Protein: GCST
Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT) (Glycine decarboxylase complex subunit T)

Gene: GCST, GCV1
Organism: Saccharomyces cerevisiae S288C
Interactions: 19
UniProt ID: P48015

Gene Ontology (top 5):
GO:0004047 - aminomethyltransferase activity
GO:0005739 - mitochondrion
GO:0005960 - glycine cleavage complex
GO:0006544 - glycine metabolic process
GO:0006546 - glycine catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

813890

GCSH
Glycine cleavage system H protein, mitochondrial

1

0

High-throughput

0.586

High

594970

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

399855

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

456426

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.458

High

752472

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

869460

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

869461

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

869464

CSR1
Phosphatidylinositol transfer protein CSR1

1

0

High-throughput

0.458

High

527095

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

545463

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

747460

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.407

High

692397

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.261

Low

707560

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

709861

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

748460

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

812458

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

869459

NMA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

0

High-throughput

0.249

Low

869462

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.249

Low

869463

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025