Protein: PEX3
Peroxisomal biogenesis factor 3 (Peroxin-3)

Gene: PEX3
Organism: Saccharomyces cerevisiae S288C
Interactions: 172
UniProt ID: P28795

Gene Ontology (top 5):
GO:0005777 - peroxisome
GO:0005778 - peroxisomal membrane
GO:0005783 - endoplasmic reticulum
GO:0030674 - protein-macromolecule adaptor activity
GO:0032581 - ER-dependent peroxisome organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

705134

PEX3
Peroxisomal biogenesis factor 3

4

0

Small-scale

0.828

High

705227

PEX19
Peroxisomal membrane protein import receptor PEX19

8

0

Small-scale

0.716

High

705218

INP1
Inheritance of peroxisomes protein 1

5

0

Small-scale

0.689

High

705231

PEX15
Peroxisomal membrane protein PEX15

4

0

Small-scale

0.661

High

705194

ATG36
Autophagy-related protein 36

3

0

Small-scale

0.640

High

705217

PEX25
Peroxisomal membrane protein PEX25

2

1

High-throughput

0.614

High

705216

PEX13
Peroxisomal membrane protein PEX13

2

0

Small-scale

0.588

High

705236

PEX11
Peroxisomal membrane protein PMP27

2

0

High-throughput

0.588

High

705233

PEX27
Peroxisomal membrane protein PEX27

2

1

High-throughput

0.576

High

705155

PEX5
Peroxisomal targeting signal receptor

2

0

Small-scale

0.559

High

623787

MYO2
Myosin-2

1

0

Small-scale

0.480

High

366042

CBPY
Carboxypeptidase Y

1

2

High-throughput

0.479

High

663768

PEX1
Peroxisomal ATPase PEX1

1

1

High-throughput

0.479

High

671348

PHO84
Inorganic phosphate transporter PHO84

1

1

High-throughput

0.479

High

673281

ADP1
Probable ATP-dependent permease

1

1

High-throughput

0.479

High

705154

PEX6
Peroxisomal ATPase PEX6

1

1

High-throughput

0.479

High

705165

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

1

3

High-throughput

0.479

High

705198

GNP1
High-affinity glutamine permease

1

3

High-throughput

0.479

High

705211

KTR6
Mannosyltransferase KTR6

1

2

High-throughput

0.479

High

705237

ATC4
Phospholipid-transporting ATPase DNF2

1

1

High-throughput

0.479

High

705206

YG3W
Uncharacterized protein YGR168C

1

0

Small-scale

0.460

High

454280

CARP
Saccharopepsin

1

0

High-throughput

0.458

High

569384

DPM1
Dolichol-phosphate mannosyltransferase

1

0

High-throughput

0.458

High

613538

ADT2
ADP,ATP carrier protein 2

1

0

High-throughput

0.458

High

705135

CHIT
Endochitinase

1

0

High-throughput

0.458

High

705152

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.458

High

705168

KMO
Kynurenine 3-monooxygenase

1

0

High-throughput

0.458

High

705170

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

705175

FET3
Iron transport multicopper oxidase FET3

1

0

High-throughput

0.458

High

705178

PEX22
Peroxisome assembly protein 22

1

0

High-throughput

0.458

High

705184

PEX17
Peroxisomal membrane protein PEX17

1

0

High-throughput

0.458

High

705186

AYR1
NADPH-dependent 1-acyldihydroxyacetone phosphate reductase

1

0

High-throughput

0.458

High

705193

GYP8
GTPase-activating protein GYP8

1

0

High-throughput

0.458

High

705203

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

705207

SAY1
Steryl acetyl hydrolase 1

1

0

High-throughput

0.458

High

705220

PEX12
Peroxisome assembly protein 12

1

0

High-throughput

0.458

High

705222

RTN1
Reticulon-like protein 1

1

0

High-throughput

0.458

High

705224

ANT1
Peroxisomal adenine nucleotide transporter 1

1

0

High-throughput

0.458

High

705225

CSC1
Calcium permeable stress-gated cation channel 1

1

0

High-throughput

0.458

High

358141

ADH1
Alcohol dehydrogenase 1

1

1

High-throughput

0.437

High

358979

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.437

High

359168

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

1

High-throughput

0.437

High

367710

ENO1
Enolase 1

1

1

High-throughput

0.437

High

367916

ENO2
Enolase 2

1

1

High-throughput

0.437

High

452638

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

1

High-throughput

0.437

High

452844

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

484269

KEX1
Pheromone-processing carboxypeptidase KEX1

1

2

High-throughput

0.437

High

592066

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.437

High

600637

FCY2
Purine-cytosine permease FCY2

1

1

High-throughput

0.437

High

603423

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.437

High

698132

KRE2
Glycolipid 2-alpha-mannosyltransferase

1

2

High-throughput

0.437

High

698162

KTR1
Alpha-1,2 mannosyltransferase KTR1

1

2

High-throughput

0.437

High

705140

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

1

High-throughput

0.437

High

705144

LYP1
Lysine-specific permease

1

3

High-throughput

0.437

High

705145

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

1

High-throughput

0.437

High

705148

PEP12
Syntaxin PEP12

1

1

High-throughput

0.437

High

705153

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

1

High-throughput

0.437

High

705157

VPS21
Vacuolar protein sorting-associated protein 21

1

1

High-throughput

0.437

High

705159

VPS24
Vacuolar protein-sorting-associated protein 24

1

2

High-throughput

0.437

High

705160

DID4
DOA4-independent degradation protein 4

1

2

High-throughput

0.437

High

705162

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

1

High-throughput

0.437

High

705166

ATG42
Vacuolar serine-type carboxypeptidase ATG42

1

2

High-throughput

0.437

High

705169

FUI1
Uridine permease

1

1

High-throughput

0.437

High

705171

FKS1
1,3-beta-glucan synthase component FKS1

1

1

High-throughput

0.437

High

705177

UIP3
ULP1-interacting protein 3

1

1

High-throughput

0.437

High

705179

SNF7
Vacuolar-sorting protein SNF7

1

1

High-throughput

0.437

High

705181

SIT1
Siderophore iron transporter 1

1

2

High-throughput

0.437

High

705185

VTH1
VPS10 homolog 1

1

1

High-throughput

0.437

High

705187

ATC7
Phospholipid-transporting ATPase NEO1

1

1

High-throughput

0.437

High

705189

PHB1
Prohibitin-1

1

1

High-throughput

0.437

High

705191

FKS2
1,3-beta-glucan synthase component GSC2

1

1

High-throughput

0.437

High

705200

PHB2
Prohibitin-2

1

1

High-throughput

0.437

High

705201

MUP1
High-affinity methionine permease

1

4

High-throughput

0.437

High

705202

TPN1
Vitamin B6 transporter TPN1

1

1

High-throughput

0.437

High

705208

COS6
Protein COS6

1

1

High-throughput

0.437

High

705209

DIP5
Dicarboxylic amino acid permease

1

3

High-throughput

0.437

High

705210

AQR1
Probable transporter AQR1

1

1

High-throughput

0.437

High

705215

DID2
Vacuolar protein-sorting-associated protein 46

1

2

High-throughput

0.437

High

705223

THI7
Thiamine transporter

1

1

High-throughput

0.437

High

705230

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

1

High-throughput

0.437

High

705232

AUS1
ATP-dependent permease AUS1

1

1

High-throughput

0.437

High

661769

TOM40
Mitochondrial import receptor subunit TOM40

1

0

High-throughput

0.282

High

705164

BOI1
BEM1-interacting protein 1

1

0

High-throughput

0.282

High

705161

PET10
Protein PET10

1

0

High-throughput

0.251

Low

364962

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.249

Low

365574

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.249

Low

368416

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.249

Low

368613

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.249

Low

376276

YPT1
GTP-binding protein YPT1

1

0

High-throughput

0.249

Low

381435

H2B2
Histone H2B.2

1

0

High-throughput

0.249

Low

381921

H4
Histone H4

1

0

High-throughput

0.249

Low

394314

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.249

Low

417044

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.249

Low

420893

PMA1
Plasma membrane ATPase 1

1

0

High-throughput

0.249

Low

434892

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

436344

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.249

Low

439273

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.249

Low

441754

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

451997

TOM70
Mitochondrial import receptor subunit TOM70

1

0

High-throughput

0.249

Low

510269

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.249

Low

512031

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.249

Low

513649

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

514933

YA11A
Transposon Ty1-A Gag polyprotein

1

0

High-throughput

0.249

Low

515059

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

518230

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.249

Low

523268

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.249

Low

544065

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.249

Low

554887

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.249

Low

555025

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.249

Low

569930

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

572532

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.249

Low

578217

TAL1
Transaldolase

1

0

High-throughput

0.249

Low

578982

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

590559

HSP26
Heat shock protein 26

1

0

High-throughput

0.249

Low

594899

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

598309

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.249

Low

616394

SEC18
Vesicular-fusion protein SEC18

1

0

High-throughput

0.249

Low

617962

DAP2
Dipeptidyl aminopeptidase B

1

0

High-throughput

0.249

Low

626632

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.249

Low

647714

RFA1
Replication factor A protein 1

1

0

High-throughput

0.249

Low

655407

RS3A2
Small ribosomal subunit protein eS1B

1

0

High-throughput

0.249

Low

661589

MPCP
Mitochondrial phosphate carrier protein

1

0

High-throughput

0.249

Low

674464

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

675777

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.249

Low

688837

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.249

Low

693482

CBPS
Carboxypeptidase S

1

0

High-throughput

0.249

Low

705136

HRR25
Casein kinase I homolog HRR25

1

0

Small-scale

0.249

Low

705137

PTP2
Tyrosine-protein phosphatase 2

1

0

High-throughput

0.249

Low

705138

SNC1
Synaptobrevin homolog 1

1

0

High-throughput

0.249

Low

705139

STX8
Syntaxin-8

1

0

High-throughput

0.249

Low

705141

EF2
Elongation factor 2

1

0

High-throughput

0.249

Low

705142

VA0D
V-type proton ATPase subunit d

1

0

High-throughput

0.249

Low

705143

HXT3
Low-affinity glucose transporter HXT3

1

0

High-throughput

0.249

Low

705146

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.249

Low

705147

MG101
Mitochondrial genome maintenance protein MGM101

1

0

High-throughput

0.249

Low

705149

PTM1
Membrane protein PTM1

1

0

High-throughput

0.249

Low

705150

SSO1
Protein SSO1

1

0

High-throughput

0.249

Low

705151

PTR2
Peptide transporter PTR2

1

0

High-throughput

0.249

Low

705156

YKT6
Synaptobrevin homolog YKT6

1

0

High-throughput

0.249

Low

705158

MCR1
NADH-cytochrome b5 reductase 2

1

0

High-throughput

0.249

Low

705163

APE3
Aminopeptidase Y

1

0

High-throughput

0.249

Low

705167

ATR
Serine/threonine-protein kinase MEC1

1

0

High-throughput

0.249

Low

705172

RS27B
Small ribosomal subunit protein eS27B

1

0

High-throughput

0.249

Low

705173

RL14B
Large ribosomal subunit protein eL14B

1

0

High-throughput

0.249

Low

705174

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

0

High-throughput

0.249

Low

705176

PHO90
Low-affinity phosphate transporter PHO90

1

0

High-throughput

0.249

Low

705180

RS26A
Small ribosomal subunit protein eS26A

1

0

High-throughput

0.249

Low

705182

ICP55
Intermediate cleaving peptidase 55

1

0

High-throughput

0.249

Low

705183

FTR1
Plasma membrane iron permease

1

0

High-throughput

0.249

Low

705188

OPT1
Oligopeptide transporter 1

1

0

High-throughput

0.249

Low

705190

FET4
Low-affinity Fe(2+) transport protein

1

0

High-throughput

0.249

Low

705192

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.249

Low

705195

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.249

Low

705196

IML2
Inclusion body clearance protein IML2

1

0

High-throughput

0.249

Low

705197

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

705199

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.249

Low

705204

RL26B
Large ribosomal subunit protein uL24B

1

0

High-throughput

0.249

Low

705205

VOA1
V0 assembly protein 1

1

0

High-throughput

0.249

Low

705212

ALO
D-arabinono-1,4-lactone oxidase

1

0

High-throughput

0.249

Low

705213

ACT
Actin

1

0

High-throughput

0.249

Low

705214

H3
Histone H3

1

0

High-throughput

0.249

Low

705219

VTI1
t-SNARE VTI1

1

0

High-throughput

0.249

Low

705221

LCD1
DNA damage checkpoint protein LCD1

1

0

High-throughput

0.249

Low

705226

YL413
Cell membrane protein YLR413W

1

0

High-throughput

0.249

Low

705228

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

705234

FSF1
Sideroflexin FSF1

1

0

High-throughput

0.249

Low

705235

ATO3
Ammonia transport outward protein 3

1

0

High-throughput

0.249

Low

705238

ATN5
Sodium/potassium exporting P-type ATPase 5

1

0

High-throughput

0.249

Low

705239

H2AZ
Histone H2A.Z

1

0

High-throughput

0.249

Low

705240

RS25A
Small ribosomal subunit protein eS25A

1

0

High-throughput

0.249

Low

705229

NOC3
Nucleolar complex-associated protein 3

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025