HitPredict

Interactor 1: PRGR (P06401)
Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3)
Gene: PGR

Interactor 2: PPP5 (P53041)
Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT)
Gene: PPP5C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20661446
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 933 Hs			1 499
+	Hs
		437629 MCR_HUMAN (12-933): 3.27e-105: 351: 29.16		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		377203 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		487258 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		858657 ESR2_HUMAN (453-926): 9.09e-93: 305: 22.80		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		369237 ESR1_HUMAN (398-917): 2.19e-90: 301: 20.82		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		487319 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		PP2AA_HUMAN (190-481): 5.28e-167: 475: 40.88
+	Hs
		437630 MCR_HUMAN (12-933): 3.27e-105: 351: 29.16		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79
+	Hs
		320201 ERR2_HUMAN (483-917): 5.66e-97: 313: 24.14		PP2AA_HUMAN (190-481): 5.28e-167: 475: 40.88
+	Hs
		320195 ERR2_HUMAN (483-917): 5.66e-97: 313: 24.14		PP2AB_HUMAN (182-485): 6.26e-163: 465: 38.69
+	Hs
		369364 ESR1_HUMAN (398-917): 2.19e-90: 301: 20.82		PP2AA_HUMAN (190-481): 5.28e-167: 475: 40.88
+	Hs
		487291 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		PP1B_HUMAN (203-490): 1.32e-154: 444: 36.09
+	Hs
		487290 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79
+	Hs
		915249 ESR2_HUMAN (453-926): 9.09e-93: 305: 22.80		PP2AB_HUMAN (182-485): 6.26e-163: 465: 38.69
+	Hs
		369332 ESR1_HUMAN (398-917): 2.19e-90: 301: 20.82		PP2AB_HUMAN (182-485): 6.26e-163: 465: 38.69
+	Hs
		737951 ESR2_HUMAN (453-926): 9.09e-93: 305: 22.80		PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88
+	Hs
		906550 ESR2_HUMAN (453-926): 9.09e-93: 305: 22.80		PP1B_HUMAN (203-490): 1.32e-154: 444: 36.09
+	Hs
		906054 ESR2_HUMAN (453-926): 9.09e-93: 305: 22.80		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79
+	Hs
		369103 ESR1_HUMAN (398-917): 2.19e-90: 301: 20.82		PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88
+	Hs
		369309 ESR1_HUMAN (398-917): 2.19e-90: 301: 20.82		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79
+	Mm
		587097 ESR1_MOUSE (418-917): 1.01e-88: 297: 21.62		PP1G_MOUSE (196-488): 1.32e-154: 444: 36.88