Protein: SKM1
Serine/threonine-protein kinase SKM1 (EC 2.7.11.1) (Protein kinase 75490 D)

Gene: SKM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 75
UniProt ID: Q12469

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000920 - septum digestion after cytokinesis
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1084516

NBP2
NAP1-binding protein 2

3

3

Small-scale

0.840

High

618368

CDC42
Cell division control protein 42

3

20

Small-scale

0.832

High

763242

PP2C1
Protein phosphatase 2C homolog 1

2

9

High-throughput

0.811

High

874278

CLA4
Serine/threonine-protein kinase CLA4

1

17

High-throughput

0.691

High

1084494

YRA1
RNA annealing protein YRA1

1

5

High-throughput

0.691

High

489020

SWI6
Regulatory protein SWI6

1

5

High-throughput

0.647

High

646102

KIN3
Serine/threonine-protein kinase KIN3

1

20

High-throughput

0.647

High

844356

ELP2
Elongator complex protein 2

1

7

High-throughput

0.647

High

924081

JJJ1
J protein JJJ1

1

10

High-throughput

0.647

High

1084174

SRO7
Lethal(2) giant larvae protein homolog SRO7

1

3

High-throughput

0.647

High

735590

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

17

High-throughput

0.618

High

917391

PCL10
PHO85 cyclin-10

1

0

High-throughput

0.614

High

1046657

MYO5
Myosin-5

1

20

High-throughput

0.590

High

801712

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

15

High-throughput

0.579

High

1084188

CWC2
Pre-mRNA-splicing factor CWC2

1

1

High-throughput

0.579

High

726193

2AAA
Protein phosphatase PP2A regulatory subunit A

1

14

High-throughput

0.536

High

1084974

MEX67
mRNA export factor MEX67

1

3

High-throughput

0.536

High

711541

BEM1
Bud emergence protein 1

1

20

Small-scale

0.527

High

368363

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

5

High-throughput

0.501

High

382429

H4
Histone H4

1

6

Small-scale

0.501

High

664478

MCM3
DNA replication licensing factor MCM3

1

8

High-throughput

0.501

High

751363

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

1

High-throughput

0.501

High

789819

SOL2
6-phosphogluconolactonase-like protein 2

1

1

High-throughput

0.501

High

796000

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

2

High-throughput

0.501

High

796691

IST2
Increased sodium tolerance protein 2

1

1

High-throughput

0.501

High

815962

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

14

High-throughput

0.501

High

816504

BUD16
Putative pyridoxal kinase BUD16

1

1

High-throughput

0.501

High

827117

YPS6
Aspartic proteinase yapsin-6

1

1

High-throughput

0.501

High

858155

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

4

High-throughput

0.501

High

858302

ARC1
tRNA-aminoacylation cofactor ARC1

1

2

High-throughput

0.501

High

865859

EAF6
Chromatin modification-related protein EAF6

1

1

High-throughput

0.501

High

919715

REXO1
RNA exonuclease 1

1

2

High-throughput

0.501

High

922673

HST4
NAD-dependent histone deacetylase HST4

1

6

High-throughput

0.501

High

924208

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

19

High-throughput

0.501

High

925459

RCM1
25S rRNA

1

2

High-throughput

0.501

High

1024999

AP2S
AP-2 complex subunit sigma

1

2

High-throughput

0.501

High

1046735

ASND1
Asparagine synthetase domain-containing protein YML096W

1

1

High-throughput

0.501

High

1084335

HOSM
Homocitrate synthase, mitochondrial

1

1

High-throughput

0.501

High

1084358

SAS10
Something about silencing protein 10

1

2

High-throughput

0.501

High

1084972

SCS22
Vesicle-associated membrane protein-associated protein SCS22

1

4

High-throughput

0.501

High

555181

G6PI
Glucose-6-phosphate isomerase

1

2

High-throughput

0.500

High

592598

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.500

High

626937

HSP60
Heat shock protein 60, mitochondrial

1

15

High-throughput

0.500

High

448842

STE3
Pheromone a factor receptor

1

0

High-throughput

0.480

High

470057

DCOR
Ornithine decarboxylase

1

0

High-throughput

0.480

High

806255

RGD3
Rho-GTPase-activating protein RGD3

1

0

High-throughput

0.480

High

865354

3HAO
3-hydroxyanthranilate 3,4-dioxygenase

1

0

High-throughput

0.480

High

923071

TR112
Multifunctional methyltransferase subunit TRM112

1

0

High-throughput

0.480

High

1043532

GAS3
Probable 1,3-beta-glucanosyltransferase GAS3

1

0

High-throughput

0.480

High

1084874

YN11A
Transposon Ty1-NL1 Gag polyprotein

1

0

High-throughput

0.480

High

805584

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

8

Small-scale

0.479

High

916488

SUT1
Sterol uptake protein 1

1

2

Small-scale

0.479

High

815013

SLN1
Osmosensing histidine protein kinase SLN1

1

0

High-throughput

0.460

High

511878

RS24A
Small ribosomal subunit protein eS24A

1

1

High-throughput

0.457

High

600723

SEC2
Rab guanine nucleotide exchange factor SEC2

1

3

High-throughput

0.457

High

744722

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

2

High-throughput

0.457

High

747182

RT04
Small ribosomal subunit protein uS2m

1

1

High-throughput

0.457

High

797570

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

3

High-throughput

0.457

High

1039681

AAD16
Putative aryl-alcohol dehydrogenase AAD16

1

1

High-throughput

0.457

High

1043491

MGL2
Monoacylglycerol lipase

1

3

High-throughput

0.457

High

1043794

YMD7
Uncharacterized protein YML037C

1

1

High-throughput

0.457

High

1084973

AP2M
AP-2 complex subunit mu

1

2

High-throughput

0.457

High

796406

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

14

High-throughput

0.457

High

368779

PMG1
Phosphoglycerate mutase 1

1

3

High-throughput

0.457

High

525644

HSP71
Heat shock protein SSA1

1

19

High-throughput

0.445

High

528097

HSP72
Heat shock protein SSA2

1

19

High-throughput

0.445

High

546860

SSB1
Ribosome-associated molecular chaperone SSB1

1

19

High-throughput

0.445

High

742746

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

816487

HSP7E
Heat shock protein SSC3, mitochondrial

1

20

High-throughput

0.445

High

820201

SSB2
Ribosome-associated molecular chaperone SSB2

1

19

High-throughput

0.445

High

1056465

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

6

High-throughput

0.407

High

554456

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

0

High-throughput

0.279

Low

268906

MRP10
Small ribosomal subunit protein mS37

1

0

High-throughput

0.261

Low

585579

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

1084448

SSF2
Ribosome biogenesis protein SSF2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025