Protein: CO8A1
Collagen alpha-1(VIII) chain (Endothelial collagen) [Cleaved into: Vastatin]

Gene: CO8A1, COL8A1
Organism: Homo sapiens
Interactions: 131
UniProt ID: P27658

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001935 - endothelial cell proliferation
GO:0005576 - extracellular region
GO:0005591 - collagen type VIII trimer
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

358600

CO2A1
Collagen alpha-1(II) chain

1

19

High-throughput

0.691

High

358656

CO4A1

1

18

High-throughput

0.691

High

596154

CO5A1

1

19

High-throughput

0.691

High

650067

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

19

High-throughput

0.691

High

650119

C1QL4
Complement C1q-like protein 4

1

20

High-throughput

0.691

High

626306

CO8A2
Collagen alpha-2(VIII) chain

1

17

Small-scale

0.647

High

650085

VAC14
Protein VAC14 homolog

4

3

High-throughput

0.644

High

650118

NT2NA
Notch homolog 2 N-terminal-like protein A

2

2

High-throughput

0.633

High

650077

KR108
Keratin-associated protein 10-8

3

6

High-throughput

0.616

High

650068

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

2

1

High-throughput

0.606

High

650071

CCN3
CCN family member 3

2

1

High-throughput

0.606

High

650080

FBLN2
Fibulin-2

2

3

High-throughput

0.606

High

650128

WFDC5
WAP four-disulfide core domain protein 5

2

0

High-throughput

0.580

High

650150

BPIA1
BPI fold-containing family A member 1

2

0

High-throughput

0.580

High

650154

KRT82
Keratin, type II cuticular Hb2

2

0

High-throughput

0.580

High

180970

GSC2
Homeobox protein goosecoid-2

2

5

High-throughput

0.553

High

280356

GLRX3
Glutaredoxin-3

2

8

High-throughput

0.553

High

280856

KRT37
Keratin, type I cuticular Ha7

2

2

High-throughput

0.553

High

642015

KRA59
Keratin-associated protein 5-9

2

8

High-throughput

0.553

High

650066

OTX1
Homeobox protein OTX1

2

4

High-throughput

0.553

High

650096

KR133
Keratin-associated protein 13-3

2

1

High-throughput

0.553

High

650107

KRA57
Keratin-associated protein 5-7

2

7

High-throughput

0.553

High

650110

ZN774
Zinc finger protein 774

2

2

High-throughput

0.553

High

650121

KRA13
Keratin-associated protein 1-3

2

7

High-throughput

0.553

High

650133

ARMC5
Armadillo repeat-containing protein 5

2

1

High-throughput

0.553

High

650142

KRA93
Keratin-associated protein 9-3

2

7

High-throughput

0.553

High

650163

CIDEB
Lipid transferase CIDEB

2

1

High-throughput

0.553

High

650164

UBQL2
Ubiquilin-2

2

6

High-throughput

0.553

High

650167

TRI35
E3 ubiquitin-protein ligase TRIM35

2

1

High-throughput

0.553

High

327953

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

4

High-throughput

0.541

High

650114

ATL4
ADAMTS-like protein 4

1

0

High-throughput

0.536

High

180007

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

8

High-throughput

0.536

High

274407

CRTAP
Cartilage-associated protein

1

14

High-throughput

0.536

High

532058

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

8

High-throughput

0.536

High

650088

ELOA1
Elongin-A

1

3

High-throughput

0.536

High

650090

P3H1
Prolyl 3-hydroxylase 1

1

14

High-throughput

0.536

High

650122

GT252
Procollagen galactosyltransferase 2

1

20

High-throughput

0.536

High

650076

KR107
Keratin-associated protein 10-7

1

7

High-throughput

0.523

High

650081

SP4
Transcription factor Sp4

1

4

High-throughput

0.523

High

650083

REL
Proto-oncogene c-Rel

1

1

High-throughput

0.523

High

650105

K1C40
Keratin, type I cytoskeletal 40

1

2

High-throughput

0.523

High

650143

KRA92
Keratin-associated protein 9-2

1

7

High-throughput

0.523

High

484570

NT2NC
Notch homolog 2 N-terminal-like protein C

1

2

High-throughput

0.515

High

650101

HABP4
Intracellular hyaluronan-binding protein 4

1

0

High-throughput

0.513

High

650148

ESF1
ESF1 homolog

1

0

High-throughput

0.513

High

650099

KLH12
Kelch-like protein 12

1

5

High-throughput

0.494

High

650139

KR412
Keratin-associated protein 4-12

1

7

High-throughput

0.494

High

650152

UBQL4
Ubiquilin-4

1

6

High-throughput

0.494

High

135576

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

1

High-throughput

0.489

High

650070

PRC2A
Protein PRRC2A

1

5

High-throughput

0.489

High

650117

DDX46
Probable ATP-dependent RNA helicase DDX46

1

1

High-throughput

0.489

High

650138

IWS1
Protein IWS1 homolog

1

2

High-throughput

0.489

High

650141

DIDO1
Death-inducer obliterator 1

1

14

High-throughput

0.489

High

650151

DISC1
Disrupted in schizophrenia 1 protein

1

6

High-throughput

0.489

High

650169

WBP11
WW domain-binding protein 11

1

3

High-throughput

0.489

High

650129

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

1

High-throughput

0.481

High

362846

FINC
Fibronectin

1

20

Small-scale

0.479

High

650140

Q9BS75
KLHL20 protein

1

6

High-throughput

0.470

High

122507

MEN1
Menin

1

0

High-throughput

0.458

High

650075

KR103
Keratin-associated protein 10-3

1

7

High-throughput

0.439

High

650120

KR131
Keratin-associated protein 13-1

1

1

High-throughput

0.439

High

650168

KLH20
Kelch-like protein 20

1

6

High-throughput

0.439

High

100505

APRIO
Alternative prion protein

1

6

High-throughput

0.437

High

345986

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.437

High

650069

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.437

High

650104

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.437

High

650115

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.437

High

650089

SF01
Splicing factor 1

1

1

High-throughput

0.417

High

650086

INCA1
Protein INCA1

4

0

High-throughput

0.364

High

650082

CREB5
Cyclic AMP-responsive element-binding protein 5

3

0

High-throughput

0.352

High

283164

RGS20
Regulator of G-protein signaling 20

3

0

High-throughput

0.339

High

66990

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

199172

ZNHI1
Zinc finger HIT domain-containing protein 1

2

0

High-throughput

0.316

High

207297

FRS3
Fibroblast growth factor receptor substrate 3

2

0

High-throughput

0.316

High

650072

HXA1
Homeobox protein Hox-A1

2

0

High-throughput

0.316

High

650074

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.316

High

650079

S35A2
UDP-galactose translocator

2

0

High-throughput

0.316

High

650087

PO4F2
POU domain, class 4, transcription factor 2

2

0

High-throughput

0.316

High

650091

MAJIN
Membrane-anchored junction protein

2

0

High-throughput

0.316

High

650092

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.316

High

650093

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

650095

KR195
Keratin-associated protein 19-5

2

0

High-throughput

0.316

High

650097

KR197
Keratin-associated protein 19-7

2

0

High-throughput

0.316

High

650098

CEP55
Centrosomal protein of 55 kDa

2

0

High-throughput

0.316

High

650100

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

650103

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

650106

NADE
Glutamine-dependent NAD(+) synthetase

2

0

High-throughput

0.316

High

650108

KRA56
Keratin-associated protein 5-6

2

0

High-throughput

0.316

High

650109

RHBD2
Rhomboid domain-containing protein 2

2

0

High-throughput

0.316

High

650111

CV039
Synaptic plasticity regulator PANTS

2

0

High-throughput

0.316

High

650113

SPAT8
Spermatogenesis-associated protein 8

2

0

High-throughput

0.316

High

650124

SMIP6
Sperm microtubule inner protein 6

2

0

High-throughput

0.316

High

650131

POF1B
Protein POF1B

2

0

High-throughput

0.316

High

650132

RBPMS
RNA-binding protein with multiple splicing

2

0

High-throughput

0.316

High

650144

KRA32
Keratin-associated protein 3-2

2

0

High-throughput

0.316

High

650146

SPY4
Protein sprouty homolog 4

2

0

High-throughput

0.316

High

650149

CFA68
Cilia- and flagella-associated protein 68

2

0

High-throughput

0.316

High

650153

PLS3
Phospholipid scramblase 3

2

0

High-throughput

0.316

High

650158

F86C1
Putative protein FAM86C1P

2

0

High-throughput

0.316

High

650159

FBX34
F-box only protein 34

2

0

High-throughput

0.316

High

650112

KR261
Keratin-associated protein 26-1

1

0

High-throughput

0.303

High

63726

CC85C
Coiled-coil domain-containing protein 85C

1

0

High-throughput

0.279

Low

534063

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.279

Low

650102

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

0

High-throughput

0.279

Low

650116

CENPU
Centromere protein U

1

0

High-throughput

0.279

Low

650123

NF2IP
NFATC2-interacting protein

1

0

High-throughput

0.279

Low

650125

LS14A
Protein LSM14 homolog A

1

0

High-throughput

0.279

Low

650126

RP9
Retinitis pigmentosa 9 protein

1

0

High-throughput

0.279

Low

650127

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.279

Low

650130

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.279

Low

650134

REPS1
RalBP1-associated Eps domain-containing protein 1

1

0

High-throughput

0.279

Low

650135

RMXL1
RNA binding motif protein, X-linked-like-1

1

0

High-throughput

0.279

Low

650136

RRP36
Ribosomal RNA processing protein 36 homolog

1

0

High-throughput

0.279

Low

650137

ZC21A
Zinc finger C2HC domain-containing protein 1A

1

0

High-throughput

0.279

Low

650145

GTPB4
GTP-binding protein 4

1

0

High-throughput

0.279

Low

650147

LSG1
Large subunit GTPase 1 homolog

1

0

High-throughput

0.279

Low

650155

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

High-throughput

0.279

Low

650156

BMP2K
BMP-2-inducible protein kinase

1

0

High-throughput

0.279

Low

650157

DCA13
DDB1- and CUL4-associated factor 13

1

0

High-throughput

0.279

Low

650160

CWC25
Pre-mRNA-splicing factor CWC25 homolog

1

0

High-throughput

0.279

Low

650161

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

0

High-throughput

0.279

Low

650162

ZO2
Tight junction protein ZO-2

1

0

High-throughput

0.279

Low

650166

NOB1
RNA-binding protein NOB1

1

0

High-throughput

0.279

Low

417959

NPM
Nucleophosmin

1

0

High-throughput

0.269

Low

3519

DP2NB
DPEP2 neighbor protein

1

0

High-throughput

0.268

Low

650094

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

482

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.251

Low

650078

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

650084

PPARA
Peroxisome proliferator-activated receptor alpha

1

0

High-throughput

0.251

Low

650073

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.249

Low

650165

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024