Protein: HST4
NAD-dependent histone deacetylase HST4 (EC 2.3.1.286) (Homologous to SIR2 protein 4) (Regulatory protein SIR2 homolog 4)

Gene: HST4
Organism: Saccharomyces cerevisiae S288C
Interactions: 14
UniProt ID: P53688

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000183 - rDNA heterochromatin formation
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

460739

CDC4
Cell division control protein 4

2

9

Small-scale

0.611

High

922671

HST4
NAD-dependent histone deacetylase HST4

1

13

High-throughput

0.575

High

922673

SKM1
Serine/threonine-protein kinase SKM1

1

6

High-throughput

0.501

High

910763

SKP1
Suppressor of kinetochore protein 1

1

0

Small-scale

0.480

High

709899

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

393113

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.445

High

524715

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.445

High

527311

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

545755

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.445

High

670313

NAP1
Nucleosome assembly protein

1

4

High-throughput

0.445

High

863359

NMD5
Nonsense-mediated mRNA decay protein 5

1

8

High-throughput

0.445

High

922672

SXM1
Importin beta SMX1

1

7

High-throughput

0.445

High

454310

CARP
Saccharopepsin

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025