Protein: RL6
Large ribosomal subunit protein uL6 (50S ribosomal protein L6)

Gene: RL6, rplF
Organism: Escherichia coli K-12
Interactions: 92
UniProt ID: P0AG55

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

491437

IF2
Translation initiation factor IF-2

1

2

High-throughput

0.691

High

491745

LPXA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase

2

1

High-throughput

0.612

High

368958

SYGA
Glycine--tRNA ligase alpha subunit

2

1

High-throughput

0.588

High

497096

DEAD
ATP-dependent RNA helicase DeaD

2

2

High-throughput

0.588

High

501292

RLUB
Ribosomal large subunit pseudouridine synthase B

2

1

High-throughput

0.588

High

501298

RL4
Large ribosomal subunit protein uL4

2

1

High-throughput

0.588

High

501299

RLMB
23S rRNA

2

1

High-throughput

0.588

High

494951

TIG
Trigger factor

2

0

Small-scale

0.576

High

499923

RL23
Large ribosomal subunit protein uL23

2

0

High-throughput

0.576

High

494795

SSRP
SsrA-binding protein

2

0

High-throughput

0.563

High

497987

YBCJ
Putative RNA-binding protein YbcJ

2

0

High-throughput

0.563

High

501278

RNR
Ribonuclease R

2

0

High-throughput

0.563

High

491323

HSCA
Chaperone protein HscA

1

3

High-throughput

0.536

High

492871

RL27
Large ribosomal subunit protein bL27

1

1

High-throughput

0.536

High

496953

PTA
Phosphate acetyltransferase

1

1

High-throughput

0.536

High

501294

HEMW
Heme chaperone HemW

1

1

High-throughput

0.536

High

501297

RL2
Large ribosomal subunit protein uL2

1

3

High-throughput

0.536

High

408527

3MG2
DNA-3-methyladenine glycosylase 2

1

0

High-throughput

0.513

High

445445

MUTH
DNA mismatch repair protein MutH

1

0

High-throughput

0.513

High

469924

RECB
RecBCD enzyme subunit RecB

1

0

High-throughput

0.513

High

478373

EX3
Exodeoxyribonuclease III

1

0

High-throughput

0.513

High

491766

MINE
Cell division topological specificity factor

1

0

High-throughput

0.513

High

494622

RPOA
DNA-directed RNA polymerase subunit alpha

1

0

High-throughput

0.513

High

495400

YIHI
Der GTPase-activating protein YihI

1

0

High-throughput

0.513

High

496540

GLPX
Fructose-1,6-bisphosphatase 1 class 2

1

0

High-throughput

0.513

High

496785

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.513

High

498091

YCED
Large ribosomal RNA subunit accumulation protein YceD

1

0

High-throughput

0.513

High

499498

YEBG
Uncharacterized protein YebG

1

0

High-throughput

0.513

High

499699

ENTB
Enterobactin synthase component B

1

0

High-throughput

0.513

High

500370

FRE
NAD(P)H-flavin reductase

1

0

High-throughput

0.513

High

500702

NUSA
Transcription termination/antitermination protein NusA

1

0

High-throughput

0.513

High

501034

SSPB
Stringent starvation protein B

1

0

High-throughput

0.513

High

501277

FDHE
Protein FdhE

1

0

High-throughput

0.513

High

501280

PHOP
Transcriptional regulatory protein PhoP

1

0

High-throughput

0.513

High

501282

ACPS
Holo-[acyl-carrier-protein] synthase

1

0

High-throughput

0.513

High

501284

MOAD
Molybdopterin synthase sulfur carrier subunit

1

0

High-throughput

0.513

High

501285

YIIS
UPF0381 protein YiiS

1

0

High-throughput

0.513

High

501286

PSUG
Pseudouridine-5'-phosphate glycosidase

1

0

High-throughput

0.513

High

501290

NUDK
GDP-mannose pyrophosphatase

1

0

High-throughput

0.513

High

501301

YFCD
Uncharacterized Nudix hydrolase YfcD

1

0

High-throughput

0.513

High

501303

PTFAH
Multiphosphoryl transfer protein

1

0

High-throughput

0.513

High

498235

ATPB
ATP synthase subunit beta

1

1

High-throughput

0.489

High

501315

HSCC
Chaperone protein HscC

1

5

High-throughput

0.489

High

491100

DNAK
Chaperone protein DnaK

1

1

High-throughput

0.484

High

497624

RLUC
Ribosomal large subunit pseudouridine synthase C

1

1

High-throughput

0.484

High

501275

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

1

High-throughput

0.484

High

501288

CBPA
Curved DNA-binding protein

1

1

High-throughput

0.484

High

421119

PNP
Polyribonucleotide nucleotidyltransferase

1

0

High-throughput

0.464

High

490673

FABZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

1

0

High-throughput

0.464

High

491547

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

0

High-throughput

0.464

High

491941

RPPH
RNA pyrophosphohydrolase

1

0

High-throughput

0.464

High

496724

PHOL
PhoH-like protein

1

0

High-throughput

0.464

High

501289

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.464

High

491862

NAGB
Glucosamine-6-phosphate deaminase

1

0

High-throughput

0.458

High

495572

TMAR
Pole-localizer protein TmaR

1

0

High-throughput

0.458

High

495974

YFBU
UPF0304 protein YfbU

1

0

High-throughput

0.458

High

501276

YHBY
RNA-binding protein YhbY

1

0

High-throughput

0.458

High

501283

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

0

High-throughput

0.458

High

501304

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

492038

PLSB
Glycerol-3-phosphate acyltransferase

2

0

High-throughput

0.319

High

501305

YBJX
Uncharacterized protein YbjX

2

0

High-throughput

0.307

High

367445

TRPE
Anthranilate synthase component 1

1

0

High-throughput

0.279

Low

480949

GLPQ
Glycerophosphodiester phosphodiesterase, periplasmic

1

0

High-throughput

0.279

Low

495876

RBN
Ribonuclease BN

1

0

High-throughput

0.279

Low

497686

YOBA
Protein YobA

1

0

High-throughput

0.279

Low

498113

YCGL
Protein YcgL

1

0

High-throughput

0.279

Low

499473

FUMD
Fumarase D

1

0

High-throughput

0.279

Low

499527

YECA
Uncharacterized protein YecA

1

0

High-throughput

0.279

Low

500837

OSMY
Osmotically-inducible protein Y

1

0

High-throughput

0.279

Low

501279

FECI
Ferric citrate uptake sigma factor FecI

1

0

High-throughput

0.279

Low

501281

PRIC
Replication restart protein PriC

1

0

High-throughput

0.279

Low

501287

BGLX
Periplasmic beta-glucosidase

1

0

High-throughput

0.279

Low

501293

YFAL
Probable autotransporter YfaL [Cleaved into: Probable secreted autotransporter protein YfaL; Probable autotransporter YfaL translocator]

1

0

High-throughput

0.279

Low

501295

RATB
UPF0125 protein RatB

1

0

High-throughput

0.279

Low

501296

FLIK
Flagellar hook-length control protein

1

0

High-throughput

0.279

Low

501302

EUTT
Corrinoid adenosyltransferase EutT

1

0

High-throughput

0.279

Low

501306

YCGZ
Probable two-component-system connector protein YcgZ

1

0

High-throughput

0.279

Low

501307

YMGA
Probable two-component-system connector protein YmgA

1

0

High-throughput

0.279

Low

501308

YDAY
Protein YdaY

1

0

High-throughput

0.279

Low

501310

DMLR
HTH-type transcriptional regulator DmlR

1

0

High-throughput

0.279

Low

501311

YOEA
Protein YoeA

1

0

High-throughput

0.279

Low

501312

MDTC
Multidrug resistance protein MdtC

1

0

High-throughput

0.279

Low

501313

YFDS
Uncharacterized protein YfdS

1

0

High-throughput

0.279

Low

501314

YPJB
Protein YpjB

1

0

High-throughput

0.279

Low

501316

WCAA
Putative colanic acid biosynthesis glycosyl transferase WcaA

1

0

High-throughput

0.279

Low

501317

RPNB
Recombination-promoting nuclease RpnB

1

0

High-throughput

0.279

Low

501300

GADE
Transcriptional regulator GadE

1

0

High-throughput

0.269

Low

494569

RNPA
Ribonuclease P protein component

1

0

High-throughput

0.253

Low

495438

TRMB
tRNA

1

0

High-throughput

0.253

Low

496060

BLC
Outer membrane lipoprotein Blc

1

0

High-throughput

0.249

Low

501291

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

501309

YNCE
Uncharacterized protein YncE

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025