Protein: GSF2
Glucose-signaling factor 2 (Extracellular mutant protein 6)

Gene: GSF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 125
UniProt ID: Q04697

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005741 - mitochondrial outer membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006457 - protein folding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

580044

HSC82
ATP-dependent molecular chaperone HSC82

3

1

High-throughput

0.633

High

916777

ERG25
C-4 methylsterol oxidase ERG25

2

2

High-throughput

0.614

High

546231

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.611

High

822339

ELO3
Fatty acid elongase 3

2

0

High-throughput

0.588

High

441247

KAPA
cAMP-dependent protein kinase type 1

2

0

High-throughput

0.577

High

692432

KCC1
Calcium/calmodulin-dependent protein kinase I

2

0

High-throughput

0.577

High

1047501

GSF2
Glucose-signaling factor 2

2

0

High-throughput

0.561

High

416724

CAN1
Arginine permease CAN1

1

4

High-throughput

0.541

High

671390

PHO84
Inorganic phosphate transporter PHO84

1

6

High-throughput

0.541

High

673445

AGP1
General amino acid permease AGP1

1

4

High-throughput

0.541

High

745391

EMP24
Endosomal protein P24B

1

1

High-throughput

0.541

High

751832

SGE1
Protein SGE1

1

7

High-throughput

0.541

High

793279

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

1

4

High-throughput

0.541

High

798668

SSH1
Sec sixty-one protein homolog

1

1

High-throughput

0.541

High

803042

YHE2
Putative uncharacterized protein YHL042W

1

3

High-throughput

0.541

High

805336

ERP5
Protein ERP5

1

1

High-throughput

0.541

High

808696

SUR2
Sphingolipid C4-hydroxylase SUR2

1

2

High-throughput

0.541

High

849580

COS4
Protein COS4

1

3

High-throughput

0.541

High

919629

TNA1
High-affinity nicotinic acid transporter

1

6

High-throughput

0.541

High

1047509

SAM3
S-adenosylmethionine permease SAM3

1

4

High-throughput

0.541

High

1047515

MMP1
S-methylmethionine permease 1

1

4

High-throughput

0.541

High

754660

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

1

0

High-throughput

0.518

High

763812

CSG2
Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2

1

0

High-throughput

0.518

High

797450

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.518

High

797616

YPC1
Alkaline ceramidase YPC1

1

0

High-throughput

0.518

High

798726

BSD2
Metal homeostatis protein BSD2

1

0

High-throughput

0.518

High

805804

NSG1
Protein NSG1

1

0

High-throughput

0.518

High

805907

YHU0
UPF0641 membrane protein YHR140W

1

0

High-throughput

0.518

High

805931

CHS7
Chitin synthase export chaperone

1

0

High-throughput

0.518

High

808721

FET3
Iron transport multicopper oxidase FET3

1

0

High-throughput

0.518

High

863280

GPI2
Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit

1

0

High-throughput

0.518

High

863340

SPC1
Signal peptidase complex subunit 1

1

0

High-throughput

0.518

High

864901

VTC4
Vacuolar transporter chaperone complex subunit 4

1

0

High-throughput

0.518

High

878385

GPI8
GPI-anchor transamidase

1

0

High-throughput

0.518

High

1038801

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

0

High-throughput

0.518

High

1047163

ERV41
ER-derived vesicles protein ERV41

1

0

High-throughput

0.518

High

1047504

PMT7
Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7

1

0

High-throughput

0.518

High

1047508

YP264
Probable transport protein YPL264C

1

0

High-throughput

0.518

High

1047512

POM33
Pore membrane protein of 33 kDa

1

0

High-throughput

0.518

High

1047517

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.518

High

633510

PP11
Serine/threonine-protein phosphatase PP1-1

1

0

High-throughput

0.513

High

1047511

GET3
ATPase GET3

1

0

High-throughput

0.513

High

560762

KIN2
Serine/threonine-protein kinase KIN2

1

1

High-throughput

0.501

High

660515

HXT2
High-affinity glucose transporter HXT2

1

5

High-throughput

0.494

High

737251

HXT1
Low-affinity glucose transporter HXT1

1

5

High-throughput

0.494

High

745967

UGA4
GABA-specific permease

1

5

High-throughput

0.494

High

794384

MAL31
Maltose permease MAL31

1

6

High-throughput

0.494

High

802048

HXT5
Probable glucose transporter HXT5

1

5

High-throughput

0.494

High

803010

COS8
Protein COS8

1

3

High-throughput

0.494

High

828589

HXT9
Hexose transporter HXT9

1

5

High-throughput

0.494

High

828590

HXT8
Hexose transporter HXT8

1

5

High-throughput

0.494

High

917655

VPS73
Vacuolar protein sorting-associated protein 73

1

6

High-throughput

0.494

High

919815

COS6
Protein COS6

1

3

High-throughput

0.494

High

932814

HXT11
Hexose transporter HXT11

1

5

High-throughput

0.494

High

1043521

GAS3
Probable 1,3-beta-glucanosyltransferase GAS3

1

1

High-throughput

0.494

High

1047503

TPO3
Polyamine transporter 3

1

8

High-throughput

0.494

High

1047505

TPO1
Polyamine transporter 1

1

8

High-throughput

0.494

High

1047506

GAS4
1,3-beta-glucanosyltransferase GAS4

1

1

High-throughput

0.494

High

448800

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.480

High

574739

KSS1
Mitogen-activated protein kinase KSS1

1

0

High-throughput

0.480

High

602630

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

666217

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

0

High-throughput

0.480

High

793204

AKL1
Serine/threonine-protein kinase AKL1

1

0

High-throughput

0.480

High

815569

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

High-throughput

0.480

High

822283

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

0

High-throughput

0.480

High

393315

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

525109

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.479

High

735358

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

2

High-throughput

0.479

High

748539

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.479

High

668955

ERG6
Sterol 24-C-methyltransferase ERG6

1

0

High-throughput

0.460

High

821065

LDO16
Lipid droplet organization protein LDO16

1

0

High-throughput

0.460

High

444622

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.458

High

554375

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

0

High-throughput

0.458

High

636347

ACO1
Acyl-CoA desaturase 1

1

0

High-throughput

0.458

High

671110

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

677119

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

680055

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

709976

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

715048

ERG9
Squalene synthase ERG9

1

0

High-throughput

0.458

High

727304

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

735320

ERG2
C-8 sterol isomerase ERG2

1

0

High-throughput

0.458

High

780799

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

816216

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.458

High

818199

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

0

Small-scale

0.458

High

826278

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.458

High

871446

HLJ1
Protein HLJ1

1

0

High-throughput

0.458

High

881438

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

1045185

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.458

High

1046297

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

1046689

HFD1
Fatty aldehyde dehydrogenase HFD1

1

0

High-throughput

0.458

High

1047507

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

1047513

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.458

High

800764

RCK1
Serine/threonine-protein kinase RCK1

1

1

High-throughput

0.457

High

527647

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

742371

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

819761

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

386859

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

486309

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

671707

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.426

High

836889

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

1047514

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

745305

TMN1
Transmembrane 9 superfamily member 1

1

0

High-throughput

0.282

High

828594

VTH2
VPS10 homolog 2

1

0

High-throughput

0.282

High

830043

PMP2
Plasma membrane ATPase proteolipid 2

1

0

High-throughput

0.282

High

874224

TOS6
Protein TOS6

1

0

High-throughput

0.282

High

898925

AVT4
Vacuolar amino acid transporter 4

1

0

High-throughput

0.282

High

1047516

POM34
Nucleoporin POM34

1

0

High-throughput

0.282

High

561710

HAP3
Transcriptional activator HAP3

1

0

High-throughput

0.279

Low

750302

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.261

Low

917944

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.261

Low

1047502

ISR1
Serine/threonine-protein kinase ISR1

1

0

High-throughput

0.261

Low

1047510

RTK1
Probable serine/threonine-protein kinase RTK1

1

0

High-throughput

0.261

Low

782037

PET10
Protein PET10

1

0

High-throughput

0.251

Low

64280

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.249

Low

647219

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

708145

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

758467

YKK0
Probable intramembrane protease YKL100C

1

0

High-throughput

0.249

Low

779983

EMC3
ER membrane protein complex subunit 3

1

0

Small-scale

0.249

Low

812644

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

826078

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.249

Low

826825

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

844606

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

918989

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

922118

COPA
Coatomer subunit alpha

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025