Protein: SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

Gene: SNU66
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: Q12420

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000481 - maturation of 5S rRNA
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0045292 - mRNA cis splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1015583

HUB1
Ubiquitin-like modifier HUB1

4

2

Small-scale

0.908

High

697281

BRR2
Pre-mRNA-splicing helicase BRR2

10

3

Small-scale

0.755

High

704740

PRP8
Pre-mRNA-splicing factor 8

5

1

Small-scale

0.714

High

589111

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

4

4

Small-scale

0.691

High

976058

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

4

1

Small-scale

0.691

High

586455

PRP6
Pre-mRNA-splicing factor 6

4

3

Small-scale

0.684

High

830835

PRP31
Pre-mRNA-processing factor 31

5

0

Small-scale

0.684

High

766980

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

2

Small-scale

0.683

High

770351

RUXG
Small nuclear ribonucleoprotein G

4

7

Small-scale

0.678

High

811676

LSM8
U6 snRNA-associated Sm-like protein LSm8

4

8

Small-scale

0.678

High

884841

LSM3
U6 snRNA-associated Sm-like protein LSm3

4

11

Small-scale

0.672

High

865992

LSM7
U6 snRNA-associated Sm-like protein LSm7

3

9

Small-scale

0.662

High

747731

SP381
Pre-mRNA-splicing factor SPP381

4

0

Small-scale

0.661

High

746371

LSM2
U6 snRNA-associated Sm-like protein LSm2

3

4

Small-scale

0.656

High

767849

LSM4
U6 snRNA-associated Sm-like protein LSm4

3

2

Small-scale

0.656

High

731791

SN114
Pre-mRNA-splicing factor SNU114

3

1

Small-scale

0.650

High

795438

SMD3
Small nuclear ribonucleoprotein Sm D3

3

4

Small-scale

0.650

High

987148

LSM6
U6 snRNA-associated Sm-like protein LSm6

2

3

Small-scale

0.611

High

548568

GCN2
eIF-2-alpha kinase GCN2

2

0

High-throughput

0.595

High

692443

PRP21
Pre-mRNA-splicing factor PRP21

2

1

Small-scale

0.584

High

873683

RUXF
Small nuclear ribonucleoprotein F

2

3

Small-scale

0.584

High

986613

SMD2
Small nuclear ribonucleoprotein Sm D2

2

1

Small-scale

0.584

High

991160

PRP11
Pre-mRNA-splicing factor PRP11

2

1

Small-scale

0.584

High

1015487

RUXE
Small nuclear ribonucleoprotein E

2

1

Small-scale

0.584

High

692381

PRP19
Pre-mRNA-processing factor 19

2

3

Small-scale

0.571

High

961610

PRP38
Pre-mRNA-splicing factor 38

2

0

Small-scale

0.559

High

970255

SMD1
Small nuclear ribonucleoprotein Sm D1

2

0

Small-scale

0.559

High

989235

DIB1
Spliceosomal protein DIB1

2

0

Small-scale

0.559

High

997049

RU2A
U2 small nuclear ribonucleoprotein A'

2

0

Small-scale

0.559

High

1015529

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

0

Small-scale

0.559

High

691444

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

2

2

High-throughput

0.537

High

532836

MSI1
Chromatin assembly factor 1 subunit p50

1

2

High-throughput

0.536

High

744717

TAF5
Transcription initiation factor TFIID subunit 5

1

3

High-throughput

0.536

High

544627

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.521

High

643219

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

0

High-throughput

0.513

High

864709

NOG2
Nucleolar GTP-binding protein 2

1

0

Small-scale

0.486

High

797678

SAD1
Pre-mRNA-splicing factor SAD1

1

1

Small-scale

0.481

High

367113

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

703294

PRP40
Pre-mRNA-processing protein PRP40

1

2

Small-scale

0.479

High

710242

NCBP1
Nuclear cap-binding protein complex subunit 1

1

1

Small-scale

0.479

High

763257

PRP39
Pre-mRNA-processing factor 39

1

3

Small-scale

0.479

High

766371

SNU13
13 kDa ribonucleoprotein-associated protein

1

2

Small-scale

0.479

High

768264

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

1

Small-scale

0.479

High

775733

MSL1
U2 small nuclear ribonucleoprotein B''

1

4

Small-scale

0.479

High

836953

SF3B1
U2 snRNP component HSH155

1

1

Small-scale

0.479

High

859467

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

1

Small-scale

0.479

High

962605

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

1

Small-scale

0.479

High

977091

CEF1
Pre-mRNA-splicing factor CEF1

1

1

Small-scale

0.479

High

996595

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.479

High

1015446

CLF1
Pre-mRNA-splicing factor CLF1

1

3

Small-scale

0.479

High

653138

MIG1
Regulatory protein MIG1

1

0

Small-scale

0.460

High

972941

IMA1
Importin subunit alpha

1

0

Small-scale

0.460

High

469795

YSF3
RDS3 complex subunit 10

1

0

Small-scale

0.458

High

586544

PRP9
Pre-mRNA-splicing factor PRP9

1

0

Small-scale

0.458

High

606184

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

663724

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

696680

RU1A
U1 small nuclear ribonucleoprotein A

1

0

Small-scale

0.458

High

733106

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

746890

SLT11
Pre-mRNA-splicing factor SLT11

1

0

Small-scale

0.458

High

860163

SNU71
U1 small nuclear ribonucleoprotein component SNU71

1

0

Small-scale

0.458

High

960484

NAM8
Protein NAM8

1

0

Small-scale

0.458

High

971708

CUS1
Cold sensitive U2 snRNA suppressor 1

1

0

Small-scale

0.458

High

977620

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

1

0

Small-scale

0.458

High

980242

RSE1
Pre-mRNA-splicing factor RSE1

1

0

Small-scale

0.458

High

989437

RDS3
Pre-mRNA-splicing factor RDS3

1

0

Small-scale

0.458

High

991489

LUC7
Protein LUC7

1

0

Small-scale

0.458

High

1014862

MDN1
Midasin

1

0

High-throughput

0.458

High

1015180

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

1015584

HSH49
Protein HSH49

1

0

Small-scale

0.458

High

450243

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

492899

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

495356

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

695849

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

696108

HSP79
Heat shock protein homolog SSE2

1

4

High-throughput

0.445

High

754827

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

599390

CBP3
Protein CBP3, mitochondrial

1

0

Small-scale

0.251

Low

692268

PT309
Pentatricopeptide repeat-containing protein PET309, mitochondrial

1

0

Small-scale

0.251

Low

389163

SYWM
Tryptophan--tRNA ligase, mitochondrial

1

0

High-throughput

0.238

Low

629085

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.232

Low

692647

ZUO1
Zuotin

1

0

High-throughput

0.232

Low

705828

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

766287

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024