Protein: NMD5
Nonsense-mediated mRNA decay protein 5 (Karyopherin-119)

Gene: NMD5
Organism: Saccharomyces cerevisiae S288C
Interactions: 74
UniProt ID: P46970

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006606 - protein import into nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

745796

GSP1
GTP-binding nuclear protein GSP1/CNR1

3

20

Small-scale

0.840

High

382184

H4
Histone H4

2

3

High-throughput

0.621

High

779274

CENPA
Histone H3-like centromeric protein CSE4

1

5

High-throughput

0.618

High

579636

HSC82
ATP-dependent molecular chaperone HSC82

2

9

High-throughput

0.611

High

623884

MYO2
Myosin-2

2

0

High-throughput

0.595

High

863360

CRZ1
Transcriptional regulator CRZ1

2

20

Small-scale

0.576

High

545361

SSB1
Ribosome-associated molecular chaperone SSB1

2

11

High-throughput

0.552

High

392951

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.541

High

416890

CDC25
Cell division control protein 25

1

1

High-throughput

0.541

High

386765

TBB
Tubulin beta chain

1

4

High-throughput

0.536

High

470146

SPS1
Sporulation-specific protein 1

1

9

High-throughput

0.536

High

486232

TBA1
Tubulin alpha-1 chain

1

3

High-throughput

0.536

High

755123

GCN1
eIF-2-alpha kinase activator GCN1

1

8

High-throughput

0.536

High

843146

LEM3
Phospholipid-transporting ATPase accessory subunit LEM3

1

2

High-throughput

0.536

High

863368

MDN1
Midasin

1

1

High-throughput

0.536

High

863361

UBC7
Ubiquitin-conjugating enzyme E2 7

1

8

High-throughput

0.528

High

454584

TFS2
Transcription elongation factor S-II

1

1

Small-scale

0.515

High

448188

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.513

High

738667

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.513

High

863369

UPPS
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

0

High-throughput

0.513

High

863365

ASR1
Alcohol-sensitive RING finger protein 1

1

3

Small-scale

0.501

High

557740

SRS2
ATP-dependent DNA helicase SRS2

1

2

Small-scale

0.481

High

584371

GCN2
eIF-2-alpha kinase GCN2

1

5

Small-scale

0.481

High

410209

RL25
Large ribosomal subunit protein uL23

1

4

High-throughput

0.479

High

435191

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

634252

NUP1
Nucleoporin NUP1

1

20

Small-scale

0.479

High

645750

HSP74
Heat shock protein SSA4

1

13

Small-scale

0.479

High

707479

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.479

High

727140

HS104
Heat shock protein 104

1

6

High-throughput

0.479

High

738481

NUP2
Nucleoporin NUP2

1

20

Small-scale

0.479

High

793615

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

1

High-throughput

0.479

High

825156

NU159
Nucleoporin NUP159

1

20

Small-scale

0.479

High

863358

HST2
NAD-dependent protein deacetylase HST2

1

8

High-throughput

0.479

High

863363

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

863370

RIO1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.479

High

436037

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

510973

IPB2
Protease B inhibitor 2

1

0

High-throughput

0.458

High

585504

KCY
Uridylate kinase

1

0

High-throughput

0.458

High

603074

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

617423

GBG
Guanine nucleotide-binding protein subunit gamma

1

0

High-throughput

0.458

High

781324

DID4
DOA4-independent degradation protein 4

1

0

High-throughput

0.458

High

795725

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.458

High

863356

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

863366

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

805060

RPF1
Ribosome production factor 1

1

3

Small-scale

0.457

High

561253

CG13
G1/S-specific cyclin CLN3

1

3

High-throughput

0.457

High

863371

VPS5
Vacuolar protein sorting-associated protein 5

1

2

High-throughput

0.457

High

365093

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.445

High

394680

EF1A
Elongation factor 1-alpha

1

5

High-throughput

0.445

High

427336

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

453663

PYR1
Multifunctional protein URA2

1

5

High-throughput

0.445

High

518323

IF4A
ATP-dependent RNA helicase eIF4A

1

8

High-throughput

0.445

High

527025

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

548781

MCM1
Pheromone receptor transcription factor

1

1

High-throughput

0.445

High

592338

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.445

High

631957

SRP54
Signal recognition particle subunit SRP54

1

1

High-throughput

0.445

High

639033

VPS1
Vacuolar protein sorting-associated protein 1

1

4

High-throughput

0.445

High

741851

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.445

High

752432

HSP78
Heat shock protein 78, mitochondrial

1

6

High-throughput

0.445

High

836765

MPG1
Mannose-1-phosphate guanyltransferase

1

5

High-throughput

0.445

High

863359

HST4
NAD-dependent histone deacetylase HST4

1

8

High-throughput

0.445

High

781565

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.438

High

863357

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.438

High

863367

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

801694

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

1

High-throughput

0.417

High

575475

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.407

High

613863

ERD2
ER lumen protein-retaining receptor

1

1

High-throughput

0.407

High

701545

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

4

High-throughput

0.407

High

825454

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

4

High-throughput

0.407

High

863362

PDR12
ATP-dependent permease PDR12

1

3

High-throughput

0.407

High

863364

PDR15
ATP-dependent permease PDR15

1

3

High-throughput

0.407

High

745360

EMP24
Endosomal protein P24B

1

0

High-throughput

0.279

Low

598518

ALG1
Chitobiosyldiphosphodolichol beta-mannosyltransferase

1

0

High-throughput

0.249

Low

863355

MRX5
MIOREX complex component 5

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025