Protein: EGFL7
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)

Gene: EGFL7
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q9UHF1

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001568 - blood vessel development
GO:0001570 - vasculogenesis
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005102 - signaling receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1408265

EGFL8
Epidermal growth factor-like protein 8

4

18

High-throughput

0.892

High

1010117

DLK1
Protein delta homolog 1

3

19

High-throughput

0.861

High

1047772

NOTC2
Neurogenic locus notch homolog protein 2

3

19

Small-scale

0.843

High

653743

PROZ
Vitamin K-dependent protein Z

2

19

High-throughput

0.811

High

1086457

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

18

High-throughput

0.811

High

1369247

NELL1
Protein kinase C-binding protein NELL1

2

19

High-throughput

0.811

High

1404106

NELL2
Protein kinase C-binding protein NELL2

2

18

High-throughput

0.811

High

437820

HEPS
Serine protease hepsin

2

13

High-throughput

0.776

High

1458870

FBLN5
Fibulin-5

2

20

High-throughput

0.776

High

1459916

NOTC3
Neurogenic locus notch homolog protein 3

2

20

Small-scale

0.744

High

1419457

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

12

High-throughput

0.726

High

1459914

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

2

12

High-throughput

0.726

High

1022496

IDD
Integral membrane protein DGCR2/IDD

1

16

High-throughput

0.691

High

857580

NOTC1
Neurogenic locus notch homolog protein 1

1

19

Small-scale

0.680

High

212500

SPIT2
Kunitz-type protease inhibitor 2

3

5

High-throughput

0.667

High

1387713

VWCE
von Willebrand factor C and EGF domain-containing protein

3

19

High-throughput

0.662

High

705596

GRN
Progranulin

3

0

High-throughput

0.638

High

350750

NOE2
Noelin-2

2

6

High-throughput

0.628

High

1404626

NOTC4
Neurogenic locus notch homolog protein 4

1

19

Small-scale

0.621

High

270182

LRP3
Low-density lipoprotein receptor-related protein 3

1

19

High-throughput

0.618

High

1213731

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

17

High-throughput

0.618

High

1459919

ST14
Suppressor of tumorigenicity 14 protein

1

14

High-throughput

0.618

High

189026

TMPS2
Transmembrane protease serine 2

1

13

High-throughput

0.618

High

627583

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

2

3

High-throughput

0.611

High

885443

HXA1
Homeobox protein Hox-A1

3

11

High-throughput

0.609

High

192138

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.602

High

1145713

RCN1
Reticulocalbin-1

2

1

High-throughput

0.601

High

376561

LDLR
Low-density lipoprotein receptor

1

13

High-throughput

0.575

High

654564

FBLN1
Fibulin-1

1

19

High-throughput

0.575

High

772346

FBN2
Fibrillin-2 [Cleaved into: Placensin]

1

19

High-throughput

0.575

High

1132148

LTBP2
Latent-transforming growth factor beta-binding protein 2

1

20

High-throughput

0.575

High

1249928

CCBE1
Collagen and calcium-binding EGF domain-containing protein 1

1

19

High-throughput

0.575

High

1324544

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

20

High-throughput

0.575

High

1366681

SORL
Sortilin-related receptor

1

12

High-throughput

0.575

High

62172

KLRG2
Killer cell lectin-like receptor subfamily G member 2

2

16

High-throughput

0.574

High

169786

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

5

High-throughput

0.553

High

1459912

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

11

High-throughput

0.553

High

1459918

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

2

2

High-throughput

0.553

High

1212874

UBR4
E3 ubiquitin-protein ligase UBR4

2

1

High-throughput

0.549

High

1254286

UBR3
E3 ubiquitin-protein ligase UBR3

2

1

High-throughput

0.549

High

282868

CRLF1
Cytokine receptor-like factor 1

1

8

High-throughput

0.536

High

342689

LY86
Lymphocyte antigen 86

1

5

High-throughput

0.536

High

369767

A2MG
Alpha-2-macroglobulin

1

3

High-throughput

0.536

High

389554

FINC
Fibronectin

1

9

High-throughput

0.536

High

518927

CCL3
C-C motif chemokine 3

1

15

High-throughput

0.536

High

535647

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.536

High

568006

PRG2
Bone marrow proteoglycan

1

12

High-throughput

0.536

High

933241

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

4

High-throughput

0.536

High

1396525

LCFC1
Sperm-egg fusion protein LLCFC1

1

6

High-throughput

0.536

High

1453779

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

3

High-throughput

0.536

High

608378

EGLN
Endoglin

1

0

High-throughput

0.513

High

1103113

MFAP5
Microfibrillar-associated protein 5

1

0

High-throughput

0.513

High

900210

FXR1
RNA-binding protein FXR1

1

2

High-throughput

0.494

High

900545

FXR2
RNA-binding protein FXR2

1

2

High-throughput

0.494

High

1277961

NUFP2
FMR1-interacting protein NUFIP2

1

4

High-throughput

0.494

High

270856

ROCK2
Rho-associated protein kinase 2

1

5

High-throughput

0.489

High

1448882

RAB6B
Ras-related protein Rab-6B

1

5

High-throughput

0.489

High

1459915

PNMA2
Paraneoplastic antigen Ma2

1

2

High-throughput

0.489

High

1392080

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

2

High-throughput

0.481

High

1217774

GFI1B
Zinc finger protein Gfi-1b

1

4

High-throughput

0.464

High

561157

GILT
Gamma-interferon-inducible lysosomal thiol reductase

1

0

High-throughput

0.458

High

1042670

UPAR
Urokinase plasminogen activator surface receptor

1

0

High-throughput

0.458

High

508788

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.457

High

465683

IGF1R
Insulin-like growth factor 1 receptor

1

7

High-throughput

0.457

High

167468

WNT9A
Protein Wnt-9a

1

10

High-throughput

0.445

High

183310

LAMA5
Laminin subunit alpha-5

1

20

High-throughput

0.445

High

535904

LAMC1
Laminin subunit gamma-1

1

20

High-throughput

0.445

High

673792

LAMA1
Laminin subunit alpha-1

1

20

High-throughput

0.445

High

709313

CCN2
CCN family member 2

1

5

High-throughput

0.445

High

937448

LAMB2
Laminin subunit beta-2

1

20

High-throughput

0.445

High

945918

INHBE
Inhibin beta E chain

1

5

High-throughput

0.445

High

1063894

LG3BP
Galectin-3-binding protein

1

9

High-throughput

0.445

High

1294393

FRAS1
Extracellular matrix organizing protein FRAS1

1

20

High-throughput

0.445

High

1360162

PATE1
Prostate and testis expressed protein 1

1

1

High-throughput

0.445

High

1382708

EMID1
EMI domain-containing protein 1

1

7

High-throughput

0.445

High

1453625

CRIM1
Cysteine-rich motor neuron 1 protein

1

19

High-throughput

0.445

High

1453628

SELN
Selenoprotein N

1

1

High-throughput

0.445

High

170408

AURKA
Aurora kinase A

1

4

High-throughput

0.437

High

331391

KI20A
Kinesin-like protein KIF20A

1

6

High-throughput

0.437

High

456027

ASGR2
Asialoglycoprotein receptor 2

1

12

High-throughput

0.437

High

787594

TNR3
Tumor necrosis factor receptor superfamily member 3

1

9

High-throughput

0.437

High

1114575

CUL3
Cullin-3

1

14

High-throughput

0.437

High

1140997

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.437

High

1249300

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1360015

LIPH
Lipase member H

1

2

High-throughput

0.437

High

1436819

WDR76
WD repeat-containing protein 76

1

9

High-throughput

0.437

High

1449985

T106B
Transmembrane protein 106B

1

5

High-throughput

0.437

High

230131

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

High-throughput

0.407

High

326081

UBR5
E3 ubiquitin-protein ligase UBR5

1

16

High-throughput

0.407

High

332255

UCP5
Brain mitochondrial carrier protein 1

1

2

High-throughput

0.407

High

1108260

SQSTM
Sequestosome-1

1

11

High-throughput

0.407

High

1121552

KEAP1
Kelch-like ECH-associated protein 1

1

3

High-throughput

0.407

High

1328690

KCD17
BTB/POZ domain-containing protein KCTD17

1

5

High-throughput

0.407

High

1338001

ZNT7
Zinc transporter 7

1

6

High-throughput

0.407

High

1346824

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

6

High-throughput

0.407

High

1393331

SAHH3
Adenosylhomocysteinase 3

1

1

High-throughput

0.407

High

1394172

AJUBA
LIM domain-containing protein ajuba

1

2

High-throughput

0.407

High

1447693

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

4

High-throughput

0.407

High

1451494

GID8
Glucose-induced degradation protein 8 homolog

1

2

High-throughput

0.407

High

1459917

CP131
Centrosomal protein of 131 kDa

1

5

High-throughput

0.407

High

1459920

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

6

High-throughput

0.407

High

1380555

PIGT
GPI-anchor transamidase component PIGT

2

0

High-throughput

0.328

High

66526

RASFA
Ras association domain-containing protein 10

2

0

High-throughput

0.316

High

1398180

HEXI2
Protein HEXIM2

2

0

High-throughput

0.316

High

1408121

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.316

High

1431784

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

0

High-throughput

0.316

High

822900

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.279

Low

1026268

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.279

Low

1316007

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

1308238

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.249

Low

343710

GGPPS
Geranylgeranyl pyrophosphate synthase

1

0

High-throughput

0.232

Low

960601

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.232

Low

1231202

TRI68
E3 ubiquitin-protein ligase TRIM68

1

0

High-throughput

0.232

Low

1359515

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.232

Low

1451599

TM160
Transmembrane protein 160

1

0

High-throughput

0.232

Low

1459913

FBX3
F-box only protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025