Protein: ELOC
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)

Gene: ELOC
Organism: Homo sapiens
Interactions: 233
UniProt ID: Q15369

Gene Ontology (top 5):
GO:0001222 - transcription corepressor binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0006367 - transcription initiation at RNA polymerase II promoter

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

822675

VHL
von Hippel-Lindau disease tumor suppressor

58

1

Small-scale

0.997

High

1147033

ELOB
Elongin-B

27

4

Small-scale

0.991

High

1147087

CUL5
Cullin-5

22

5

Small-scale

0.989

High

1112845

CUL2
Cullin-2

18

5

Small-scale

0.986

High

1147095

ASB9
Ankyrin repeat and SOCS box protein 9

11

8

Small-scale

0.974

High

193280

SOCS1
Suppressor of cytokine signaling 1

9

10

Small-scale

0.966

High

155113

SOCS2
Suppressor of cytokine signaling 2

7

10

Small-scale

0.960

High

1086737

RB40B
Ras-related protein Rab-40B

7

6

Small-scale

0.960

High

155947

SOCS3
Suppressor of cytokine signaling 3

6

10

Small-scale

0.950

High

1147089

SPSB4
SPRY domain-containing SOCS box protein 4

5

6

Small-scale

0.933

High

1147159

ASB3
Ankyrin repeat and SOCS box protein 3

5

4

Small-scale

0.925

High

156043

SOCS6
Suppressor of cytokine signaling 6

5

10

Small-scale

0.919

High

1147126

ASB8
Ankyrin repeat and SOCS box protein 8

5

6

Small-scale

0.919

High

1147110

SPSB2
SPRY domain-containing SOCS box protein 2

4

6

Small-scale

0.910

High

1147139

ASB6
Ankyrin repeat and SOCS box protein 6

4

3

Small-scale

0.894

High

1147106

ASB2
Ankyrin repeat and SOCS box protein 2

4

4

Small-scale

0.874

High

1147107

RB40C
Ras-related protein Rab-40C

3

6

Small-scale

0.873

High

1113167

CUL3
Cullin-3

3

6

High-throughput

0.864

High

1147076

RB40A
Ras-related protein Rab-40A

3

6

High-throughput

0.861

High

1147090

SPSB1
SPRY domain-containing SOCS box protein 1

3

6

Small-scale

0.849

High

1147160

ASB1
Ankyrin repeat and SOCS box protein 1

3

11

Small-scale

0.829

High

1147161

WSB1
WD repeat and SOCS box-containing protein 1

3

1

Small-scale

0.829

High

1147075

SOCS4
Suppressor of cytokine signaling 4

3

10

Small-scale

0.821

High

259988

BRD4
Bromodomain-containing protein 4

3

0

Small-scale

0.791

High

501774

RB40L
Ras-related protein Rab-40A-like

2

6

High-throughput

0.789

High

508013

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

2

Small-scale

0.768

High

241751

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.754

High

1147036

NEDD8
Ubiquitin-like protein NEDD8

2

0

Small-scale

0.748

High

1147039

HIF1A
Hypoxia-inducible factor 1-alpha

9

2

Small-scale

0.745

High

273311

SOCS5
Suppressor of cytokine signaling 5

2

10

Small-scale

0.743

High

1124334

ELOA1
Elongin-A

7

5

Small-scale

0.739

High

1147145

NRBP
Nuclear receptor-binding protein

5

2

Small-scale

0.716

High

983815

RBX1
E3 ubiquitin-protein ligase RBX1

4

2

Small-scale

0.689

High

1007562

PRAME
Melanoma antigen preferentially expressed in tumors

3

3

Small-scale

0.688

High

1147112

KLDC3
Kelch domain-containing protein 3

4

2

Small-scale

0.683

High

1147153

KLDC2
Kelch domain-containing protein 2

3

3

Small-scale

0.667

High

563802

CFTR
Cystic fibrosis transmembrane conductance regulator

4

0

High-throughput

0.658

High

1147146

FEM1B
Protein fem-1 homolog B

3

2

Small-scale

0.656

High

1147074

ASB11
Ankyrin repeat and SOCS box protein 11

1

5

Small-scale

0.647

High

1147061

CSN6
COP9 signalosome complex subunit 6

3

0

High-throughput

0.638

High

992765

RACK1
Small ribosomal subunit protein RACK1

3

0

Small-scale

0.636

High

66437

ASB14
Ankyrin repeat and SOCS box protein 14

1

4

High-throughput

0.618

High

1147057

ASB18
Ankyrin repeat and SOCS box protein 18

1

6

High-throughput

0.618

High

1147073

ASB5
Ankyrin repeat and SOCS box protein 5

1

9

High-throughput

0.618

High

1147077

ASB10
Ankyrin repeat and SOCS box protein 10

1

6

High-throughput

0.618

High

1147078

ASB15
Ankyrin repeat and SOCS box protein 15

1

4

High-throughput

0.618

High

1147079

ASB13
Ankyrin repeat and SOCS box protein 13

1

6

High-throughput

0.618

High

1147080

ASB12
Ankyrin repeat and SOCS box protein 12

1

7

High-throughput

0.618

High

1147105

ASB16
Ankyrin repeat and SOCS box protein 16

1

7

High-throughput

0.618

High

1147124

ASB7
Ankyrin repeat and SOCS box protein 7

1

5

High-throughput

0.618

High

1147133

CISH
Cytokine-inducible SH2-containing protein

1

10

Small-scale

0.618

High

1147114

NEUL2
Neuralized-like protein 2

1

0

Small-scale

0.614

High

1119504

PEBB
Core-binding factor subunit beta

3

0

Small-scale

0.613

High

320683

UBXN7
UBX domain-containing protein 7

2

1

Small-scale

0.611

High

335130

ARI2
E3 ubiquitin-protein ligase ARIH2

2

2

Small-scale

0.611

High

1147052

CTR9
RNA polymerase-associated protein CTR9 homolog

2

1

High-throughput

0.611

High

1147102

LLR1
Leucine-rich repeat protein 1

2

1

Small-scale

0.611

High

1147141

RBX2
RING-box protein 2

2

2

Small-scale

0.602

High

1147092

ANKR9
Ankyrin repeat domain-containing protein 9

2

0

Small-scale

0.602

High

1147062

ZER1
Protein zer-1 homolog

2

5

Small-scale

0.600

High

1147071

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

2

1

Small-scale

0.595

High

1136637

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.586

High

1147132

TULP4
Tubby-related protein 4

1

0

Small-scale

0.586

High

1147086

CSN5
COP9 signalosome complex subunit 5

2

0

High-throughput

0.585

High

1147100

DCNL1
DCN1-like protein 1

2

0

Small-scale

0.585

High

1147122

CHM4B
Charged multivesicular body protein 4b

2

1

High-throughput

0.584

High

1147066

COMD1
COMM domain-containing protein 1

2

0

Small-scale

0.577

High

1115202

CUL4B
Cullin-4B

1

5

High-throughput

0.575

High

396163

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

1139890

LRC14
Leucine-rich repeat-containing protein 14

2

3

High-throughput

0.571

High

1147099

MED8
Mediator of RNA polymerase II transcription subunit 8

1

1

Small-scale

0.562

High

1036518

ID2
DNA-binding protein inhibitor ID-2

1

2

Small-scale

0.561

High

1146368

LRC41
Leucine-rich repeat-containing protein 41

2

0

Small-scale

0.559

High

1147081

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

0

Small-scale

0.559

High

1147098

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

1147068

ARI1B
AT-rich interactive domain-containing protein 1B

1

0

Small-scale

0.537

High

1147041

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.536

High

1147063

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

1

High-throughput

0.536

High

1147094

FAF2
FAS-associated factor 2

1

1

High-throughput

0.536

High

1147111

EPAS1
Endothelial PAS domain-containing protein 1

1

2

High-throughput

0.536

High

1147115

FEM1A
Protein fem-1 homolog A

1

2

High-throughput

0.536

High

1147130

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

1

High-throughput

0.536

High

1147108

NOTC4
Neurogenic locus notch homolog protein 4

1

0

Small-scale

0.527

High

853269

CBX5
Chromobox protein homolog 5

1

0

High-throughput

0.518

High

1041824

CENPC
Centromere protein C

1

0

High-throughput

0.518

High

1147046

CPTP
Ceramide-1-phosphate transfer protein

1

0

High-throughput

0.518

High

1041532

KMT2A
Histone-lysine N-methyltransferase 2A

1

1

Small-scale

0.515

High

65631

EPOP
Elongin BC and Polycomb repressive complex 2-associated protein

1

0

High-throughput

0.513

High

867152

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

1143829

TCAL1
Transcription elongation factor A protein-like 1

1

0

High-throughput

0.513

High

1147038

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.513

High

1147085

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1147138

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

1147120

ZY11B
Protein zyg-11 homolog B

1

5

Small-scale

0.508

High

1147065

ELOA2
Elongin-A2

1

5

Small-scale

0.501

High

945144

CORO7
Coronin-7

1

0

Small-scale

0.493

High

65860

LR14B
Leucine-rich repeat-containing protein 14B

1

3

High-throughput

0.489

High

1147134

NRBP2
Nuclear receptor-binding protein 2

1

2

High-throughput

0.489

High

756211

MCM7
DNA replication licensing factor MCM7

1

0

Small-scale

0.480

High

67472

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

1

Small-scale

0.479

High

157411

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

256549

PRAM2
PRAME family member 2

1

3

Small-scale

0.479

High

298385

DNJC8
DnaJ homolog subfamily C member 8

1

1

High-throughput

0.479

High

400872

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

521356

ARAF
Serine/threonine-protein kinase A-Raf

1

1

High-throughput

0.479

High

563011

MYH6
Myosin-6

1

1

High-throughput

0.479

High

606800

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

693320

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

2

High-throughput

0.479

High

832311

ID1
DNA-binding protein inhibitor ID-1

1

2

Small-scale

0.479

High

1037100

ID3
DNA-binding protein inhibitor ID-3

1

2

Small-scale

0.479

High

1053367

CTSL2
CTD small phosphatase-like protein 2

1

1

High-throughput

0.479

High

1104407

ILK
Scaffold protein ILK

1

1

High-throughput

0.479

High

1139709

SETB1
Histone-lysine N-methyltransferase SETDB1

1

2

Small-scale

0.479

High

1147034

T22D1
TSC22 domain family protein 1

1

2

High-throughput

0.479

High

1147037

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1147044

SGO1
Shugoshin 1

1

1

High-throughput

0.479

High

1147049

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1147053

SPSB3
SPRY domain-containing SOCS box protein 3

1

6

Small-scale

0.479

High

1147054

BCOR
BCL-6 corepressor

1

2

High-throughput

0.479

High

1147082

APBP2
Amyloid protein-binding protein 2

1

1

Small-scale

0.479

High

1147083

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1147097

DYL2
Dynein light chain 2, cytoplasmic

1

1

High-throughput

0.479

High

1147118

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

1

High-throughput

0.479

High

1147136

DJC11
DnaJ homolog subfamily C member 11

1

1

High-throughput

0.479

High

1147148

CSN3
COP9 signalosome complex subunit 3

1

1

High-throughput

0.479

High

1147155

FBX7
F-box only protein 7

1

1

High-throughput

0.479

High

1147157

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

1147158

ARI1
E3 ubiquitin-protein ligase ARIH1

1

2

High-throughput

0.479

High

1147127

ECT2
Protein ECT2

1

0

High-throughput

0.460

High

132055

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

194205

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

315614

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

324886

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

370303

CYTA
Cystatin-A

1

0

High-throughput

0.458

High

424199

S10A8
Protein S100-A8

1

0

High-throughput

0.458

High

538964

EPB41
Protein 4.1

1

0

High-throughput

0.458

High

542528

TOP2A
DNA topoisomerase 2-alpha

1

0

Small-scale

0.458

High

695527

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

766203

NOS2
Nitric oxide synthase, inducible

1

0

Small-scale

0.458

High

768257

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

772389

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

Small-scale

0.458

High

775103

FUS
RNA-binding protein FUS

1

0

High-throughput

0.458

High

830785

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

851567

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

861174

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

904748

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

933645

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

Small-scale

0.458

High

940972

HDAC4
Histone deacetylase 4

1

0

High-throughput

0.458

High

947196

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

957394

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

959167

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

970546

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

979699

H4
Histone H4

1

0

High-throughput

0.458

High

991181

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

0

High-throughput

0.458

High

993581

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.458

High

1023237

RBM3
RNA-binding protein 3

1

0

Small-scale

0.458

High

1033685

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1101817

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.458

High

1107738

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

1129228

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

Small-scale

0.458

High

1138231

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1140310

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1146671

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.458

High

1147040

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1147043

CENPW
Centromere protein W

1

0

Small-scale

0.458

High

1147047

PPRC1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

1

0

High-throughput

0.458

High

1147050

TET2
Methylcytosine dioxygenase TET2

1

0

Small-scale

0.458

High

1147051

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1147055

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

1147060

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.458

High

1147064

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1147067

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1147070

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.458

High

1147072

DNJA4
DnaJ homolog subfamily A member 4

1

0

High-throughput

0.458

High

1147091

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.458

High

1147093

SGK3
Serine/threonine-protein kinase Sgk3

1

0

High-throughput

0.458

High

1147104

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1147109

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1147113

MBB1A
Myb-binding protein 1A

1

0

Small-scale

0.458

High

1147116

PCGF1
Polycomb group RING finger protein 1

1

0

High-throughput

0.458

High

1147117

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.458

High

1147119

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1147125

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1147128

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1147129

MOV10
Helicase MOV-10

1

0

Small-scale

0.458

High

1147131

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

Small-scale

0.458

High

1147142

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

0

Small-scale

0.458

High

1147143

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1147147

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

1147150

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.458

High

1147151

FBW1A
F-box/WD repeat-containing protein 1A

1

0

Small-scale

0.458

High

619222

EPOR
Erythropoietin receptor

1

1

Small-scale

0.457

High

1147140

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1147156

T22D4
TSC22 domain family protein 4

1

1

High-throughput

0.437

High

244974

KATIP
Katanin-interacting protein

1

0

High-throughput

0.426

High

404797

PRIO
Major prion protein

1

0

High-throughput

0.426

High

529845

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

942628

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

1031790

LAT1
Large neutral amino acids transporter small subunit 1

1

0

High-throughput

0.426

High

1147045

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

533851

GHR
Growth hormone receptor

1

1

Small-scale

0.408

High

886879

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

1147048

MT21C
Protein-lysine methyltransferase METTL21C

4

0

High-throughput

0.364

High

1147058

UBP51
Ubiquitin carboxyl-terminal hydrolase 51

1

0

Small-scale

0.292

High

165125

RASM
Ras-related protein M-Ras

1

0

High-throughput

0.282

High

303680

JTB
Protein JTB

1

0

High-throughput

0.282

High

904429

CP2J2
Cytochrome P450 2J2

1

0

High-throughput

0.282

High

942201

WNT7B
Protein Wnt-7b

1

0

High-throughput

0.282

High

1124105

RCAN2
Calcipressin-2

1

0

High-throughput

0.282

High

1147035

EFNB3
Ephrin-B3

1

0

High-throughput

0.282

High

1147144

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.282

High

1147042

SETMR
Histone-lysine N-methyltransferase SETMAR

1

0

High-throughput

0.279

Low

1147152

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

254612

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.269

Low

1147088

EXT2
Exostosin-2

1

0

High-throughput

0.269

Low

1147096

SAT2
Thialysine N-epsilon-acetyltransferase

1

0

Small-scale

0.261

Low

105976

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

293725

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

458408

ADRB2
Beta-2 adrenergic receptor

1

0

Small-scale

0.249

Low

1116204

PTC1
Protein patched homolog 1

1

0

Small-scale

0.249

Low

1147056

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1147059

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

1147069

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1147084

IOD2
Type II iodothyronine deiodinase

1

0

Small-scale

0.249

Low

1147101

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1147103

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

0

High-throughput

0.249

Low

1147121

DJC25
DnaJ homolog subfamily C member 25

1

0

High-throughput

0.249

Low

1147123

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1147135

PCMD2
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2

1

0

Small-scale

0.249

Low

1147137

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1147154

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

255034

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

1147149

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025