Protein: FOLE
Folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase)

Gene: FOLE, MET7
Organism: Saccharomyces cerevisiae S288C
Interactions: 24
UniProt ID: Q08645

Gene Ontology (top 5):
GO:0004326 - tetrahydrofolylpolyglutamate synthase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1064627

FOLE
Folylpolyglutamate synthase

2

0

High-throughput

0.551

High

815597

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

Small-scale

0.480

High

1028039

ACAC
Acetyl-CoA carboxylase

1

0

Small-scale

0.460

High

518412

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.458

High

638741

RIR1
Ribonucleoside-diphosphate reductase large chain 1

1

0

Small-scale

0.458

High

525396

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

527889

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

546570

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

742567

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

820000

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

386894

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

394968

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

592548

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

684868

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

814407

NOC2
Nucleolar complex protein 2

1

0

High-throughput

0.426

High

871455

HLJ1
Protein HLJ1

1

0

High-throughput

0.426

High

1043304

HAS1
ATP-dependent RNA helicase HAS1

1

0

High-throughput

0.426

High

750315

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.261

Low

677598

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

708405

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

672511

YCP2
Uncharacterized protein YCR001W

1

0

High-throughput

0.238

Low

575532

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

917575

NSA1
Ribosome biogenesis protein NSA1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025