HitPredict - High confidence protein-protein interactions

Protein: HMAL2
Silenced mating-type protein ALPHA2 (MATalpha2 protein) (Alpha-2 repressor)

Gene: HMAL2, HMLALPHA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 9
UniProt ID: P0CY09

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0007531 - mating type determination
GO:0008301 - DNA binding, bending

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
515404	HMRA1 Silenced mating-type protein A1	11	0	Small-scale	0.923	High
515405	MCM1 Pheromone receptor transcription factor	3	1	Small-scale	0.834	High
515403	HMAL2 Silenced mating-type protein ALPHA2	1	0	Small-scale	0.614	High
515408	SLX5 E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5	2	0	Small-scale	0.603	High
515409	SLX8 E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8	2	0	Small-scale	0.577	High
515407	TUP1 General transcriptional corepressor TUP1	1	0	Small-scale	0.504	High
515406	CYC8 General transcriptional corepressor CYC8	1	0	Small-scale	0.480	High
515391	MTAL1 Mating-type protein ALPHA1	1	0	Small-scale	0.426	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025