Protein: SYL
Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)

Gene: SYL, leuS
Organism: Escherichia coli K-12
Interactions: 26
UniProt ID: P07813

Gene Ontology (top 5):
GO:0002161 - aminoacyl-tRNA deacylase activity
GO:0004823 - leucine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006429 - leucyl-tRNA aminoacylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

460399

DNLJ
DNA ligase

3

1

High-throughput

0.669

High

444267

TOP1
DNA topoisomerase 1

2

2

High-throughput

0.608

High

460398

MAP1
Methionine aminopeptidase

2

1

High-throughput

0.588

High

450086

RF2
Peptide chain release factor RF2

2

9

High-throughput

0.584

High

460406

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.563

High

460386

CH60
Chaperonin GroEL

1

4

High-throughput

0.536

High

460404

MTOX
N-methyl-L-tryptophan oxidase

1

1

High-throughput

0.536

High

460405

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

393940

RBSB
Ribose import binding protein RbsB

1

3

High-throughput

0.494

High

460401

HYAD
Hydrogenase 1 maturation protease

1

1

High-throughput

0.494

High

460407

GNGF
Putative gluconeogenesis factor

1

2

High-throughput

0.494

High

460396

RS2
Small ribosomal subunit protein uS2

1

4

High-throughput

0.489

High

460392

RL11
Large ribosomal subunit protein uL11

1

3

High-throughput

0.484

High

460394

RS10
Small ribosomal subunit protein uS10

1

3

High-throughput

0.484

High

460391

RF1
Peptide chain release factor RF1

1

9

High-throughput

0.479

High

460393

RL7
Large ribosomal subunit protein bL12

1

0

High-throughput

0.464

High

460387

CH10
Co-chaperonin GroES

1

0

High-throughput

0.458

High

460388

COAD
Phosphopantetheine adenylyltransferase

1

0

High-throughput

0.458

High

460389

KPRS
Ribose-phosphate pyrophosphokinase

1

0

High-throughput

0.458

High

460390

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.458

High

460403

HTRE
Outer membrane usher protein HtrE

3

0

High-throughput

0.349

High

460408

DGCP
Diguanylate cyclase DgcP

2

0

High-throughput

0.318

High

460400

HYCE
Formate hydrogenlyase subunit 5

1

0

High-throughput

0.279

Low

460402

YJBH
Uncharacterized lipoprotein YjbH

1

0

High-throughput

0.279

Low

460395

RS16
Small ribosomal subunit protein bS16

1

0

High-throughput

0.253

Low

460397

RL23
Large ribosomal subunit protein uL23

1

0

High-throughput

0.253

Low


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Last updated: 11Aug2025