Interactor 1: EZH1 (P70351)
Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.356) (ENX-2) (Enhancer of zeste homolog 1)
Gene: EZH1
Interactor 2: EHMT2 (Q9Z148)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Protein G9a)
Gene: EHMT2
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25680957 |
| Identification Methods | proximity labelling technology, affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ezh2_MCSS~SET, SET~preSET_CXC, Ank~SET, Pre-SET~SET |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0046976 - histone H3K27 methyltransferase activity |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
