0

High-throughput

0.438

High

651967

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.438

High

739082

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

0

High-throughput

0.438

High

744209

RAD24
Checkpoint protein RAD24

1

0

High-throughput

0.438

High

778963

KDX1
Serine/threonine-protein kinase KDX1

1

0

High-throughput

0.438

High

798085

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.438

High

803993

RSC30
Chromatin structure-remodeling complex protein RSC30

1

0

High-throughput

0.438

High

805469

DMA1
E3 ubiquitin-protein ligase DMA1

1

0

High-throughput

0.438

High

806981

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.438

High

811652

CIN4
GTP-binding protein CIN4

1

0

High-throughput

0.438

High

818091

SLX8
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8

1

0

High-throughput

0.438

High

844366

TDA10
Probable ATP-dependent kinase TDA10

1

0

High-throughput

0.438

High

863604

GON7
EKC/KEOPS complex subunit GON7

1

0

High-throughput

0.438

High

865252

YJY5
Uncharacterized endoplasmic reticulum membrane protein YJR015W

1

0

High-throughput

0.438

High

917387

PCL10
PHO85 cyclin-10

1

0

High-throughput

0.438

High

918260

YN87
Uncharacterized protein YNR014W

1

0

High-throughput

0.438

High

918261

CAF40
Protein CAF40

1

0

High-throughput

0.438

High

918263

ADE
Adenine deaminase

1

0

High-throughput

0.438

High

918264

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.438

High

918265

YP068
Uncharacterized protein YPL068C

1

0

High-throughput

0.438

High

918269

ECM5
Protein ECM5

1

0

High-throughput

0.438

High

918272

SND1
SRP-independent targeting protein 1

1

0

High-throughput

0.438

High

918278

SCM3
Protein SCM3

1

0

High-throughput

0.438

High

918279

TRM10
tRNA

1

0

High-throughput

0.438

High

918282

YI31A
Transposon Ty3-I Gag polyprotein

1

0

High-throughput

0.438

High

545670

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

738676

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.282

High

780585

CUE2
Endonuclease CUE2

1

0

High-throughput

0.265

Low

150050

YP044
Putative uncharacterized protein YPL044C

1

0

High-throughput

0.238

Low

150230

YL463
Putative uncharacterized protein YLR463C

1

0

High-throughput

0.238

Low

150239

YL169
Putative uncharacterized protein YLR169W

1

0

High-throughput

0.238

Low

150326

YP130
Putative uncharacterized protein YPR130C

1

0

High-throughput

0.238

Low

367079

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.238

Low

410243

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.238

Low

416310

SYWM
Tryptophan--tRNA ligase, mitochondrial

1

0

High-throughput

0.238

Low

632578

DBP3
ATP-dependent RNA helicase DBP3

1

0

High-throughput

0.238

Low

663698

RL24B
Large ribosomal subunit protein eL24B

1

0

High-throughput

0.238

Low

677722

VAC17
vacuole-related protein 17

1

0

High-throughput

0.238

Low

697333

COQ8
Atypical kinase COQ8, mitochondrial

1

0

High-throughput

0.238

Low

746648

DRS1
ATP-dependent RNA helicase DRS1

1

0

High-throughput

0.238

Low

797485

TOS1
Probable circularly permuted 1,3-beta-glucanase TOS1

1

0

High-throughput

0.238

Low

797573

YB28
Putative uncharacterized protein YBR178W

1

0

High-throughput

0.238

Low

800642

YGP1
Protein YGP1

1

0

High-throughput

0.238

Low

805166

SFB3
SED5-binding protein 3

1

0

High-throughput

0.238

Low

808689

SUR2
Sphingolipid C4-hydroxylase SUR2

1

0

High-throughput

0.238

Low

810858

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.238

Low

817365

RSM18
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.238

Low

818399

TAPT1
Endoplasmic reticulum membrane protein 65

1

0

High-throughput

0.238

Low

823248

SEC9
Protein transport protein SEC9

1

0

High-throughput

0.238

Low

827063

GPX3
Glutathione peroxidase-like peroxiredoxin HYR1

1

0

High-throughput

0.238

Low

843227

ZIM17
Mitochondrial protein import protein ZIM17

1

0

High-throughput

0.238

Low

849573

YFG7
Uncharacterized membrane protein YFL067W

1

0

High-throughput

0.238

Low

873843

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.238

Low

918262

YNR9
Putative uncharacterized protein YNL179C

1

0

High-throughput

0.238

Low

918266

NCE1
Non-classical export protein 1

1

0

High-throughput

0.238

Low

918270

YM46
Uncharacterized protein YMR181C

1

0

High-throughput

0.238

Low

918271

TR130
Trafficking protein particle complex II-specific subunit 130

1

0

High-throughput

0.238

Low

918273

YMI3
Putative uncharacterized protein YML083C

1

0

High-throughput

0.238

Low

918275

AAD4
Probable aryl-alcohol dehydrogenase AAD4

1

0

High-throughput

0.238

Low

918276

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

0

High-throughput

0.238

Low

918277

PGC1
Phosphatidylglycerol phospholipase C

1

0

High-throughput

0.238

Low

918280

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.238

Low

918281

RS21B
Small ribosomal subunit protein eS21B

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025