Protein: PROB
Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase)

Gene: PROB, PRO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 28
UniProt ID: P32264

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004349 - glutamate 5-kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

733607

PROB
Glutamate 5-kinase

3

4

High-throughput

0.852

High

392388

HSP82
ATP-dependent molecular chaperone HSP82

2

3

High-throughput

0.614

High

733617

IST1
Vacuolar protein sorting-associated protein IST1

2

0

High-throughput

0.563

High

460959

LTE1
Guanine nucleotide exchange factor LTE1

1

1

High-throughput

0.536

High

645890

DBF2
Cell cycle protein kinase DBF2

1

2

High-throughput

0.536

High

733616

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

733613

GLE2
mRNA export factor GLE2

1

3

High-throughput

0.515

High

733619

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

733610

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2

1

0

High-throughput

0.493

High

733621

RRP9
Ribosomal RNA-processing protein 9

1

2

High-throughput

0.489

High

733611

KOG1
Target of rapamycin complex 1 subunit KOG1

1

2

High-throughput

0.481

High

579015

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

558630

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

571346

CPYI
Carboxypeptidase Y inhibitor

1

0

Small-scale

0.458

High

733608

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

733612

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

733615

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

733620

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

733622

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

733623

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

733614

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

430804

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

High-throughput

0.438

High

733609

DOM34
Protein DOM34

1

0

High-throughput

0.426

High

381936

H4
Histone H4

2

0

High-throughput

0.324

High

449283

RAD10
DNA repair protein RAD10

1

0

High-throughput

0.279

Low

733618

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.279

Low

706452

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025